The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.

The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.

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Submissions from 2015

Mdivi-1, a Novel Mitochondrial Fission Inhibitor, Exerts Cardioprotective Effects in Myocardial Ischemia/Reperfusion (MI/R) Injury, Devon Stutzman, Carly Schmidgall, Israel Benjamin, Qian Chen, Cathy J. Hatcher, Robert Barsotti, and Lindon Young

Lung cancer overview: Focus on newer therapies, Sonia Amin Thomas

New and emerging therapies for Melanoma, Sonia Amin Thomas, A. G. Douglas, A. Rose, E. Dingsangha, and Valerie Tapia

Metformin represses androgen-dependent and androgen-independent prostate cancers by targeting androgen receptor, Yan Wang, Gaolei Lie, Dali Tong, Henna Parmar, Donald Hasenmayer, Wenqiang Yuan, Dianzheng Zhang, and Jun Jiang

The Risk of Risk Assessment: Pressure Ulcer Assessment and the Braden Sca;e, Ilene Warner-Maron

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A Novel Segmentation Approach For Brain Tumor in MRI, Yong Wei and Hugh Keith Brown

Forearm Fractures, Johnathan J. Whitaker, Brandon M. Tauberg, Michael S. Kwon, and Martin J. Herbert

Antibody Effector Functions Mediated by FcY-Receptors Are Compromised during Persistent Viral Infection, Andreas Wieland, Rangaiah Shashidharamurthy, Alice Kamphorst, Jinhwan Han, Rachael Aubert, Biswa Choudhury, Sean Stowell, Junghwa Lee, George Punkosdy, and et al.

The cost-effectivness of OM-86 in managing respiratory tract infections in China, Jianwei Xuan, Lijie Wang, Hongjun Yin, Dennis Xuan, Yan Zhou, and Shanlian Hu

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Effects of a particular heptapeptide on the IFN-α-sensitive CML cells, Fulan Yang, Fangzhi Chen, Xinxing Wan, Xi Zhou, Meijuan Zhou, Hanchun Chen, Junjiang Fu, and Dianzheng Zhang

Selective estrogen receptor alpha agonist GTx-758 decreases testosterone with reduced side effects of androgen deprivation therapy in men with advanced prostate cancer, Evan Y. Yu, Robert H. Getzenburg, Christopher C. Coss, Mark M. Gittelman, Thomas Keane, Ronald Tutrone, Laurence Belkoff, Robert Given, Joel Bass, and et al.

Submissions from 2014

Climatic Severity Victims of Upstream Water Piracy Strongly Evidencing Inland Water Depletion-Caused Global Warming vis-a-vis Cooling, M. M. Adel, Mahmood R. Hossain, and Saiyeeda F. Hossain

Pharmacist-Initiated Prior Authorization Process to Improve Patient Care in a Psychiatric Acute Care Hospital, Shari N. Allen and Mebanga Ojong-Salako

A Practical Guide to Concentrated Insulin for Pharmacists, Jennifer Andres and Jennifer N. Clements

A Possible Case of Gabapentin-Induced Mild Hyperglycemia, Jennifer Andres, Jennifer N. Clements, and Donna Salmiery

Postoperative cognitive dysfunction, Alzheimer's disease, and anesthesia, S. S. Arora, Jennifer L. Gooch, and P. S. Garcia

Transdermal Delivery of Proteins Using a Combination of Iontophoresis and Microporation, Yun Bai, Vishal Sachdeva, Hyun Kim, Phillip M. Friden, and Ajay K. Banga

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Genome-wide sequencing of small RNAs reveals a tissue-specific loss of conserved microRNA families in Echinococcus granulosus, Yun Bai, Zhuangzhi Zhang, Lei Jin, Hui Kang, Yongquiang Zhu, Lu Zhang, Xia Li, Fengshou Ma, Li Zhao, and et al.

