The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.
The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.
Submissions from 2009
An 11-Year-Old Boy with a Patella Fracture, Jason A. Nydick, Martin J. Herman, and Jean-Pierre de Chadarévian
Regression Analysis for Prediction: Understanding the Process, Phillip B. Palmer and Dennis G O'Connell
Genistein inhibits differentiation of primary human adipocytes, Heajin Park, Mary Anne Della-Fera, Dorothy B. Hausman, Srujana Rayalam, Suresh Ambati, and Clifton A. Baile
Thiazolidinediones and Congestive Heart Failure: A Judicious Balance of Risks and Benefits, Rujul R. Patel
Functional interactions between distinct sodium channel cytoplasmic domains through the action of calmodulin, F. Potet, B. Chagot, Mircea Anghelescu, P. Viswanathan, S. J. Stepanovic, S. Kuperschmidt, W. J. Chazin, and J. R. Balser
School-based interventions for students with attention-deficit/ hyperactivity disorder, T. J. Power, Katy E. Tresco, and M. C. Cassano
Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes, Srujana Rayalam, Jeongyeh Yang, Mary Anne Della-Fera, Heajin Park, Suresh Ambati, and Clifton A. Baile
Patient note fabrication and consequences of unprofessional behavior in a high-stakes clinical skills licensing examination, J. M. Sandella, W. L. Roberts, L. A. Gallagher, J. R. Gimpel, E. E. Langenau, and J. R. Boulet
Soy phytoestrogens are neuroprotective against stroke-like injury in vitro, D. A, Schreifhofer and Lori Redmond Hardy
Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fcγ receptor CD32A, Rangaiah Shashidharamurthy, Fang Zhang, Aaron Amano, Aparna Kamat, Ravichandran Panchanathan, Daniel Ezekwudo, Cheng Zhu, and Periasamy Selvaraj
Repressive effects of resveratrol on androgen receptor transcriptional activity, Wenfeng Shi, Melanie Leong, Ellen Cho, Joseph Farrell, Hanchun Chen, Jun Tian, and Dianzheng Zhang
A 2-base pair deletion polymorphism in the partial duplication of the a7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia, Melissa L. Sinkus, Michael Lee, Judith Gault, Judith Logel, Margaret Short, Robert Freedman, Susan L. Christian, Jennifer Lyon, and Sherry Leonard
Cognitive-Behavioral Therapy for Anxiety-Disordered Youth: Secondary Outcomes from a Randomized Clinical Trial Evaluating Child and Family Modalities, Cynthia Suveg, Jennifer L. Hudson, Gene Brewer, Ellen C. Flannery-Schroeder, Elizabeth A. Gosch, and Philip C. Kendall
HLA Class I (ABC) Upregulation on Peripheral Blood CD3+/CD8+ T Lymphocyte Surface is a Potential Predictor of Acute Rejection in Renal Transplantation, Jun Tian, Wen-Feng Shi, Lu-Wei Zhang, Nan Lu, Xian-Quan Cui, Wan-Hua Xian, Huai-Bin Sun, En-Gang Li, Li-Na Geng, Dianzheng Zhang, and Xiong Zou
Effect of functional end groups of silane self-assembled monolayer surfaces on apatite formation, fibronectin adsorption and osteoblast cell function, G. K. Toworfe, S. Battacharyya, R. J. Composto, Christopher S. Adams, I. M. Shapiro, and P. Ducheyne
Osteopathic Medical Graduates in ACGME Residencies: A Threat to the Core Philosophy and Distinctiveness of Osteopathic Medicine, Kenneth J. Veit
