The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.
The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.
Submissions from 2010
Open Repair and Endovascular Covered Stent Placement in the Management of Bilateral Axillary Artery Aneurysms, Douglas A. Troutman, Chittur R. Mohan, Farouq A. Samhouri, and Richard L. Sohn
Unique precursors for the mesenchymal cells involved in injury response and fibrosis, J. L. Walker, N. Zhai, L. Zhang, B. Bleaken, I. Wolff, Jacquelyn Gerhart, Mindy George-Weinstein, and A. S. Menko
Cardiovascular Agents, Ted Walton and Rebekah Thomas
Structure-activity relationships in the cytoprotective effect of caffeic acid phenethyl ester (CAPE) and fluorinated derivatives: effects on heme oxygenase-1 induction and antioxidant activities, Xinyu Wang, Salomon Stavchansky, Sean M. Kerwin, and Phillip D. Bowman
The Functions of ISG15 Ubiquitin-like Modifier and its Modifier Enzymes, Xinxing Wan, Dianzheng Zhang, and Hanchun Chen
Brain MRI image segmentation using fuzzy C-means clustering, Y. Wei, H. Keith Brown, X. Tao, and S. Moore
Estrogen and oxidative stress: A novel mechanism that may increase the risk for cardiovascular disease in women, Richard E. White, Ross Gerrity, Scott A. Barman, and Guichun Han
Development of acetaminophen proline prodrug, Zhiqian Wu, Ashish Patel, Rutesh Dave, and Xudong Yuan
Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cells, Zhiqian Wu, Anandkumar Shah, Namrata Patel, and Xudong Yuan
The dual role of TNF in pulmonary edema, Guang Yang, Boris Gorshkov, Supriya Sridhar, Alexander Verin, Rudolf Lucas, Jurg Hamacher, Richard E. White, and Trinad Chakraborty
The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery, Xudong Yuan, Bruhal Shah, Naimish K. Kotadia, Jian Li, Hua Gu, and Zhiqian Wu
Numerical Modeling of Oxygen Distributions in Cortical and Cancellous Bone: Oxygen Availability Governs Osteonal and Trabecular Dimensions, Adam M. Zahm, Michael A. Bucaro, Portonovo S. Ayyaswamy, Vickram Srinivas, Irving M. Shapiro, Christopher S. Adams, and Karthik Mukundakrishnan
Submissions from 2009
Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis, Christopher S. Adams, V. Antoci Jr., G. Harrison, P. Patal, T. A. Freeman, I. M. Shapiro, J. Parvizi, N. J. Hickok, S. Radin, and P. Ducheyne
Ajoene exerts potent effects in 3t3-l1 adipocytes by inhibiting adipogenesis and inducing apoptosis i, Suresh Ambati, Jeongyeh Yang, Srujana Rayalam, Hea Jin Park, Mary Anne Della-Fera, and Clifton A. Baile
Factors That Influence Physicians to Practice in Rural Locations: A Review and Commentary, Darra Ballance, Denise Kornegay, and Paul Evans
Sickle cell disease, Lamia P. Barakat, D Collette Nicolaou, Emily A. O'Hara, and Sarah Levin Allen
Complementary and Alternative Medicines for the Treatment of Diabetes, Kimberly L. Barefield and Melissa C. Jones
Diabetes-Related Medication-Induced Hypoglycemia, Kimberly L. Barefield and Scott Lancaster
RhoA/Rho-kinase signaling: A therapeutic target in pulmonary hypertension, Scott A. Barman, Shu Zhu, and Richard E. White
Application of osteopathy in the cranial field to successfully treat vertigo:A case series, Murray R. Berkowitz
Editorial, Murray R. Berkowitz
Osteopathic education and training-Advocating the adoption of an external paradigm for residency training in NMM/OMM, Murray R. Berkowitz
Hip Fractures in Children, Matthew J. Boardman, Martin J. Herman, Brian Buck, and Peter D. Pizzutillo
Regulation of autophagy in human and murine cartilage: Hypoxia-inducible factor 2 suppresses chondrocyte autophagy, J. Bohensky, S. P. Terkhorn, T. A. Freeman, Christopher S. Adams, J. A. Garcia, I. M. Shapiro, and V. Srinivas
Expression of transcription factor zinc-binding protein-89 (ZBP-89) is inhibited by inflammatory cytokines., Ruth C. Borghaei and Mariah Chambers
NF-kB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter, Ruth C. Borghaei, G. Gorski, and Masoud Javadi
