The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.

The PCOM Scholarly Works repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, book chapters, datasets, and unpublished works by faculty and staff at PCOM's Philadelphia, Georgia, and South Georgia campuses.

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Submissions from 2009

Specification of the cardiac conduction system by transcription factors, Cathy J. Hatcher and Craig T. Basson

Successful outcome after early combined liver and en bloc-kidney transplant in an infant with primary hyperoxaluria type 1: A case report, Thomas Heffron, John Rodriguez, Carlos G. Fasola, Katherine Casper, Todd Pillen, Gregory Smallwood, Barry Warshaw, and Rene Romero

Delayed Salicylate Toxicity with Undetectable Initial Levels after Large-Dose Aspirin Ingestion, Joseph Herres, Danielle Ryan, and Matthew Salzman

Robust, High-Throughput Solution Structural Analyses by Small Angle X-Ray Scattering (SAXS), Greg L. Hura, Angeli L. Menon, Michal Hammel, Robert P. Rambo, Farris L. Poole, Susan E. Tsutakawa, Francis E. Jenney, Scott Classen, Kenneth A. Frankel, Robert C. Hopkins, Sung-Jae Yang, Joseph W. Scott, Bret D. Dillard, Michael W. W. Adams, and John A. Tainer

Adoption and Safe Families Act State Statutes Regarding Parents with Mental Illnesses: A Review and Targeted Intervention, Katy Kaplan, Petra Kottsieper, Jeniece Scott, Mark S. Salzer, and Phyllis Solomon

TGF-β upregulation drives tertiary lymphoid organ formation and kidney dysfunction in calcineurin A-α heterozygous mice, F. M. Kelly, R. N. Reddy, B. R. Roberts, S. Gangappa, I. R. Williams, and Jennifer L. Gooch

Topographic features retained after antibiotic modification of Ti alloy surfaces: Retention of topography with attachment of antibiotics, C. Ketonis, J. Parvizi, Christopher S. Adams, I. M. Shapiro, and N. J. Hickok

Clinical Performance of the TRUE2go Blood Glucose System-A Novel Integrated System for Meter and Strips, Mark S. Kipnes, Hal Joseph, Harry J. Morris, Jason Manko, and Douglas E. Bell

Myosin-II Negatively Regulates minor process extension and the temporal development of neuronal polarity, K. M. Kollins, J. Hu, Yueqiao Huang, and G. Gallo

Experiential knowledge of serious mental health problems: One clinician and academic's perspective, Petra Kottsieper

Correlation between an email based board review program and American Board of Pediatrics General Pediatrics Certifying Examination scores., E. E. Langenau, J. Fogel, H. A. Schaeffer, and Wilson

Ready, Willing, and Able to Provide MTM Services? A Survey of Community Pharmacists in the USA, Anandi V. Law, Mark P. Okamoto, and Kelly Brock

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Overexpression of truncated ERG from TMPRSS2-ERG fusion and prostate cancer development , Melanie Leong, Wenfeng Shi, Jun Tian, Ellen Cho, Abbas Raza, Saquib A. Siddiqi, Abdulhafez Selim, Hanchun Chen, and Dianzheng Zhang

Neuronal CaMKII acts as a structural kinase, Yuchih Lin and Lori Redmond Hardy

Effects of MS23 on KCl-, a-adrenoceptor agonists- and U46619-induced contractions of arteries isolated from rat different organs, Y. Liu, Ming-sheng Zhang, Desuo Wang, D. B. Liu, W. X. Xue, L. G. Niu, and Y. Q. Liang

Activation of glycogen synthase kinase-3ß is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex, Yan-Chun Li, Dong Xi, Joy Roman, Yueqiao Huang, and Wen-Jun Gao

3D electron microscopic reconstruction of segments of rat cerebellar Purkinje cell dendrites receiving ascending and parallel fiber granule cell synaptic inputs, Huo Lu, Angelica V. Esquivel, and James M. Bower

