The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.
The PCOM Scholarly Works repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, book chapters, datasets, and unpublished works by faculty and staff at PCOM's Philadelphia, Georgia, and South Georgia campuses.
Submissions from 2012
On researching the agency of youth: Moving beyond traditional theorizing. Commentary on Nsamenang, Celine I. Thompson
In vivo iontophoretic delivery of salmon calcitonin across microporated skin, Viswatej Vemulapalli, Yun Bai, Haripriya Kalluri, Anushree Herwadkar, Hyun Kim, Shawn P. Davis, Phil M. Fridin, and Ajay K. Banga
Streamlining Undergraduate Medical Education: Something We Should Have Discussed Decades Ago, Mark Vila
The West Virginia Prescription Drug Abuse Quitline: Challenges and Lessons Learned from Running a Remote Quitline, Rebecca J. White, Keith J. Zullig, Laura Lander, Clara Shockley, Robert Pack, and Carl Sullivan
Cooperative roles of BDNF expression in neurons and schwann cells are modulated by exercise to facilitate nerve regeneration, J. C. Wilhelm, Mei Xu, D. Cucoranu, S. Chmielewski, T. Holmes, K. S. Lau, G. J. Bassell, and A. W. English
Cooperative Roles of BDNF Expression in Neurons and Schwann Cells are Modulated by Exercise to Facilitate Nerve Regeneration, Jennifer C. Wilhelm, Mei Xu, Delia Cucoranu, Sarah E. Chmielewski, Tiffany M. Holmes, Kelly S. Lau, Gary J. Bassell, and Arthur W. English
Non-Invasive Ventilation and Gastrostomy May Not Impact Overall Quality of Life in Patients with ALS, Kristen Zamietra, Erik B. Lehman, Stephanie H. Felgoise, Susan M. Walsh, Helen E. Stephens, and Zachary Simmons
Non-invasive ventilation and gastrostomy may not impact overall quality of life in patients with ALS, Kristen Zamietra, Erik B. Lehman, Stephanie S. Felgoise, Helen E. Stephens, and Zachary Simmons
Allergic reaction to peripheral nerve stimulator, L. Zhou, A. Lee, R. Schaffner, and Gerald E. Dworkin
Submissions from 2011
Oseltamivir use in psychiatric inpatients taking clozapine: effect on neuropsychiatric events, Shari N. Allen, Tammie Lee Demler, Eileen Trigoboff, and Lewis A. Opler
The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of a7*nAChR function, Tanguy Araud, Sharon Graw, Ralph Berger, Michael Lee, Estele Neveu, Daniel Bertrand, and Sherry Leonard
Effect of resveratrol on fat mobilization, Clifton A. Baile, Jeongyeh Yang, Srujana Rayalam, Diane L. Hartzell, Chingyi Lai, Charlotte Andersen, and Mary Anne Della-Fera
Evidence for an Infectious Etiology in Alzheimer's Disease, Brian J. Balin PhD, Christine Hammond, C. Scott Little PhD, Denah Appelt, and Susan Hingley
Analysis of Chlamydia pneumoniae-infected monocytes following incubation with a novel peptide, acALY18, implicates the inflammasome in clearance of infection, Brian J. Balin, James D. Thacker, Charles Lim, Corey M. Caruthers, Susan T. Hingley, Juliana Zoga, and Denah M. Appelt
Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice, Shoshana M. Bartell, Srujana Rayalam, Suresh Ambati, Dhanunjaya Gaddam, Diane L. Hartzell, Mark Hamrick, Jinxiong She, Mary Anne Della-Fera, and Clifton A. Baile
Analysis of Chlamydia pneumoniae and AD-like Pathology in the Brains of BALB/c Mice Following Direct Intra-cranial Infection, Jessica Rachel Barton, Christine J. Hammond, Amy L. Brady, Denah M. Appelt, Brian J. Balin, and Christopher Scott Little
MRSA Otorrhea: A Case Series and Review of the Literature, Katherine M. Baugher, Troy Sommers Hemme, Mary Hawkshaw, and Robert T. Sataloff