Etiology and Pathogenesis of Late-Onset Alzheimer's Disease, Brian J. Balin PhD and Alan P. Hudson

More on Nicotine Poisoning in Infants, Robert A. Bassett and Kevin Osterhoudt

Nicotine Poisoning in an Infant, Robert A. Bassett, Kevin Osterhoudt, and Tecla Brabazon

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Rethinking the Core List of Journals for Libraries that Serve Schools and Colleges of Pharmacy., Robert D Beckett, Sabrina W. Cole, Hannah K Rogers, Skye Bickett, Christina Seeger, and Jennifer A McDaniel

Prize-based contingency management for the treatment of substance abusers: a meta-analysis, L. Benishek, K. Dugosh, K. Kirby, J. Matejkowski, N. Clements, B. Seymour, and David Festinger

Application of osteopathy in the cranial field to treat left superior homonymous hemianopsia, Murray R. Berkowitz

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BrowZine: A Review, Skye Bickett

Comparison of Indocyanine Green Fluorescent Angiography to Digital Subtraction Angiography in Brain Arteriovenous Malformation Surgery, Christopher J. Bilbao, Tarun Bhalla, Shamsher Dalal, Hiren Patel, and Amir R. Dehdashti

Respiratory syncytial virus: Diagnosis, prevention, and management of complications, Marie Katie Bozman, Carmen Echols, and Jennifer Andres

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Meglumine Exerts Protective Effects Against Features of Metabolic Syndrome and Type II Diabetes, Arturo Bravo Nuevo, Alice Marcy, Minzhou Huang, Frank Kappler, Jennifer Mulgrew, Lisa Laury-Kleintop, Melvin Reichman, Annette Tobia, and George C Prendergast

Evidence of Declining Empathy in Third Year Osteopathic Medical Students, Hilary M. Caruso and Bettina Bernstein

Marked improvement of vulvovaginitis of unknown origin in a pediatric patient - Case report, Jerome H. Check and Rachael A. Cohen

Severe Headaches from Intracranial Hypertension (Pseudotumor Cerebri) Abrogated by Treatment with Dextroamphetamine Sulfate, Jerome H. Check and Rachael A. Cohen

Sympathomimetic Amine Therapy Found Effective for Treatment of Refractory Chronic Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy), Jerome H. Check and Rachael A. Cohen

The Triad of Luteal Phase Ocular Migraines, Interstitial Cystitis, and Dyspareunia as a Result of Sympathetic Nervous System Hypofunction, Jerome H. Check and Rachael A. Cohen

Failure to Improve a Thin Endometrium in the Late Proliferative Phase with Uterine Infusion of Granulocyte-Colony Stimulating Factor, Jerome H. Check, Rachael A. Cohen, and J. K. Choe

Methamphetamine abuse usurps hippocampal neural network operations undergirding memory consolidation, Sanika Chirwa, Adwoa Aduonum, and Habibeh Khoshbouei

The Impacts of Comparative Anatomy of Electric Rays (Batoidea: Torpediniformes) on their Systematic Hypotheses, Kerin M. Claeson

A Revision of the Upper Cretaceous Lepidosirenid Lungfishes from the Quseir Formation, Western Desert, Central Egypt, Kerin M. Claeson, Hesham M. Sallam, Patrick M. O'Connor, and Joseph J. W. Sertich

Response to letter to the editor: A practical guide to concentrated insulin for pharmacists, Jennifer Clements and Jennifer Andres

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Predictors and moderators of treatment response in childhood anxiety disorders: Results from the CAMS trial, Scott N. Compton, Tara S. Peris, Daniel Almirall, Boris Birmaher, Joel Sherrill, Phillip C. Kendall, John S. March, Elizabeth A. Gosch, Golda S. Ginsburg, and et al.

Somatic Complaints in Anxious Youth, Sarah A. Crawley, Nicole E. Caporino, Boris Birmaher, Golda Ginsburg, John Piacentini, Anne Marie Albano, Joel Sherrill, Dara Sakolsky, Scott N. Compton, Moira Rynn, James McCracken, Elizabeth Gosch, Courtney Pierce Keeton, John March, John T. Walkup, and Philip C. Kendall

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Phenotype of Transgenic Mice Carrying a Very Low Copy Number of the Mutant Human G93A Superoxide Dismutase-1 Gene Associated with Amyotrophic Lateral Sclerosis, Jeffrey S. Deitch, Guillermo M. Alexander, Andrew Bensinger, Steven Yang, Juliann T. Jiang, and Terry D. Heiman-Patterson

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Tbx5 is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis., Nata Y Diman, Gabriel Brooks, Boudewijn P Kruithof, Olivier Elemento, Jonathan G Seidman, Christine Seidman, Craig T Basson, and Cathy J. Hatcher

Incorporation of pazopanib in maintenance therapy of ovarian cancer, A. DuBois, A. Floquet, J. Kim, J. Rau, J. Del Campo, M. Friedlander, S. Pignata, K. Fujiwara, Rocco J. Crescenzo, and et al.