TJ-41 Induces apoptosis and potentiates the apoptotic effects of 5-FU in breast cancer cell lines, Suresh Volate, Robert Hudson, Desuo Wang, Stephanie Muga, and Michael Wargovich
Special topic, research brief, R. J. Volpe, George J. DuPaul, A. K. Jitendra, and Katy E. Tresco
Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats, Xinyu Wang, Jihai Pang, Jacqueline A. Maffucci, Devandra S. Patel, Robert A. Newman, Sean M. Kerwin, Phillip D. Bowman, and Salomon Stavchansky
A Community Health Center's Diabetes Project: A Strategy to Reduce Health Disparities, Shoshana Wernick, Rhonda Lewis-Moss, Mary Williams, and Beverly White
HPLC/MS/MS analysis of 3-carbamyl-4-methylpyrrole analog MNP001, a highly potent antihypertensive agent, in rat plasma, Binfeng Xia, Ting Wang, Laura M. Fox, and Desuo Wang
Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail, Jeongyeh Yang, Mary Anne Della-Fera, Srujana Rayalam, Heajin Park, Suresh Ambati, Dorothy B. Hausman, Diane L. Hartzell, and Clifton A. Baile
Octanoate and decanoate induce apoptosis in 3T3-L1 adipocytes, Jeongyeh Yang, Srujana Rayalam, Mary Anne Della-Fera, Suresh Ambati, and Clifton A. Baile
Pathogenesis and therapy of autoimmunity-induced dilated cardiomyopathy, P. Zhao, Avadhesh C. Sharma, and J. Ren
Mutation of protein kinase C phosphorylation site S1076 on α-subunits affects BKCa channel activity in HEK-293 cells, Shu Zhu, Darren D. Browning, Richard E. White, David Fulton, and Scott A. Barman
Submissions from 2008
The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection, V. Antoci Jr., Christopher S. Adams, J. Parvizi, H. M. Davidson, R. J. Composto, T. A. Freeman, E. Wickstrom, P. Ducheyne, D. Jungkind, and I. M. Shapiro
Maze Suite 1.0: A complete set of tools to prepare, present, and analyze navigational and spatial cognitive neuroscience experiments, Hasan Ayaz and Sarah Levin Allen
Chlamydophila pneumoniae and the Etiology of Late-Onset Alzheimer's Disease, Brian J. Balin, Christopher Scott Little, Christine J. Hammond, Denah M. Appelt, Judith A. Whittum-Hudson, Hervé C. Gérard, and Alan P. Hudson
Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury, Vishakha Bhave, Shashikiran Donthamsetty, John R. Latendresse, and Harihara M. Mehendal
Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2, Vishakha Bhave, Shashikiran Donthamsetty, John R. Latendresse, Levan Muskhelishvili, and Harihara M. Mehendale
Hydrogenesis in hyperthermophilic microorganisms: Implications for biofuels, C. Chou, Francis E. Jenney Jr., M. W. Adams, and R. M. Kelly
Variation of the synarcual in the California Ray, Raja inornata (Elasmobranchii: Rajidae), Kerin M. Claeson
The occipital region in the basal bony fish Erpetoichthys calabaricus (Actinopterygii: Cladistia), Kerin M. Claeson and James W. Hagadorn
Anatomy of the very tiny: First description of the head skeleton of the rare South American catfish sarcoglanis simplex (Siluriformes: Trichomycteridae), Kerin M. Claeson, James W. Hagadorn, Kyle Luckenbill, and John G. Lundberg
Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysis, W. B. Daviss, N. C. Patel, A. S. Robb, M. P. McDermott, O. G. Bukstein, W. E. Pelham Jr., D. Palumbo, P. Harris, Katy E. Tresco, and et al.
Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARa with clofibrate, Shashikiran Donthamsetty, Vishakha Bhave, Mayarranjan S. Mitra, John R. Latendresse, and Harihara M. Mehendale
Consultation Relational Processes and Outcomes for Students With ADHD, William P. Erchul, George J. Dupaul, Megan S. Bennett, Priscilla F. Grissom, Asha K. Jitendra, Katy E. Tresco, Robert J. Volpe, Rosemary E. Vile Junod, Lizette M. Flammer-Rivera, and Mark C. Mannella
Inhibition of expression of anti-apoptotic protein Bcl-2 and induction of cell death in radioresistant human prostate adenocarcinoma cell line (PC-3) by methyl jasmonate, Daniel Ezekwudo, Rangaiah Shashidharamurthy, Dilip Devineni, Erica Bozeman, Ravi Palaniappan, and Periasamy Selvaraj
Higher magnitude cash payments improve research follow-up rates without increasing drug use or perceived coercion, David Festinger, K. Dugosh, J. Croft, and P. Arabia
Clinical Psychology: Integrating Science and Practice, Arthur Freeman; Stephanie H, Felgoise; and Denise D. Davis
A comparison of Swedenborg's and Sutherland's descriptions of brain, dural membrane and cranial bone motion, David B. Fuller
Swedenborg’s Brain and Sutherland’s Cranial Concept, David B. Fuller
Tracking and ablating subpopulations of epiblast cells in the chick embryo, Jacquelyn Gerhart, Christine Neely, J. Pfautz, and Mindy George-Weinstein
Calcineurin inhibition and development: Insights from research models, Jennifer L. Gooch
Calcium-Activated Chloride Current Contributes to Action Potential Alternations in Left Ventricular Hypertrophy Rabbit, Donglin Guo, Lindon H. Young, Chinmay Patel, Zhen Jiao, Ying Wu, Tengxian Liu, Peter R. Kowey, and Gan-Xin Yan
Differential Ability Scales – Second Edition (Neuro)psychological Predictors of Math Performance for Typical Children and Children with Math Disabilities, James B. Hale, Catherine A. Fiorello, Ron Dumont, John O. Willis, Christopher Rackley, and Collin Elliott
To the point: medical education review of the role of simulators in surgical training, M. Hammoud, F. Nuthalapty, A. R. Goepfert, P. M. Casey, S. Emmons, E. L. Espey, Joseph M. Kaczmarczyk, N. T. Katz, J. J. Neutens, and E. G. Peskin
Translating neuronal activity into dendrite elaboration: Signaling to the nucleus, Lori Redmond Hardy
ERK mediates activity dependent neuronal complexity via sustained activity and CREB-mediated signaling, Seungshin Ha and Lori Redmond Hardy
Disrupted intercalated discs: Is kindlin-2 required?, Cathy J. Hatcher and Craig T. Basson
Radiographic Evaluation of Bones and Joints in Mucopolysaccharidosis I and VII Dogs after Neonatal Gene Therapy, Ramin Sedaghat Herati, Van W. Knox, Patricia O'Donnell, Marina D'Angelo, Mark E. Haskins, and Katherine P. Ponder
Internet access to Salvia divinorum: Implications for policy, prevention, and treatment, V. Hoover, D. Marlowe, N. Patapis, David Festinger, and R. Forman
Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-Activated K+ channels, John D. Imig, Christiana Dimitropoulou, D. Sudarshan Reddy, Richard E. White, and John R. Falck
Hydrogenases of the model hyperthermophiles, Francis E. Jenney Jr. and M. W. Adams
The impact of extremophiles on structural genomics (and vice versa), Francis E. Jenney Jr. and M. W. Adams
Enhancing academic achievement for children with attention-deficit hyperactivity disorder: Evidence from school-based intervention research, A. K. Jitendra, George J. Dupaul, F. Someki, and Katy E. Tresco
Flexibility within Fidelity, Philip C. Kendall, Elizabeth A. Gosch, Jami M. Furr, and Erica Sood
Cognitive-Behavioral Therapy for Anxiety Disordered Youth: A Randomized Clinical Trial Evaluating Child and Family Modalities, Philip C. Kendall, Jennifer L. Hudson, Elizabeth A. Gosch, Ellen C. Flannery-Schroeder, and Cynthia Suveg