Physiologically evoked neuronal current MRI in a bloodless turtle brain: Detectable or not?, Qingfei Luo, Huo Lu, Hanbing Lu, David Senseman, Keith Worsley, Yihong Yang, and Jia-Hong Gao

Middle Adulthood and Aging, Burton Mach and D. Baron

Adaptive interventions may optimize outcomes in drug courts: A pilot study, D. Marlowe, David Festinger, P. Arabia, K. Dugosh, and K. Benasutti

Reassessment of the Cranial Characters of Glossotherium and Paramylodon (Mammalia: Xenarthra: Mylodontidae), Robert McAfee

Applying an Executive Function Framework in Educational Therapy, George McCloskey

Clinical applications I: A neuropsychological approach to interpretation of the WAIS-IV and the use of the WAIS-IV in learning disability assessments, George McCloskey

The WISC-IV Integrated, George McCloskey

Executive functions and emotional disturbance, George McCloskey, Joseph Hewitt, Julie N. Henzel, and Eleazar Eusebio

Assessment and intervention for executive function difficulties, George McCloskey, Lisa A. Perkins, and Bob Van Divner

Reducing Disruptive Behavior in an Urban School Cafeteria: An Extension of the Good Behavior Game, Barry L. McCurdy, Amanda L. Lannie, and Ernesto Barnabas

Novel multiprotein complexes identified in the hyperthermophilic archaeon pyrococcus furiosus by non-denaturing fractionation of the native proteome, A. L. Menon, F. L. Poole II, A. Cvetkovic, S. A. Trauger, E. Kalisiak, J. W. Scott, S. Shanmukh, J. Praissman, Francis E. Jenney Jr., and et al.

Current Diagnosis and Treatment [Media Review], Bohdan Minczak

The underrecognized epilepsy spectrum: The effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production, Mark Mintz, Daniel Legoff, Jean Scornaienchi, Micah Brown, Sarah Levin Allen, Pnina Mintz, and Cathy Smith

Risk-Assessment Tools for Detecting Undiagnosed Diabetes., Eugene Mochan and Mark H. Ebell

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy, Heather L. Montie, Maria Cho, Latia Holder, Yuhong Liu, Andrey S. Tsvetkov, Steven Finkbeiner, and Diane E. Merry

Autophagy and access: Understanding the role of androgen receptor subcellular localization in SBMA, Heather L. Montie and Diane E. Merry

Problem Solving Skills Predict Quality of Llife and Psychological Morbidity in ALS Caregivers, Virginia Murphy, Stephanie H. Felgoise, Susan M. Walsh, and Zachary Simmons

An 11-Year-Old Boy with a Patella Fracture, Jason A. Nydick, Martin J. Herman, and Jean-Pierre de Chadarévian

Regression Analysis for Prediction: Understanding the Process, Phillip B. Palmer and Dennis G O'Connell

Genistein inhibits differentiation of primary human adipocytes, Heajin Park, Mary Anne Della-Fera, Dorothy B. Hausman, Srujana Rayalam, Suresh Ambati, and Clifton A. Baile

Thiazolidinediones and Congestive Heart Failure: A Judicious Balance of Risks and Benefits, Rujul R. Patel

Functional interactions between distinct sodium channel cytoplasmic domains through the action of calmodulin, F. Potet, B. Chagot, Mircea Anghelescu, P. Viswanathan, S. J. Stepanovic, S. Kuperschmidt, W. J. Chazin, and J. R. Balser

School-based interventions for students with attention-deficit/ hyperactivity disorder, T. J. Power, Katy E. Tresco, and M. C. Cassano

Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes, Srujana Rayalam, Jeongyeh Yang, Mary Anne Della-Fera, Heajin Park, Suresh Ambati, and Clifton A. Baile

Patient note fabrication and consequences of unprofessional behavior in a high-stakes clinical skills licensing examination, J. M. Sandella, W. L. Roberts, L. A. Gallagher, J. R. Gimpel, E. E. Langenau, and J. R. Boulet