The Survey of Treatment Entry Pressures (STEP): identifying client's reasons for entering substance abuse treatment, K. Dugosh, David Festinger, K. Lynch, and D. Marlowe

Developing an index to measure the voluntariness of consent to research, K. Dugosh, David Festinger, D. Marlowe, and N. Clements

Contingency management for cocaine treatment: Cash vs. vouchers, David Festinger, K. Dugosh, K. Kirby, and B. Seymour

Achieving new levels of recall in consent to research by combining remedial and motivational techniques, David Festinger, K. Dugosh, D. Marlowe, and N. Clements

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Malnutrition and Depression, Katherine E. Galluzzi, Barry Rovner, and Stephen Di Sabatino

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Myo/Nog Cells: Targets for Preventing the Accumulation of Skeletal Muscle-Like Cells in the Human Lens, Jacquelyn Gerhart, M. Greenbaum, V. Scheinfeld, P. Fitzgerald, M. Crawford, Arturo Bravo Nuevo, M. Pitts, and Mindy George-Weinstein

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Immediate Return to Ambulation and Improved Functional Capacity for Rehabilition in Complex Regional Pain Syndrome following Early Implantation of a Spinal Cord Stimulation System, Brandon Jesse Goff, Jeremy Wingseng Naber, John Patrick McCallin, Edward Michael Lopez, Kevin Brant Guthmiller, Karl Alan Lautenschlager, Tristan Toll Lai, Dean Harry Hommer, and Gonzalez Raul Marin

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Targeting the immune system to treat hypertension: Where are we?, Jennifer L. Gooch and Avadhesh C. Sharma

Targeting the immune system to treat hypertension: Where are we?, Jennifer Gooch and Avadhesh C. Sharma

Gray Zone: Why a Delayed Acceptance of Osteopathic Medicine Persists in the International Community., Rachel L Gougian and Murray R. Berkowitz

To the point: Obstetrics and gynecology global health experiences for medical students, B. S. Hampton, A. W. Chuang, J. F. Abbott, S. D. Beury-Joyner, A. J. Cullimore, J. L. Dalrymple, D. A. Forstein, N. A. Hueppchen, Joseph M. Kaczmarczyk, and S. Page-Ramsey

G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease., Guichun Han and Richard E. White

Keyboard data entry use among osteopathic medical students and residents, Julia M. Helstrom, Erik Langenau, Jeanne M. Sandella, and Beth L. Mote

Hypoxia and free radicals: Role in tumor progression and the use of engineering-based platforms to address these relationships, Abigail Hielscher and S. Gerecht

Detection of Anorexia Nervosa in Primary Care: Effects of Patient Ethnicity, History of Mental Illness, Physician Gender, and Years of Experience., Ashley Higgins, Stacey C. Cahn, Robert A. DiTomasso, and Harry J. Morris

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A capstone course with a comprehensive and integrated review of the pharmacy curriculum and student assessment as a preparation for advanced pharmacy practice experiences, Adina C. Hirsch and Harish S. Parihar

Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation., P. E. Hooijman, M. A. Paul, G. J. Stienen, A. Beishuizen, H. W. Van Hees, S. Singhal, M. Bashir, M. T. Budak, Robert J. Barsotti, and et.al

Unaffected Contractility of Diaphragm Muscle Fibers in Humans on Mechanical Ventilation., Pleuni E Hooijman, Marinus A Paul, Ger J M Stienen, Albertus Beishuizen, Hieronymus W H Van Hees, Sunil Singhal, Muhammad Bashir, Murat T. Budak, Jacqueline Morgen, Robert J. Barsotti, Sanford Levine, and Coen A C Ottenheijm

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Child involvement, alliance, and therapist flexibility: Process variables in cognitive-behavioural therapy for anxiety disorders in childhood, Jennifer L. Hudson, Philip C. Kendall, Brian C. Chu, Elizabeth A. Gosch, Erin Martin, Alan Taylor, and Ashleigh Knight

miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export, M. B. Hudson, M. E. Woodworth-Hobbs, B. Zheng, J. A. Rahnert, M. A. Blount, Jennifer L. Gooch, C. D. Searles, and S. Russ Price

