The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.
The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.
Submissions from 2014
Targeting the immune system to treat hypertension: Where are we?, Jennifer L. Gooch and Avadhesh C. Sharma
Targeting the immune system to treat hypertension: Where are we?, Jennifer Gooch and Avadhesh C. Sharma
Gray Zone: Why a Delayed Acceptance of Osteopathic Medicine Persists in the International Community., Rachel L Gougian and Murray R. Berkowitz
To the point: Obstetrics and gynecology global health experiences for medical students, B. S. Hampton, A. W. Chuang, J. F. Abbott, S. D. Beury-Joyner, A. J. Cullimore, J. L. Dalrymple, D. A. Forstein, N. A. Hueppchen, Joseph M. Kaczmarczyk, and S. Page-Ramsey
G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease., Guichun Han and Richard E. White
Keyboard data entry use among osteopathic medical students and residents, Julia M. Helstrom, Erik Langenau, Jeanne M. Sandella, and Beth L. Mote
Hypoxia and free radicals: Role in tumor progression and the use of engineering-based platforms to address these relationships, Abigail Hielscher and S. Gerecht
Detection of Anorexia Nervosa in Primary Care: Effects of Patient Ethnicity, History of Mental Illness, Physician Gender, and Years of Experience., Ashley Higgins, Stacey C. Cahn, Robert A. DiTomasso, and Harry J. Morris
A capstone course with a comprehensive and integrated review of the pharmacy curriculum and student assessment as a preparation for advanced pharmacy practice experiences, Adina C. Hirsch and Harish S. Parihar
Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation., P. E. Hooijman, M. A. Paul, G. J. Stienen, A. Beishuizen, H. W. Van Hees, S. Singhal, M. Bashir, M. T. Budak, Robert J. Barsotti, and et.al
Unaffected Contractility of Diaphragm Muscle Fibers in Humans on Mechanical Ventilation., Pleuni E Hooijman, Marinus A Paul, Ger J M Stienen, Albertus Beishuizen, Hieronymus W H Van Hees, Sunil Singhal, Muhammad Bashir, Murat T. Budak, Jacqueline Morgen, Robert J. Barsotti, Sanford Levine, and Coen A C Ottenheijm
Child involvement, alliance, and therapist flexibility: Process variables in cognitive-behavioural therapy for anxiety disorders in childhood, Jennifer L. Hudson, Philip C. Kendall, Brian C. Chu, Elizabeth A. Gosch, Erin Martin, Alan Taylor, and Ashleigh Knight
miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export, M. B. Hudson, M. E. Woodworth-Hobbs, B. Zheng, J. A. Rahnert, M. A. Blount, Jennifer L. Gooch, C. D. Searles, and S. Russ Price
The Pisiform Growth Plate Is Lost in Humans and Supports a Role for Hox in Growth Plate Formation, Kelsey M Kjosness, Jasmine E Hines, C Owen Lovejoy, and Philip L. Reno
Web-Based Objective Structured Clinical Examination with Remote Standardized Patients and Skype: Resident Experience, Erik E. Langenau, Elizabeth Kachur, and Dot Horber
Introducing Blended Learning to Medical Students in a Clinical Training Environment, Erik Langenau and Douglas Koch
Somatic dysfunction and use of osteopathic manual treatment techniques during ambulatory medical care visits: a CONCORD-PRBN study, John C. Licciardone; Cathleen M. Kearns; Hollis H, King; Michael A. Seffinger; W. Thomas Crow; Peter Zajac; William H. Devine; Reem Y. Abu_Sbaih; Stephen J. Miller; and Murray R. Berkowitz
Chlamydia pneumoniae Infection of Monocytes in vitro Stimulates Innate and Adaptive Immune Responses Relevant to those in Alzheimer's Disease., Charles Lim, Christine Hammond, Susan Hingley, and Brian J. Balin PhD
Detection of Bacterial Antigens and Alzheimer's Disease-like Pathology in the Central Nervous System of BALB/c Mice Following Intranasal Infection with a Laboratory Isolate of Chlamydia pneumoniae, C. Scott Little PhD, Timothy A. Joyce, Christine Hammond, Hazem Matta, David Cahn, Denah Appelt, and Brian J. Balin PhD
Use of a Small Intestine Submucosa Extracellular Matrix Patch in Repeated Carotid Endarterectomy, Nicholas J. Madden, Douglas A. Troutman, and Arthur J. DeMarsico