Soy phytoestrogens are neuroprotective against stroke-like injury in vitro, D. A, Schreifhofer and Lori Redmond Hardy

Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fcγ receptor CD32A, Rangaiah Shashidharamurthy, Fang Zhang, Aaron Amano, Aparna Kamat, Ravichandran Panchanathan, Daniel Ezekwudo, Cheng Zhu, and Periasamy Selvaraj

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Repressive effects of resveratrol on androgen receptor transcriptional activity, Wenfeng Shi, Melanie Leong, Ellen Cho, Joseph Farrell, Hanchun Chen, Jun Tian, and Dianzheng Zhang

A 2-base pair deletion polymorphism in the partial duplication of the a7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia, Melissa L. Sinkus, Michael Lee, Judith Gault, Judith Logel, Margaret Short, Robert Freedman, Susan L. Christian, Jennifer Lyon, and Sherry Leonard

Cognitive-Behavioral Therapy for Anxiety-Disordered Youth: Secondary Outcomes from a Randomized Clinical Trial Evaluating Child and Family Modalities, Cynthia Suveg, Jennifer L. Hudson, Gene Brewer, Ellen C. Flannery-Schroeder, Elizabeth A. Gosch, and Philip C. Kendall

HLA Class I (ABC) Upregulation on Peripheral Blood CD3+/CD8+ T Lymphocyte Surface is a Potential Predictor of Acute Rejection in Renal Transplantation, Jun Tian, Wen-Feng Shi, Lu-Wei Zhang, Nan Lu, Xian-Quan Cui, Wan-Hua Xian, Huai-Bin Sun, En-Gang Li, Li-Na Geng, Dianzheng Zhang, and Xiong Zou

Effect of functional end groups of silane self-assembled monolayer surfaces on apatite formation, fibronectin adsorption and osteoblast cell function, G. K. Toworfe, S. Battacharyya, R. J. Composto, Christopher S. Adams, I. M. Shapiro, and P. Ducheyne

Osteopathic Medical Graduates in ACGME Residencies: A Threat to the Core Philosophy and Distinctiveness of Osteopathic Medicine, Kenneth J. Veit

TJ-41 Induces apoptosis and potentiates the apoptotic effects of 5-FU in breast cancer cell lines, Suresh Volate, Robert Hudson, Desuo Wang, Stephanie Muga, and Michael Wargovich

Special topic, research brief, R. J. Volpe, George J. DuPaul, A. K. Jitendra, and Katy E. Tresco

Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats, Xinyu Wang, Jihai Pang, Jacqueline A. Maffucci, Devandra S. Patel, Robert A. Newman, Sean M. Kerwin, Phillip D. Bowman, and Salomon Stavchansky

A Community Health Center's Diabetes Project: A Strategy to Reduce Health Disparities, Shoshana Wernick, Rhonda Lewis-Moss, Mary Williams, and Beverly White

HPLC/MS/MS analysis of 3-carbamyl-4-methylpyrrole analog MNP001, a highly potent antihypertensive agent, in rat plasma, Binfeng Xia, Ting Wang, Laura M. Fox, and Desuo Wang

Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail, Jeongyeh Yang, Mary Anne Della-Fera, Srujana Rayalam, Heajin Park, Suresh Ambati, Dorothy B. Hausman, Diane L. Hartzell, and Clifton A. Baile

Octanoate and decanoate induce apoptosis in 3T3-L1 adipocytes, Jeongyeh Yang, Srujana Rayalam, Mary Anne Della-Fera, Suresh Ambati, and Clifton A. Baile

Pathogenesis and therapy of autoimmunity-induced dilated cardiomyopathy, P. Zhao, Avadhesh C. Sharma, and J. Ren

Mutation of protein kinase C phosphorylation site S1076 on α-subunits affects BKCa channel activity in HEK-293 cells, Shu Zhu, Darren D. Browning, Richard E. White, David Fulton, and Scott A. Barman