Targeting Performance Dimensions in Sequence According to the Instructional Hierarchy: Effects on Children's Math Work Within a Self-Monitoring Program, Amanda L. Lannie and Brian K. Martens
Perceptions of Medicare Part D enrollees about pharmacists and their role as providers of medication therapy management, Anandi V. Law, Mark P. Okamoto, and Brock Kelly
Mental Health in the Classroom: a Community Service, Teacher-Training Project., Sarah Levin Allen, C. Riggs Romaine, and K. Hoffman
CaMKIIß binding to stable F-actin in vivo regulates F-actin filament stability, Yuchih Lin and Lori Redmond Hardy
Morphogenesis and regulation of Bergmann glial processes during Purkinje cell dendritic spine ensheathment and synaptogenesis, Jocelyn Lippman-Bell, T. Lordkipanidze, M. E. Buell, S. O. Yoon, and A. Dunaevsky
An effectiveness trial of contingency management in a felony preadjudication drug court, D. Marlowe, David Festinger, K. Dugosh, P. Arabia, and K. Kirby
Postpartum Thyroid Measures and Depressive Symptomology: A Pilot Study, Sarah J. Breese McCoy, J. Martin Beal, Mark E. Payton, Audra L. Stewart, Ariana M. DeMers, and Gary H. Watson
Atrial fibrillation and other clinical manifestations of altered TBX5 dosage in typical holt-oram syndrome, Deborah A. McDermott, Craig T. Basson, and Cathy J. Hatcher
Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs, T. Miyahara, K. Hamanaka, D. S. Weber, Mircea Anghelescu, J. R. Frost, J. A. King, and J. C. Parker
Predicting Rheumatoid Arthritis Risk in Adults With Undifferentiated Arthritis, Eugene Mochan and Mark H. Ebell
Modifying an Evidence-Based Summer Treatment Program for Use in a Summer School Setting, Briannon C. O'Connor, Katy E. Tresco, William E. J. R. Pelham, Anne Ryan, Nicole C. Bycina, Maggie Hoeltke, Pamela McGarvey, and Kelly Ziegler
Clonidine for attention-deficit/hyperactivity disorder: I. Efficacy and tolerability outcomes, D. R. Palumbo, F. R. Sallee, W. E. Pelham Jr., O. G. Bukstein, W. B. Daviss, M. P. McDermott, L. Burrows-MacLean, P. Como, Katy E. Tresco, and et al.
Withaferin A induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes, Heajin Park, Srujana Rayalam, Mary Anne Della-Fera, Suresh Ambati, Jeongyeh Yang, and Clifton A. Baile
Combined effects of genistein, quercetin, and resveratrol in human and 3T3-L1 adipocytes, Heajin Park, Jeongyeh Yang, Suresh Ambati, Mary Anne Della-Fera, Dorothy B. Hausman, Srujana Rayalam, and Clifton A. Baile
The comparison study on effects of water-soluble components of fine particulate matter on vasomotor functions in aortas from rats after exposure in different time, Gang Qin, Ming-sheng Zhang, Desuo Wang, Yue-suo Liang, Hong-mei Yao, Shou-gan Qi, and Ji-yuan Lu
Enhanced effects of 1,25(OH)"2D"3 plus genistein on adipogenesis and apoptosis in 3T3-L1 adipocytes, Srujana Rayalam, Mary Anne Della-Fera, Suresh Ambati, Jeongyeh Yang, Heajin Park, and Clifton A. Baile
Phytochemicals and regulation of the adipocyte life cycle, Srujana Rayalam, Mary Anne Della-Fera, and Clifton A. Baile
A putative role for apelin in the etiology of obesity, Srujana Rayalam, Mary Anne Della-Fera, Paul A. Krieg, Christopher M. Cox, Allan Robins, and Clifton A. Baile
Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes, Srujana Rayalam, Jeongyeh Yang, Suresh Ambati, Mary Anne Della-Fera, and Clifton A. Baile
Patterns of Correlation and Covariation of Anthropoid Distal Forelimb Segments Correspond to Hoxd Expression Territories, Philip L. Reno, Melanie A McCollum, Martin J Cohn, Richard S Meindl, Mark Hamrick, and C Owen Lovejoy
Extreme makeover: The case of a young adult man with severe ADHD, Bradley M. Rosenfield, J. R. Ramsay, and A. L. Rostain