Flawed science is not evidence-based osteopathic medicine, Murray R. Berkowitz
Increasing the number of osteopathic graduate medical education programs-"The time has come", Murray R. Berkowitz
Osteopathic scholarship, research and publication, Murray R. Berkowitz
Bipolar Affective Disorder in Young People: A Review, Bettina Bernstein
Secretory phospholipase A 2-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2, Vishakha Bhave, Shashikiran Donthamsetty, John R. Latendresse, Michael L. Cunningham, and Harihara M. Mehendale
Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo, Vishakha Bhave, Shirish Paranjpe, William C. Bowen, Shashikiran Donthamsetty, Aaron W. Bell, Jaspal S. Khillan, and George K. Michalopoulos
A novel microparticulate vaccine for melanoma cancer using transdermal delivery, Tuhin Bhowmik, Bernadette D'Souza, Rangaiah Shashidharamurthy, Carl Oettinger, Periasamy Selvaraj, and Martin D'Souza
RhoB Deficiency in Thymic Medullary Epithelium Leads to Early Thymic Atrophy, Arturo Bravo Nuevo, Rebekah O'Donnell, Alexander Rosendahl, Jae Hoon Chung, Laura E Benjamin, and Chikako Odaka
RhoB Loss Prevents Streptozotocin-induced Diabetes and Ameliorates Diabetic Complications in Mice, Arturo Bravo Nuevo, Hikaru Sugimoto, Seema Iyer, Zachary Fallon, Jason M Lucas, Shiva Kazerounian, George C Prendergast, Raghu Kalluri, Nathan I Shapiro, and Laura E Benjamin
Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China, Hanchun Chen, H. Chen, Md. Asaduzzaman Khan, Zhouzhou Rao, Xinxing Wan, Bo Tan, and Dianzheng Zhang
Osteopathic approach to a patient with chronic fatigue syndrome, Anne Chong and Murray R. Berkowitz
Modulation of Myocardial Mitochondrial Mechanisms during severe Polymicrobial Sepsis in the Rat, M. Chopra, H. B. Golden, S. Mullapudi, W. Dowhan, D. E. Dostal, and Avadhesh C. Sharma
Mechanisms involved in apoptosis events contributing to sepsis-induced myocardial dysfunction, M. Chopra and Avadhesh C. Sharma
The synarcual cartilage of batoids with emphasis on the synarcual of Rajidae, Kerin M. Claeson
The skeleton | Cartilaginous Fish Skeletal Anatomy, Kerin M. Claeson and M. N. Dean
Morphology of the anterior vertebral region in elasmobranchs: Special focus, Squatiniformes, Kerin M. Claeson and A. Hilger
Youth Gangs: Reason for Concern, Paul Thomas Clements and Cliff Akiyama
Psychological Health in Patients with ALS is Maintained as Physical Function Declines, Julia Cupp, Zachary Simmons, Arthur Berg, Stephanie H. Felgoise, Susan M. Walsh, and Helen E. Stephens
Nutrition in Medical Education: History, Current Status, and Resources, Farzaneh Daghigh, David J. Vettori, and Jeffrey Harris
Vitamins, Michael J. Deimling
Infection of neuronal cells by Chlamydia pneumoniae and Herpes simplex virus type 1 alters expression of genes associated with Alzheimer’s disease, Morgan M. Devins, Fiora D. Zoga, Brian J. Balin, Denah M. Appelt, and Susan T. Hingley
Demystifying the Millennial Student: A Reassessment in Measures of Character and Engagement in Professional Education, Camille DiLullo, Patricia McGee, and Richard M. Kriebel
Limited Availability of ZB P1 Restricts Axonal mRNA Localization and Nerve Regeneration Capacity, Christopher J. Donnelly, Dianna E. Willis, Mei Xu, Chhavy Tep, Chunsu Jiang, Soonmoon Yoo, N. Carolyn Schanen, Catherine B. Kirn-Safran, Jan van Minnen, Arthur English, Sung Ok Yoon, Gary J. Bassell, and Jeffery L. Twiss
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity, C. J. Donnelly, D. E. Willis, Mei Xu, C. Tep, C. Jiang, and et al.
Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene, Shashikiran Donthamsetty, Vishakha Bhave, Corrine S. Kliment, William C. Bowen, Wendy M. Mars, Aaron W. Bell, Rachel E. Stewart, Anne Orr, Chuanyue Wu, and George K. Michalopoulos
Changes in Self-Reported Drinking Behaviors among US Teenagers Associated with the Introduction of Flavored Malt Beverages: An Interrupted Time Series Quasi-experiment, Jane Z. Dumsha, Robert A. DiTomasso, Frank C. Gomez, Nancy J. Melucci, and Bruce C. Stouch
In the Ether, Out of View: Cyberbullying and Suicide Risk, Terri A. Erbacher PhD
Do research intermediaries reduce perceived coercion to enter research trials among criminally involved substance abusers?, David Festinger, K. Dugosh, J. Croft, P. Arabia, and D. Marlowe
Optimizing Outcomes for GLP-1 Agonists, Jeffrey S. Freeman
Review of Swedenborg’s Paradigm of the Brain, David B. Fuller
Robert C. Fulford, D.O., David B. Fuller
Care at the Close of Life: Evidence and Experience, Katherine E. Galluzzi
Sexuality as Women Age, Katherine E. Galluzzi
The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells, P. S. Ganapathy, Richard E. White, Y. Ha, Bozard B. Renee, P. L. McNeil, Caldwell R. William, S. Kumar, S. M. Black, and S. B. Smith
Retrieval of Inferior Vena Cava Filters after Prolonged Indwelling Time, Franklin Garcia-Godoy, Tara Collins, David Sacks, Steve Vasas, and Babak Sarani
Myo/Nog Cell Regulation of Bone Morphogenetic Protein Signaling in the Blastocyst Is Essential for Normal Morphogenesis and Striated Muscle Lineage Specification, Jacquelyn Gerhart, Victoria L Scheinfeld, Tara Milito, Jessica Pfautz, Christine Neely, Dakota Fisher-Vance, Kelly Sutter, Mitchell Crawford, Karen Knudsen, and Mindy George-Weinstein
Myo/Nog cell regulation of bone morphogenetic protein signaling in the blastocyst is essential for normal morphogenesis and striated muscle lineage specification, Jacquelyn Gerhart, V. Scheinfeld, T. Milito, J. Pfautz, C. Neely, C. Fisher-Vance, K. Sutter, M. Crawford, K. Knudsen, and Mindy George-Weinstein
Self-Assessed Learning Style Correlates to use of Supplemental Learning Materials in an Online Course Management System., Caitlin Halbert, Richard M. Kriebel, Robert Cuzzolino, Patrick Coughlin, and Kerin Fresa-Dillon
Understanding the impact of limb loss in veterans., K. Haldaman and Scott D. Glassman
Facilitating School Reintegration for Children with Traumatic Brain Injury, James B. Hale, Nadine Metro, Jessica Glass Kendorski, Lisa A. Haim, James Whitaker, and Jaime Moldovan
Executive Impairment Determines ADHD Medication Response: Implications for Academic Achievement, James B. Hale, Linda A. Reddy, Margaret Semrud-Clikeman, Lisa A. Hain, James Whitaker, Jessica Morley, Kyle Lawrence, Alex Smith, and Nicole Jones
Financial Analysis in Pharmacy Practice, Keith N. Herist, Brent Rollins, and Matthew Perri
Tethered antibiotics, N. J. Hickok, C. Ketonis, and Christopher S. Adams
Tethered Antiobiotics, N. J. Hickok, C. Ketonis, and Christopher S. Adams
Implementation of a Stroke Alert Protocol in the Emergency Department: A Pilot Study, Carl Hoegerl, Frederick J. Goldstein, and Jennifer Sartorius
Homologous expression of a subcomplex of pyrococcus furiosus hydrogenase that interacts with pyruvate ferredoxin oxidoreductase, R. C. Hopkins, J. Sun, Francis E. Jenney Jr., S. K. Chandrayan, P. M. Mcternan, and M. W. Adams
Reducing the late sodium current improves cardiac function during sodium pump inhibition by ouabain., Kirsten Hoyer, Yejia Song, Desuo Wang, Dillon Phan, James Balschi, Joanne S Ingwall, Luiz Belardinelli, and John C Shryock
To the Point: Medical Education Reviews-Ongoing Call for Faculty Development, Nancy A. Hueppchen, John L. Dalrymple, Maya M. Hammoud, Jodi F. Abbott, Petra M. Casey, Alice W. Chuang, Amie J. Cullimore, Katrina R. Davis, Lorraine Dugoff, Eve L. Espey, Joseph M. Kaczmarczyk, Francis S. Nuthalapaty, Edward Peskin, Archana Pradhan, and Nadine T. Katz
To the point: Medical education reviewsongoing call for faculty development, N. Hueppchen, J. L. Dalrymple, M. M. Hammoud, J. F. Abbott, P. M. Casey, A. W. Chuang, A. Cullimore, K. R. Davis, Joseph M. Kaczmarczyk, and et al.