Research Highlights, Erica N. Bozeman, Jennifer D. Hood, Rangaiah Shashidharamurthy, and Periasamy Selvaraj
Surface engineering of microparticles by novel protein transfer for targeted antigen/drug delivery, Gary W. Bumgarner, Rangaiah Shashidharamurthy, Shanmugam Nagarajan, Martin J. D'Souza, and Periasamy Selvaraj
To the point: reviews in medical education-the Objective Structured Clinical Examination, P. M. Casey, A. R. Goepfert, E. L. Aspey, M. M. Hammond, Joseph M. Kaczmarczyk, N. T. Katz, J. J. Neutens, F. S. Nuthalapaty, and E. Peskin
Acute lung injury: Apoptosis and signaling mechanisms, M. Chopra, J. S. Reuben, and Avadhesh C. Sharma
Contractile response of norepinephrine is modulated by caspase-3 in adult rat ventricular myocytes isolated from septic rat heart, M. Chopra and Avadhesh C. Sharma
A Novel Approach to the Dissection of the Human Knee, F Richard Clemente, Philip A. Fabrizio, and Michael Shumaker
Upregulation of myocardial syntaxin1A is associated with an early stage of polymicrobial sepsis, P. Das, M. Chopra, and Avadhesh C. Sharma
Age-dependent differential expression of apoptosis markers in the gingival tissue, P. Das, M. Chopra, Y. Sun, D. G. Kerns, S. Vastardis, and Avadhesh C. Sharma
Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis, Jayasri Das Sarma, Lawrence C. Kenyon, Susan T. Hingley, and Kenneth S. Shindler
Outcome trajectories in drug court: Do all participants have serious drug problems?, D. DeMatteo, D. Marlowe, David Festinger, and P. Arabia
Clinical Competencies and the Basic Sciences: An Online Case Tutorial Paradigm for Delivery of Integrated Clinical and Basic Science Content, Camille DiLullo, Harry J. Morris, and Richard M. Kriebel
The other diversity: The cost of being GLBT in America's health care, Terri A. Erbacher, Yuma Tomes, Tania Wismar, Caitlin Gilmartin, Deanna Ryder, Narrimone Thammavongsa, Eric Watson, and Lauren Webb
Special topic: Research brief, W. P. Erchul, George J. DuPaul, M. S. Bennett, P. F. Grissom, A. K. Jitendra, Katy E. Tresco, R. J. Volpe, R. E. Vile Junod, L. M. Flammer-Rivera, and M. C. Mannella
Ergonomic Intervention in the Treatment of a Patient with Upper Extremity and Neck Pain, Philip A. Fabrizio
The SEIQoL-DW for Assessing Quality of Life in ALS: Strengths and Limitations, Stephanie H. Felgoise, Jessica L. Stewart, Barbara A. Bremer, Susan M. Walsh, Mark B. Bromberg, and Zachary Simmons
Monetary Incentives Improve Recall of Research Consent Information: It Pays to Remember, David Festinger, D. Marlowe, J. Croft, K. Dugosh, P. Arabia, and K. Benasutti
Loneliness as a Partial Mediator of the Relation Between Low Social Preference in Childhood and Anxious/Depressed Symptoms in Adolescence, Reid Griffith Fontaine, Chongming Yang, Virginia Salzer Burks, Kenneth A. Dodge, Joseph M. Price, Gregory S. Pettit, and John E. Bates
Insulin Analog Therapy: Improving the Match with Physiologic Insulin Secretion, Jeffrey S. Freeman
Role of the Incretin Pathway in the Pathogenesis of Type 2 Diabetes Mellitus, Jeffrey S. Freeman
Case Report: Tackling Challenges of Postherpetic Neuralgia, Katherine E. Galluzzi
Managing Herpes Zoster and Postherpetic Neuralgia, Katherine E. Galluzzi
Noggin producing, MyoD-positive cells are crucial for eye development, Jacquelyn Gerhart, J. Pfautz, C. Neely, J. Elder, K. DuPrey, A. Menko, K. Knudsen, and Mindy George-Weinstein
South Asian subcontinent not represented in international pharmacy education supplement, Naushad Ghilzai
A novel short hairpin RNA (shRNA) expression system promotes Sox9-dependent gene silencing, J. R. Gilbert, Christopher S. Adams, I. M. Shapiro, and N. J. Hickok
Anthrax toxin: Pathologic effects on the cardiovascular system, H. B. Golden, L. E. Watson, H. Lal, S. K. Verma, D. M. Foster, S. R. Kuo, Avadhesh C. Sharma, A. Frankel, and D. E. Dostal
Bilateral Occult Mucosal Bridges of the True Vocal Folds, John Gull, Venu Divi, Mahmoud Ghaderi, and Robert T. Sataloff