Submissions from 2008

The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection, V. Antoci Jr., Christopher S. Adams, J. Parvizi, H. M. Davidson, R. J. Composto, T. A. Freeman, E. Wickstrom, P. Ducheyne, D. Jungkind, and I. M. Shapiro

Maze Suite 1.0: A complete set of tools to prepare, present, and analyze navigational and spatial cognitive neuroscience experiments, Hasan Ayaz and Sarah Levin Allen

Chlamydophila pneumoniae and the Etiology of Late-Onset Alzheimer's Disease, Brian J. Balin, Christopher Scott Little, Christine J. Hammond, Denah M. Appelt, Judith A. Whittum-Hudson, Hervé C. Gérard, and Alan P. Hudson

Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury, Vishakha Bhave, Shashikiran Donthamsetty, John R. Latendresse, and Harihara M. Mehendal

Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2, Vishakha Bhave, Shashikiran Donthamsetty, John R. Latendresse, Levan Muskhelishvili, and Harihara M. Mehendale

Hydrogenesis in hyperthermophilic microorganisms: Implications for biofuels, C. Chou, Francis E. Jenney Jr., M. W. Adams, and R. M. Kelly

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Variation of the synarcual in the California Ray, Raja inornata (Elasmobranchii: Rajidae), Kerin M. Claeson

The occipital region in the basal bony fish Erpetoichthys calabaricus (Actinopterygii: Cladistia), Kerin M. Claeson and James W. Hagadorn

Anatomy of the very tiny: First description of the head skeleton of the rare South American catfish sarcoglanis simplex (Siluriformes: Trichomycteridae), Kerin M. Claeson, James W. Hagadorn, Kyle Luckenbill, and John G. Lundberg

Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysis, W. B. Daviss, N. C. Patel, A. S. Robb, M. P. McDermott, O. G. Bukstein, W. E. Pelham Jr., D. Palumbo, P. Harris, Katy E. Tresco, and et al.

Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARa with clofibrate, Shashikiran Donthamsetty, Vishakha Bhave, Mayarranjan S. Mitra, John R. Latendresse, and Harihara M. Mehendale

Consultation Relational Processes and Outcomes for Students With ADHD, William P. Erchul, George J. Dupaul, Megan S. Bennett, Priscilla F. Grissom, Asha K. Jitendra, Katy E. Tresco, Robert J. Volpe, Rosemary E. Vile Junod, Lizette M. Flammer-Rivera, and Mark C. Mannella

Inhibition of expression of anti-apoptotic protein Bcl-2 and induction of cell death in radioresistant human prostate adenocarcinoma cell line (PC-3) by methyl jasmonate, Daniel Ezekwudo, Rangaiah Shashidharamurthy, Dilip Devineni, Erica Bozeman, Ravi Palaniappan, and Periasamy Selvaraj

Higher magnitude cash payments improve research follow-up rates without increasing drug use or perceived coercion, David Festinger, K. Dugosh, J. Croft, and P. Arabia

Clinical Psychology: Integrating Science and Practice, Arthur Freeman; Stephanie H, Felgoise; and Denise D. Davis

A comparison of Swedenborg's and Sutherland's descriptions of brain, dural membrane and cranial bone motion, David B. Fuller

Swedenborg’s Brain and Sutherland’s Cranial Concept, David B. Fuller

Tracking and ablating subpopulations of epiblast cells in the chick embryo, Jacquelyn Gerhart, Christine Neely, J. Pfautz, and Mindy George-Weinstein

Calcineurin inhibition and development: Insights from research models, Jennifer L. Gooch

Calcium-Activated Chloride Current Contributes to Action Potential Alternations in Left Ventricular Hypertrophy Rabbit, Donglin Guo, Lindon H. Young, Chinmay Patel, Zhen Jiao, Ying Wu, Tengxian Liu, Peter R. Kowey, and Gan-Xin Yan