Pediatric Arytenoid Dislocation: Diagnosis and Treatment., Andrew S. Mallon, Joel E. Portnoy, Tré Landrum, and Robert T. Sataloff
Pediatric Shopping-Cart-Related Injuries Treated in US Emergency Departments, 1990-2011, Keith Martin, Thiphalak Chounthirath, Huiyun Xiang, and Gary A. Smith
Acute and Chronic Compartment Syndromes: Know When to Act Fast, Nancy McLaughlin, Hank Heard, and Steven Kelham
Staff Perspectives on Juvenile Drug Court Operations: A Multi-Site Qualitative Study, A. Mericle, S. Belenko, David Festinger, J. Fairfax-Colombo, and M. McCart
Acute Exposure to High-Fat Diets Increases Hepatic Expression of Genes Related to Cell Repair and Remodeling in Female Rats, Colette N. Miller, Heidi P. Morton, Paula T. Cooney, Tricia G. Winters, Keshia R. Ramseur, Srujana Rayalam, Mary Anne Della-Fera, Clifton A. Baile, and Lynda M. Brown
A Combined Therapeutic Regimen of Buspirone and Environmental Enrichment is more Efficacrious than Either Alone in Enhancing Spatial Learning in Brain-Injured Rats, Christina M. Monaco, Kory M. Gebhardt, Sarah M. Chlebowski, Kaitlyn E. Shaw, and Jeffrey P. Cheng
Chewing Through the Miocene: An Examination of the Feeding Musculature in the Ground Sloth Hapalops from South America (Mammalia: Pilosa), Virginia L Naples and Robert McAfee
Molecular Functions and Significance of the MTA Family in Hormone-Independent Cancer, Zhifeng Ning, Jinfeng Gan, Chaoying Chen, Dianzheng Zhang, and Hao Zhang
Cardiac catheterization: A review for pharmacists, Mebanga Ojong, Chad Weinhold, Afeez Salako, and Jennifer Andres
The Primacy of IQ Subtest Analysis to Understand Reading Performance for Culturally Diverse Groups, Samuel O. Ortiz, Harriet N. Johnson, Gabrielle Wilson, Stella F. Francis, and Yuma Iannotti Tomes
Overview of Adult Outpatient Cancer Pain Management, Sonia Patel
Safe Handling of Chemotherapy for Pharmacists, Sonia Patel
Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Youjuan Pei, Aiming Wang, Yong Zhao, Ling Yan, Min Li, Richard E. White, and Gui Chun Han
Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Y. Pei, A. Wang, Y. Zhao, L. Yan, M. Li, Richard E. White, and G. C. Han
Trajectories of Change in Youth Anxiety During Cognitive-Behavior Therapy., Tara S Peris, Scott N Compton, Philip C Kendall, Boris Birmaher, Joel Sherrill, John March, Elizabeth Gosch, Golda Ginsburg, Moira Rynn, James T McCracken, Courtney P Keeton, Dara Sakolsky, Cynthia Suveg, Sasha Aschenbrand, Daniel Almirall, Satish Iyengar, John T Walkup, Anne Marie Albano, and John Piacentini
Cognitive-Behavioral Therapy for Anxious Youth with a Disability: a Case Study, Jeremy S. Peterman, Alexandra L. Hoff, Elizabeth Gosch, and Philip C. Kendall
Thyroglossal Duct Papillary Carcinoma in a 15-year old Female and Review of Pediatric Cases of thyroglossal duct carcinoma., Michael S Pfeiffer, Grace H Kim, and Miguel Krishnan
24- and 36-Week Outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS), John Piacentini, Shannon Bennett, Scott N. Compton, Phillip C. Kendall, Boris Birmaher, Anne Marie Albano, John March, Joel Sherrill, Dara Sakolsky, Golda Ginsburg, Moira Rynn, R. Lindsey Bergman, Elizabeth Gosch, Bruce Waslick, Satish Iyengar, James McCracken, and John T. Walkup
Efficacy of Super High Dose Proton Pump Inhibitor Administration in Refractory Laryngopharyngeal Reflux: A Pilot Study, Joel E. Portnoy, Naomi D. Gregory, Claudia E. Cerulli, Mary J. Hawkshaw, Deborah Lurie, Philip O. Katz, and Robert T. Sataloff
Inhibition of Long Chain Fatty Ccyl-CoA Synthetase (ACSL) and Ischemia Reperfusion Injury, Allan M. Prior, Man Zhang, Nina Blakeman, Palika Datta, Hung Pham, Qian Chen, Lindon H. Young, Margaret T. Weis, and Duy H. Hua
Bilateral Vocal Fold Immobility, Kelli A. Quercetti and Amanda Hu
Predicting Anxiety Diagnoses and Severity with the CBCL-A: Improvement Relative to Other CBCL Scales?, Kendra L. Read, Cara A. Settipani, Jeremy Peterman, Philip C. Kendall, Scott Compton, John Piacentini, James McCracken, Linsey Bergman, Elizabeth A. Gosch, and et al.