The Comorbidity of Psychopathology in Cognitive and Academic SLD Subtypes, Lisa A. Hain, James B. Hale, and Jessica Glass Kendorksi
Development and Validation of an Attention-Deficit/Hyperactivity Disorder (ADHD) Executive Function and Behavior Rating Screening Battery, James B. Hale, Linda A. Reddy, Scott L. Decker, Rebecca Thompson, Julie N. Henzel, Annemarie Teodori, Elizabeth Forrest, Eleazar Eusebio, and Martha Bridge Denckla
Essential role of the 90-kilodalton heat shock protein in mediating nongenomic estrogen signaling in coronary artery smooth muscle, Guichun Han, Handong Ma, Rajesh Chintala, David J. R. Fulton, Scott A. Barman, and Richard E. White
Specification of the cardiac conduction system by transcription factors, Cathy J. Hatcher and Craig T. Basson
Successful outcome after early combined liver and en bloc-kidney transplant in an infant with primary hyperoxaluria type 1: A case report, Thomas Heffron, John Rodriguez, Carlos G. Fasola, Katherine Casper, Todd Pillen, Gregory Smallwood, Barry Warshaw, and Rene Romero
Delayed Salicylate Toxicity with Undetectable Initial Levels after Large-Dose Aspirin Ingestion, Joseph Herres, Danielle Ryan, and Matthew Salzman
Robust, High-Throughput Solution Structural Analyses by Small Angle X-Ray Scattering (SAXS), Greg L. Hura, Angeli L. Menon, Michal Hammel, Robert P. Rambo, Farris L. Poole, Susan E. Tsutakawa, Francis E. Jenney, Scott Classen, Kenneth A. Frankel, Robert C. Hopkins, Sung-Jae Yang, Joseph W. Scott, Bret D. Dillard, Michael W. W. Adams, and John A. Tainer
Adoption and Safe Families Act State Statutes Regarding Parents with Mental Illnesses: A Review and Targeted Intervention, Katy Kaplan, Petra Kottsieper, Jeniece Scott, Mark S. Salzer, and Phyllis Solomon
TGF-β upregulation drives tertiary lymphoid organ formation and kidney dysfunction in calcineurin A-α heterozygous mice, F. M. Kelly, R. N. Reddy, B. R. Roberts, S. Gangappa, I. R. Williams, and Jennifer L. Gooch
Topographic features retained after antibiotic modification of Ti alloy surfaces: Retention of topography with attachment of antibiotics, C. Ketonis, J. Parvizi, Christopher S. Adams, I. M. Shapiro, and N. J. Hickok
Clinical Performance of the TRUE2go Blood Glucose System-A Novel Integrated System for Meter and Strips, Mark S. Kipnes, Hal Joseph, Harry J. Morris, Jason Manko, and Douglas E. Bell
Myosin-II Negatively Regulates minor process extension and the temporal development of neuronal polarity, K. M. Kollins, J. Hu, Yueqiao Huang, and G. Gallo
Experiential knowledge of serious mental health problems: One clinician and academic's perspective, Petra Kottsieper
Correlation between an email based board review program and American Board of Pediatrics General Pediatrics Certifying Examination scores., E. E. Langenau, J. Fogel, H. A. Schaeffer, and Wilson
Ready, Willing, and Able to Provide MTM Services? A Survey of Community Pharmacists in the USA, Anandi V. Law, Mark P. Okamoto, and Kelly Brock
Overexpression of truncated ERG from TMPRSS2-ERG fusion and prostate cancer development , Melanie Leong, Wenfeng Shi, Jun Tian, Ellen Cho, Abbas Raza, Saquib A. Siddiqi, Abdulhafez Selim, Hanchun Chen, and Dianzheng Zhang
Neuronal CaMKII acts as a structural kinase, Yuchih Lin and Lori Redmond Hardy
Effects of MS23 on KCl-, a-adrenoceptor agonists- and U46619-induced contractions of arteries isolated from rat different organs, Y. Liu, Ming-sheng Zhang, Desuo Wang, D. B. Liu, W. X. Xue, L. G. Niu, and Y. Q. Liang
Activation of glycogen synthase kinase-3ß is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex, Yan-Chun Li, Dong Xi, Joy Roman, Yueqiao Huang, and Wen-Jun Gao
3D electron microscopic reconstruction of segments of rat cerebellar Purkinje cell dendrites receiving ascending and parallel fiber granule cell synaptic inputs, Huo Lu, Angelica V. Esquivel, and James M. Bower