Chlamydophila (Chlamydia) pneumoniae promotes Ab 1-42 amyloid processing in Neuronal Cells: A Pathogenic Trigger for Alzheimer's Disease, Elizabeth K. Ruszak, Karen C. McCarthy, Marcus G. Bell, Brian J. Balin, and Denah M. Appelt
Debt Control for Young DOs, Matthew Schure
Custom designing therapeutic cancer vaccines. Delivery of immunostimulatory molecule adjuvants by protein transfer, Periasamy Selvaraj, A. Yerra, L. Tien, and Rangaiah Shashidharamurthy
Extravasations and emigration of neutrophils to the inflammatory site depend on the interaction of immune-complex with FcY receptors and can be effectively blocked by decoy FcY receptors, Rangaiah Shashidharamurthy, Randolph A. Hennigar, Sebastian Fuchs, Purani Palaniswami, Melanie Sherman, and Periasamy Selvaraj
End-product pathways in the xylose fermenting bacterium, Thermoanaerobacterium saccharolyticum, A. Joe Shaw, Francis E. Jenney Jr., M. W. Adams, and L. R. Lynd
Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus, Kenneth S. Shindler, Lawrence C. Kenyon, Mahasweta Dutt, Susan T. Hingley, and Jayasri Das Sarma
Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease: Implications for the Mucopolysaccharidoses and Other Connective Tissue Diseases, Calogera M. Simonaro, Marina D'Angelo, Xingxuan He, Efrat Eliyahu, Nataly Shtraizent, Mark E. Haskins, and Edward H. Schuchman
Does interferon use prior to liver transplant influence hepatitis C outcomes following transplantation?, Gregory Smallwood; Renee Devine; Carlos Fasola; A, C, Stieber; and Thomas Heffron
Coexistence of Tumid Lupus Erythematosus with Systemic Lupus Erythematosus and Discoid Lupus Erythematosus: A Report of Two Cases of Tumid Lupus, Jennifer Stead, Catherine Headley, Michael Ioffreda, Carrie Kovarik, and Victoria Werth
Mechanisms Related to the Cardioprotective Effects of Protein Kinase C Epsilon (PKC Epsilon) Peptide Activator or Inhibitor in Rat Ischemia/Reperfusion Injury, Jane Chun-wen Teng, Helen Kay, Qian Chen, Jovan S Adams, Christopher Grilli, Giuseppe Guglielmello, Christopher Zambrano, Samuel Krass, Adrian Bell, and Lindon H. Young
Double jeopardy: Child and school characteristics that predict aggressive-disruptive behavior in first grade, Duane E. Thomas, K. L. Bierman, Celine I. Thompson, and C. J. Powers
Ethnicity, Cognitive Styles, and Math Achievement: Variability within African-American Post-Secondary Students, Yuma I. Tomes
Academic Interventions for Students With ADHD: Predictors of Achievement Outcomes, Katy E. Tresco, George J. Dupaul, and Asha K. Jitendra
Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry, Xinyu Wang, Jihai Pang, Robert A. Newman, Sean M. Kerwin, Phillip D. Bowman, and Salomon Stavchansky
Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1, Xinyu Wang, Salomon Stavchansky, Baiteng Zhaoa, James A. Bynum, Sean M. Kerwin, and Phillip D. Bowman
HIV testing and prevention for older adults: Is the office the proper setting for discussion?, Ilene Warner-Maron
Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin, Jeongyeh Yang, Mary Anne Della-Fera, Srujana Rayalam, Suresh Ambati, Diane L. Hartzell, Heajin Park, and Clifton A. Baile
Enhanced effects of xanthohumol plus honokiol on apoptosis in 3T3-L1 adipocytes, Jeongyeh Yang, Mary Anne Della-Fera, Srujana Rayalam, and Clifton A. Baile
Role of phosphodiesterases in modulation of BKCa channels in hypertensive pulmonary arterial smooth muscle, Shu Zhu, Richard E. White, and Scott A. Barman
Submissions from 2007
Transcriptomics, Proteomics, and Structural Genomics of Pyrococcus Furiosus, M. W. Adams, Francis E. Jenney Jr., C. Chou, S. Hamilton-Brehm, F. L. Poole, K. R. Shockley, S. Tachdjian, and R. M. Kelly
Ectopic expression of the homeobox gene Cux-1 rescues calcineurin inhibition in mouse embryonic kidney cultures, N. I. Alcalay, J. G. Brantley, M. Sharma, Jennifer L. Gooch, and G. B. Vanden Heuvel