Use of Rapid-Acting Insulin Analogs During Pregnancy, Sara Wilson Reece, Alexander Kanopka, and Iana Mervin
Metformin in gestational diabetes mellitus, Sara Wilson Reece, Harish S. Parihar, and Christina LoBello
Genetic and Developmental Basis for Parallel Evolution and Its Significance for Hominoid Evolution, Philip L. Reno
The Beauty Bias: the Injustice of Appearance in Life and Law, Deborah L. Rhode
Perioperative Nonopioid Agents for Pain Control in Spinal Surgery., Anna Rivkin and Mark Rivkin
Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom
Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom
Thoracolumbar instrumentation with CT-guided navigation (O-arm) in 270 consecutive patients: Accuracy rates and lessons learned, Mark A. Rivkin and Steven S. Yocom
Thoracolumbar instrumentation with CT-guided navigation (O-arm) in 270 consecutive patients: Accuracy rates and lessons learned, Mark A. Rivkin and Steven S. Yocom
Stratigraphy and Vertebrate Paleoecology of Upper Cretaceous? Lowest Paleogene Strata on Vega Island, Antarctica, Eric M. Roberts, Matthew C. Lamanna, Julia A. Clarke, Jin Meng, Eric Gorscak, Joseph J. W. Sertich, Patrick M. O'Connor, Kerin M. Claeson, and Ross D. E. MacPhee
Pubic Bone Osteomyelitis after Salvage High-Intensity Focused Ultrasound for Prostate Cancer, Christopher Robison, R. A. Gor, and M. J. Metro
Impact of celebrity endorsements in disease-specific direct-to-consumer (DTC) advertisements, Brent L. Rollins and Nilesh Bhutada
A Pharmacy Business Management Simulation Exercise as a Practical Application of Business Management Material and Principles, Brent L. Rollins, Rahul Gunturi, and Donald Sullivan
Direct-to-Consumer Advertising of Predictive Genetic Tests: A Health Belief Model Based Examination of Consumer Response., Brent L. Rollins, Shravanan Ramakrishnan, and Matthew Perri
Measuring Community Participation of Adults with Psychiatric Disabilities: Reliability of Two Modes of Data Collection., Mark S. Salzer, Eugene Brusilovskiy, Janet Prvu-Bettger, and Petra Kottsieper
Patterns of Misrepresentation of Clinical Findings on Patient Notes during the COMLEX-USA Level 2-PE, Jeanne M. Sandella, Larissa A. Smith, Laurie A. Gallagher, and Erik E. Langenau
Use of Therapeutic Hypothermia in Cocaine-Induced Cardiac Arrest: Further Evidence, Dane Scantling, Emily Klonoski, and Dominic J. Valentino
Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK-LGL leukaemia, Xiaoshen Sun, Zainul S. Hasanali, Allshine Chen, Dianzheng Zhang, Zin Liu, Hong Gang Wang, David J. Feith, Thomas P. Loughran Jr., and Kailin Xu
Vorapaxar: A Novel Antiplatelet Agent, Stephen Thompson, Carly Duncan, and Jennifer Andres
Cytoprotection of human endothelial cells against oxidative stress by 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im): Application of systems biology to understand the mechanism of action, Xinyu Wang, James A. Bynum, Solomon Stavchansky, and Phillip D. Bowman
Androgen therapy in women, Julie M. Wickman, Ashley Groves, Lauren Wiggins, and Nishman Patel
EgoNet: Identification of human disease ego-network modules, Rendong Yang, Yun Bai, Zhaohui Qin, and Tianwei Yu
A Research Primer, Part 2: Guidelines for Developing a Research Project, David P. Yens, Grace D. Brannan, and Jane Z. Dumsha