Physiologically evoked neuronal current MRI in a bloodless turtle brain: Detectable or not?, Qingfei Luo, Huo Lu, Hanbing Lu, David Senseman, Keith Worsley, Yihong Yang, and Jia-Hong Gao
Middle Adulthood and Aging, Burton Mach and D. Baron
Adaptive interventions may optimize outcomes in drug courts: A pilot study, D. Marlowe, David Festinger, P. Arabia, K. Dugosh, and K. Benasutti
Reassessment of the Cranial Characters of Glossotherium and Paramylodon (Mammalia: Xenarthra: Mylodontidae), Robert McAfee
Applying an Executive Function Framework in Educational Therapy, George McCloskey
Clinical applications I: A neuropsychological approach to interpretation of the WAIS-IV and the use of the WAIS-IV in learning disability assessments, George McCloskey
The WISC-IV Integrated, George McCloskey
Executive functions and emotional disturbance, George McCloskey, Joseph Hewitt, Julie N. Henzel, and Eleazar Eusebio
Assessment and intervention for executive function difficulties, George McCloskey, Lisa A. Perkins, and Bob Van Divner
Reducing Disruptive Behavior in an Urban School Cafeteria: An Extension of the Good Behavior Game, Barry L. McCurdy, Amanda L. Lannie, and Ernesto Barnabas
Novel multiprotein complexes identified in the hyperthermophilic archaeon pyrococcus furiosus by non-denaturing fractionation of the native proteome, A. L. Menon, F. L. Poole II, A. Cvetkovic, S. A. Trauger, E. Kalisiak, J. W. Scott, S. Shanmukh, J. Praissman, Francis E. Jenney Jr., and et al.
Current Diagnosis and Treatment [Media Review], Bohdan Minczak
The underrecognized epilepsy spectrum: The effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production, Mark Mintz, Daniel Legoff, Jean Scornaienchi, Micah Brown, Sarah Levin Allen, Pnina Mintz, and Cathy Smith
Risk-Assessment Tools for Detecting Undiagnosed Diabetes., Eugene Mochan and Mark H. Ebell
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy, Heather L. Montie, Maria Cho, Latia Holder, Yuhong Liu, Andrey S. Tsvetkov, Steven Finkbeiner, and Diane E. Merry
Autophagy and access: Understanding the role of androgen receptor subcellular localization in SBMA, Heather L. Montie and Diane E. Merry
Problem Solving Skills Predict Quality of Llife and Psychological Morbidity in ALS Caregivers, Virginia Murphy, Stephanie H. Felgoise, Susan M. Walsh, and Zachary Simmons
An 11-Year-Old Boy with a Patella Fracture, Jason A. Nydick, Martin J. Herman, and Jean-Pierre de Chadarévian
Regression Analysis for Prediction: Understanding the Process, Phillip B. Palmer and Dennis G O'Connell
Genistein inhibits differentiation of primary human adipocytes, Heajin Park, Mary Anne Della-Fera, Dorothy B. Hausman, Srujana Rayalam, Suresh Ambati, and Clifton A. Baile
Thiazolidinediones and Congestive Heart Failure: A Judicious Balance of Risks and Benefits, Rujul R. Patel
Functional interactions between distinct sodium channel cytoplasmic domains through the action of calmodulin, F. Potet, B. Chagot, Mircea Anghelescu, P. Viswanathan, S. J. Stepanovic, S. Kuperschmidt, W. J. Chazin, and J. R. Balser
School-based interventions for students with attention-deficit/ hyperactivity disorder, T. J. Power, Katy E. Tresco, and M. C. Cassano
Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes, Srujana Rayalam, Jeongyeh Yang, Mary Anne Della-Fera, Heajin Park, Suresh Ambati, and Clifton A. Baile
Patient note fabrication and consequences of unprofessional behavior in a high-stakes clinical skills licensing examination, J. M. Sandella, W. L. Roberts, L. A. Gallagher, J. R. Gimpel, E. E. Langenau, and J. R. Boulet
Soy phytoestrogens are neuroprotective against stroke-like injury in vitro, D. A, Schreifhofer and Lori Redmond Hardy
Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fcγ receptor CD32A, Rangaiah Shashidharamurthy, Fang Zhang, Aaron Amano, Aparna Kamat, Ravichandran Panchanathan, Daniel Ezekwudo, Cheng Zhu, and Periasamy Selvaraj