Differential Ability Scales – Second Edition (Neuro)psychological Predictors of Math Performance for Typical Children and Children with Math Disabilities, James B. Hale, Catherine A. Fiorello, Ron Dumont, John O. Willis, Christopher Rackley, and Collin Elliott

To the point: medical education review of the role of simulators in surgical training, M. Hammoud, F. Nuthalapty, A. R. Goepfert, P. M. Casey, S. Emmons, E. L. Espey, Joseph M. Kaczmarczyk, N. T. Katz, J. J. Neutens, and E. G. Peskin

Translating neuronal activity into dendrite elaboration: Signaling to the nucleus, Lori Redmond Hardy

ERK mediates activity dependent neuronal complexity via sustained activity and CREB-mediated signaling, Seungshin Ha and Lori Redmond Hardy

Disrupted intercalated discs: Is kindlin-2 required?, Cathy J. Hatcher and Craig T. Basson

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Radiographic Evaluation of Bones and Joints in Mucopolysaccharidosis I and VII Dogs after Neonatal Gene Therapy, Ramin Sedaghat Herati, Van W. Knox, Patricia O'Donnell, Marina D'Angelo, Mark E. Haskins, and Katherine P. Ponder

Internet access to Salvia divinorum: Implications for policy, prevention, and treatment, V. Hoover, D. Marlowe, N. Patapis, David Festinger, and R. Forman

Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-Activated K+ channels, John D. Imig, Christiana Dimitropoulou, D. Sudarshan Reddy, Richard E. White, and John R. Falck

Hydrogenases of the model hyperthermophiles, Francis E. Jenney Jr. and M. W. Adams

The impact of extremophiles on structural genomics (and vice versa), Francis E. Jenney Jr. and M. W. Adams

Enhancing academic achievement for children with attention-deficit hyperactivity disorder: Evidence from school-based intervention research, A. K. Jitendra, George J. Dupaul, F. Someki, and Katy E. Tresco

Flexibility within Fidelity, Philip C. Kendall, Elizabeth A. Gosch, Jami M. Furr, and Erica Sood

Cognitive-Behavioral Therapy for Anxiety Disordered Youth: A Randomized Clinical Trial Evaluating Child and Family Modalities, Philip C. Kendall, Jennifer L. Hudson, Elizabeth A. Gosch, Ellen C. Flannery-Schroeder, and Cynthia Suveg

Targeting Performance Dimensions in Sequence According to the Instructional Hierarchy: Effects on Children's Math Work Within a Self-Monitoring Program, Amanda L. Lannie and Brian K. Martens

Perceptions of Medicare Part D enrollees about pharmacists and their role as providers of medication therapy management, Anandi V. Law, Mark P. Okamoto, and Brock Kelly

Mental Health in the Classroom: a Community Service, Teacher-Training Project., Sarah Levin Allen, C. Riggs Romaine, and K. Hoffman

CaMKIIß binding to stable F-actin in vivo regulates F-actin filament stability, Yuchih Lin and Lori Redmond Hardy

Morphogenesis and regulation of Bergmann glial processes during Purkinje cell dendritic spine ensheathment and synaptogenesis, Jocelyn Lippman-Bell, T. Lordkipanidze, M. E. Buell, S. O. Yoon, and A. Dunaevsky

An effectiveness trial of contingency management in a felony preadjudication drug court, D. Marlowe, David Festinger, K. Dugosh, P. Arabia, and K. Kirby

Postpartum Thyroid Measures and Depressive Symptomology: A Pilot Study, Sarah J. Breese McCoy, J. Martin Beal, Mark E. Payton, Audra L. Stewart, Ariana M. DeMers, and Gary H. Watson

Atrial fibrillation and other clinical manifestations of altered TBX5 dosage in typical holt-oram syndrome, Deborah A. McDermott, Craig T. Basson, and Cathy J. Hatcher