Steroid Receptor Coactivator-3 Regulates Glucose Metabolism in Bladder Cancer Cells through Coactivation of Hypoxia Inducible Factor 1α, Wei Zhao, Cunjie Chang, Yangyan Cui, Xiaozhi Zhao, Jun Yang, Lan Shen, Ji Zhou, Zhibo Hou, Zhen Zhang, Changxiao Ye, Donald Hasenmayer, Robert Perkins, Xiaojing Huang, Xin Yao, Like Yu, Ruimin Huang, Dianzheng Zhang, Hongqian Guo, and Jun Yan
Alternative splicing in the variable domain of CaMKIIβ affects the level of F-actin association in developing neurons., Jun Zheng, Lori R. Hardy, Chengshi Xu, Jing Kuang, and Weijing Liao
Submissions from 2013
Biomaterials, Christopher S. Adams
Gallbladder disease: Pathophysiology, diagnosis, and treatment, S. Afamefuna and Shari N. Allen
Treatment of depression in patients on anticoagulation therapy: Antidepressant-warfarin drug interactions, Shari N. Allen, Samuel John, Jennifer Shannon, and Jenna Ferrara
Movie Review: My left foot, Shari N. Allen and Mebanga Ojong
Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer, A. J. Armstrong, M. Haggman, W. M. Stadler, J. R. Gingrich, V. Assikiss, J. Polikoff, J. E. Damber, Laurence Belkoff, A. Nordle, and G. Forsberg
Basis for resveratrol's potential prevention and treatment of obesity osteoporosis, Clifton A. Baile, Mary Anne Della-Fera, and Srujana Rayalam
Analysis of autophagy and inflammasome regulation in neuronal cells and monocytes infected with Chlamydia pneumoniae: Implications for Alzheimer’s disease, Brian J. Balin, Christine J. Hammond, Juliana Zoga, Ahmad B. Cader, Annette K. Slutter, Jonathan M. Anzman, Ian Kohler, Susan T. Hingley, and Denah M. Appelt
Combination Pharmacotherapy in the Treatment of Pulmonary Arterial Hypertension, Kimberly L. Barefield and Gregory V. Stajich
A Comparative Study of Cervical Hysteresis Characteristics after Various Osteopathic Manipulative Treatment (OMT) Modalities, Precious Barnes, Francisco Laboy, Lauren Noto-Bell, Veronica Ferencz MBA, Jeffrey A. Nelson, and Michael L. Kuchera
An open-label, long-term evaluation of the safety, efficacy and tolerability of avanafil in male patients with mild to severe erectile dysfunction, Laurence Belkoff, A. McCullough, I. Goldstein, L. Jones, C. H. Bowden, K. Didonato, B. Trask, and W. W. Day
Assessing impact of not attending lectures on osteopathic medical student performance: Brief survey of the literature and proposed future research, Murray R. Berkowitz
High-Level Specification of a Proposed Information Architecture for Support of a Bioterrorism Early-Warning System, Murray R. Berkowitz
New graduate medical education opportunities found - and lost, Murray R. Berkowitz
Public Health Considerations of Launching Nuclear Waste to the Sun, Murray R. Berkowitz
Regulation of liver growth by glypican 3, CD81, hedgehog, and hhex, Vishakha Bhave, Wendy Mars, Shashikiran Donthamsetty, Xiyue Zhang, Langzhu Tan, Jianhua Luo, William C. Bowen, and George K. Michalopoulos
The Digitization of Historical Artifacts in a Hospital Library, Skye Bickett
What Factors Contribute to or Inhibit Publishing Among Medical Librarians, Skye Bickett, Christine Willis, and Melissa Wright