Sacroiliac joint sparing in a patient with ankylosing spondylitis - An osteopathic approach, Joy Ishii, W. C. Ehrenfeuchter, K. M. Olds, and Murray R. Berkowitz
Eruptive Kaposi Sarcoma: An Unusual Presentation in an HIV-Negative Patient, Mollie M. Jan, Joseph W. Laskas, and Thomas D. Griffin
Vancomycin Bonded to Bone Grafts Prevents Bacterial Colonization, Constantinos Ketonis, Stephanie Barr, Christopher S. Adams, Irving M. Shapiro, Javad Parvizi, and Noreen J. Hickok
Antibacterial Activity of Bone Allografts: Comparison of a New Vancomycin-Tethered Allograft with Allograft Loaded with Adsorbed Vancomycin, Constantinos Ketonis, Stephanie Barr, Irving M. Shapiro, Javad Parvizi, Christopher S. Adams, and Noreen J. Hickok
Anticancer activities of Nigella sativa (Black Cumin), Md. Asaduzzaman Khan, Hanchun Chen, Mousumi Tania, and Dianzheng Zhang
Medicinal chemistry and the pharmacy curriculum., M O Faruk Khan, Michael J. Deimling, and Ashok Philip
Preventing bone loss and weight gain with combinations of vitamin d and phytochemicals, Chingyi Lai, Jeongyeh Yang, Srujana Rayalam, Mary Anne Della-Fera, Suresh Ambati, Richard D. Lewis, Mark W. Hamrick, Diane L. Hartzell, and Clifton A. Baile
Infantile Melanoma-A Triple Threat: Diagnosis and Management, Milena Lambie, Chad Nadler, Paul Glat, Scott Van Duzer, Gregory Halligan, and Evan Geller
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins Using ICP-MS and MS/MS Data, W. Andrew Lancaster, Jeremy L. Praissman, Farris L. Poole, Aleksandar Cvetkovic, Angeli Lal Menon, Joseph W. Scott, Francis E. Jenney, Michael P. Thorgersen, Ewa Kalisiak, Junefredo V. Apon, Sunia A. Trauger, Gary Siuzdak, John A. Tainer, and Michael W. W. Adams
Relationship between standardized patient checklist item accuracy and performing arts experience, E. E. Langenau, D. J. Dowling, C. Dyer, and W. L. Roberts
Competency-based classification of COMLEX-USA cognitive examination test items, E. E. Langenau, G. Pugliano, and W. Roberts
Relationships Between High-Stakes Clinical Skills Exam Scores and Program Director Global Competency Ratings of First-Year Pediatric Residents, E. E. Langenau, G. Pugliano, and W. L. Roberts
Pass/fail patterns of candidates who failed COMLEX-USA level 2-PE because of misrepresentation of clinical findings on postencounter notes, E. E. Langenau and J. M. Sandella
The challenges for physicians of demonstrating continuing competence in the changing world of medical regulation: Osteopathic pediatrician case report, Erik E. Langenau and J. R. Gimpel
How soon can I play after a concussion?, Kate Laramie and Gretchen Fox
Increased Proteolysis, Myosin Depletion, and Atrophic AKT-FOXO Signaling in Human Diaphragm Disuse, Sanford Levine, Chhanda Biswas, Jamil Dierov, Robert J. Barsotti, Joseph B. Shrager, Taitan Nguyen, Seema Sonnad, John C. Kucharchzuk, Larry R. Kaiser, Sunil Singhal, and Murat T. Budak
Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse, S. Levine, C. Biswas, J. Dierov, Robert J. Barsotti, J. B. Shrager, T. Nguyen, S. Sonnad, J. C. Kucharchzuk, L. R. Kaiser, and et.al