Expression of membrane anchored cytokines and B7-1 alters tumor microenvironment and induces protective antitumor immunity in a murine breast cancer model, Erica N. Bozeman, Ashley Cimino-Mathews, Deepa K. Machiah, Jaina M. Patel, Arun Krishnamoorthy, Linda Tien, Rangaiah Shashidharamurthya, and Periasamy Selvaraj
A research primer: Basic guidelines for the novice researcher, Grace D. Brannan, Jane Z. Dumsha, and David P. Yens
Defining Treatment Response and Remission in Child Anxiety: Signal Detection Analysis Using the Pediatric Anxiety Rating Scale, Nicole E. Caporino, Douglas M. Brodman, Philip C. Kendall, Anne Marie Albano, Joel Sherrill, John Piacentini, Dara Sakolsky, Boris Birmaher, Scott N. Compton, Golda Ginsburg, Moira Rynn, James McCracken, Elizabeth A. Gosch, Courtney Pierce Keeton, John March, and John T. Walkup
Chlamydia pneumoniae infection of neuronal cells induces changes in calcium-associated gene expression consistent with Alzheimer’s disease, Christopher Andrew Cappellini, Ahmad B. Cader, Keith G. Williams, Juliana Zoga, and Susan T. Hingley
Office-Based Pulsed-Dye Laser Surgery for Laryngeal Lesions: A Retrospective Review, Aaron Centric, Amanda Hu, Yolanda D. Heman-Ackah, Venu Divi, and Robert T. Sataloff
IL-4 Inhibition of IL-1 Induced Matrix Metalloproteinase-3 (MMP-3) Expression in Human Fibroblasts Involves Decreased AP-1 Activation Via Negative Crosstalk Involving of Jun N-Terminal Kinase (JNK), Mariah Chambers, Garrett Kirkpatrick, Michel Evans, Grzegorz Gorski, Sara Foster, and Ruth C. Borghaei
A Review of Tuberculosis: Focus on Bedaquiline, Bonnie Chan, Tina M. Khadem, and Jack Brown
Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state, Chia-ho Cheng, John Leferovich, Xiangming Zhang, Khamilia Bedelbaeva, Dmitri Gourevitch, Cathy J. Hatcher, Craig T. Basson, Ellen Heber-Katz, and Kenneth A. Marx
Comparison of smallpox vs. HIV/AIDS eradication strategies, Annie Chung and Murray R. Berkowitz
Tingitanius tenuimandibulus, a new platyrhinid batoid from the Turonian (Cretaceous) of Morocco and the cretaceous radiation of the Platyrhinidae, Kerin M. Claeson, Charlie J. Underwood, and David J. Ward
The Therapeutic Relationship in Cognitive-Behavioral Therapy and Pharmacotherapy for Anxious Youth, Colleen M. Cummings, Nicole E. Caporino, Cara A. Settipani, Kendra L. Read, Scott N. Compton, John March, Joel Sherrill, John Piacentini, James McCracken, John T. Walkup, Golda Ginsburg, Anne Marie Albano, Moira Rynn, Boris Birmaher, Dara Sakolsky, Elizabeth A. Gosch, Courtney Pierce Keeton, and Philip C. Kendall
Specialty competencies in clinical psychology, Robert A. DiTomasso, Stacey C. Cahn, Susan Panichelli Mindel, and Roger K. McFillin
Primary care psychology, Robert A. DiTomasso, Barbara A. Golden, Stacey C. Cahn, and Amelia G. Gradwell
Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis, Shashikiran Donthamsetty, Vishakha Bhave, Wendy M. Mars, William C. Bowen, Anne Orr, Meagan M. Haynes, Chuanyue Wu, and George K. Michalopoulos
Moving beyond BAC in DUI: Identifying who is at risk of recidivating Dugosh, Festinger, and Marlowe DUI recidivism, K. Dugosh, David Festinger, and D. Marlowe
Overview of: "Moving beyond BAC in DUI: Identifying who is at risk of recidivating", K. Dugosh, David Festinger, and D. Marlowe