HElp3 directly modulates the expression of HSP70 gene in HeLa cells via HAT activity, Fen Li, Jixian Ma, Yu Ma, Yanyan Hu, Shuhuan Tian, Richard E. White, and Guichun Han
Hepatocyte proliferation and hepatomegaly induced by phenobarbital and 1,4-bis [2-(3,5-dichloropyridyloxy)] benzene is suppressed in hepatocyte-targeted glypican 3 transgenic mice, Chihwen Lin, Wendy M. Mars, Shirish Paranjpe, Shashikiran Donthamsetty, Vishakha Bhave, Liangi Kang, Anne Orr, William C. Bowen, Aaron W. Bell, and George K. Michalopoulos
Natural competence in the hyperthermophilic archaeon Pyrococcus furiosus facilitates genetic manipulation: Construction of markerless deletions of genes encoding the two cytoplasmic hydrogenases, G. L. Lipscomb, K. Stirrett, G. J. Schut, F. Yang, Francis E. Jenney Jr., R. A. Scott, M. W. Adams, and J. Westpheling
Identification of Heptapeptides Interacting with IFN-α-Sensitive CML cells, Jia Liu, Hanchun Chen, Zhou-zhou Rao, Md. Asaduzzaman Khan, Xin-Xing Wan, Ai-hua Xu, Nuo Zhang, and Dianzheng Zhang
Genetic Polymorphisms of Metabolic Enzymes-CYP1A1, CYP2D6, GSTM1, and GSTT1, and Gastric Carcinoma Susceptibility, Ya-Ping Luo, Hanchun Chen, Md. Asaduzzaman Khan, Fang-Zhi Chen, Xin-Xing Wan, Bo Tan, Fang-Dan Ou-Yang, and Dianzheng Zhang
Targeting dispositions for drug-involved offenders: A field trial of the Risk and Needs Triage (RANT)â„¢, D. Marlowe, David Festinger, and K. Dugosh
Matching consequences to behavior: Implications of failing to distinguish between noncompliance and nonresponsivity, J. Matejkowski, David Festinger, L. Benishek, and K. Dugosh
Feeding Mechanics and Dietary Implications in the Fossil Sloth Neocnus (Mammalia: Xenarthra: Megalonychidae) from Haiti, Robert McAfee
Rehabilitation of the Pelvis and the Sacroiliac Joint, Darren McAuley
Applying a multilevel interpretive framework with an emphasis on the assessment of executive functions, George McCloskey
Evaluating students with emotional and behavioral concerns, Barry L. McCurdy, Amanda L. Lannie, and Jennifer L. Jeffrey-Pearsall
Neuropsychology of auditory processing disorders, Mark R. McGowan, George McCloskey, Art Maerlender, and James Whitaker
Human-Specific Loss of Regulatory DNA and the Evolution of Human-Specific Traits, Cory Y McLean, Philip L. Reno, Alex A Pollen, Abraham I Bassan, Terence D Capellini, Catherine Guenther, Vahan B Indjeian, Xinhong Lim, Douglas B Menke, Bruce T Schaar, Aaron M Wenger, Gill Bejerano, and David M Kingsley
Detection, advice, and referral to services (DARTS) procedures among clients with public defenders, A Mericle, S. Belenko, and David Festinger
Dynamics of the [4Fe-4S] cluster in pyrococcus furiosus D14C ferredoxin via nuclear resonance vibrational and resonance raman spectroscopies, force field simulations, and density functional theory calculations, D. Mitra, V. Pelmenschikov, Y. Guo, D. A. Case, H. Wang, W. Dong, M. Tan, T. Ichiye, Francis E. Jenney Jr., and et al.
SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA, Heather L. Montie, Richard G. Pestell, and Diane E. Merry
Calcium/calmodulin-dependent protein kinase IV mediates distinct features of basal and activity-dependent dendrite complexity, T. Nagendran and Lori Redmond Hardy