The Pisiform Growth Plate Is Lost in Humans and Supports a Role for Hox in Growth Plate Formation, Kelsey M Kjosness, Jasmine E Hines, C Owen Lovejoy, and Philip L. Reno

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Web-Based Objective Structured Clinical Examination with Remote Standardized Patients and Skype: Resident Experience, Erik E. Langenau, Elizabeth Kachur, and Dot Horber

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Introducing Blended Learning to Medical Students in a Clinical Training Environment, Erik Langenau and Douglas Koch

Somatic dysfunction and use of osteopathic manual treatment techniques during ambulatory medical care visits: a CONCORD-PRBN study, John C. Licciardone; Cathleen M. Kearns; Hollis H, King; Michael A. Seffinger; W. Thomas Crow; Peter Zajac; William H. Devine; Reem Y. Abu_Sbaih; Stephen J. Miller; and Murray R. Berkowitz

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Chlamydia pneumoniae Infection of Monocytes in vitro Stimulates Innate and Adaptive Immune Responses Relevant to those in Alzheimer's Disease., Charles Lim, Christine Hammond, Susan Hingley, and Brian J. Balin PhD

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Detection of Bacterial Antigens and Alzheimer's Disease-like Pathology in the Central Nervous System of BALB/c Mice Following Intranasal Infection with a Laboratory Isolate of Chlamydia pneumoniae, C. Scott Little PhD, Timothy A. Joyce, Christine Hammond, Hazem Matta, David Cahn, Denah Appelt, and Brian J. Balin PhD

Use of a Small Intestine Submucosa Extracellular Matrix Patch in Repeated Carotid Endarterectomy, Nicholas J. Madden, Douglas A. Troutman, and Arthur J. DeMarsico

Pediatric Arytenoid Dislocation: Diagnosis and Treatment., Andrew S. Mallon, Joel E. Portnoy, Tré Landrum, and Robert T. Sataloff

Pediatric Shopping-Cart-Related Injuries Treated in US Emergency Departments, 1990-2011, Keith Martin, Thiphalak Chounthirath, Huiyun Xiang, and Gary A. Smith

Acute and Chronic Compartment Syndromes: Know When to Act Fast, Nancy McLaughlin, Hank Heard, and Steven Kelham

Staff Perspectives on Juvenile Drug Court Operations: A Multi-Site Qualitative Study, A. Mericle, S. Belenko, David Festinger, J. Fairfax-Colombo, and M. McCart

Acute Exposure to High-Fat Diets Increases Hepatic Expression of Genes Related to Cell Repair and Remodeling in Female Rats, Colette N. Miller, Heidi P. Morton, Paula T. Cooney, Tricia G. Winters, Keshia R. Ramseur, Srujana Rayalam, Mary Anne Della-Fera, Clifton A. Baile, and Lynda M. Brown

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A Combined Therapeutic Regimen of Buspirone and Environmental Enrichment is more Efficacrious than Either Alone in Enhancing Spatial Learning in Brain-Injured Rats, Christina M. Monaco, Kory M. Gebhardt, Sarah M. Chlebowski, Kaitlyn E. Shaw, and Jeffrey P. Cheng

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Chewing Through the Miocene: An Examination of the Feeding Musculature in the Ground Sloth Hapalops from South America (Mammalia: Pilosa), Virginia L Naples and Robert McAfee

Molecular Functions and Significance of the MTA Family in Hormone-Independent Cancer, Zhifeng Ning, Jinfeng Gan, Chaoying Chen, Dianzheng Zhang, and Hao Zhang

Cardiac catheterization: A review for pharmacists, Mebanga Ojong, Chad Weinhold, Afeez Salako, and Jennifer Andres

The Primacy of IQ Subtest Analysis to Understand Reading Performance for Culturally Diverse Groups, Samuel O. Ortiz, Harriet N. Johnson, Gabrielle Wilson, Stella F. Francis, and Yuma Iannotti Tomes

Overview of Adult Outpatient Cancer Pain Management, Sonia Patel

Safe Handling of Chemotherapy for Pharmacists, Sonia Patel

Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Youjuan Pei, Aiming Wang, Yong Zhao, Ling Yan, Min Li, Richard E. White, and Gui Chun Han

Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Y. Pei, A. Wang, Y. Zhao, L. Yan, M. Li, Richard E. White, and G. C. Han

Trajectories of Change in Youth Anxiety During Cognitive-Behavior Therapy., Tara S Peris, Scott N Compton, Philip C Kendall, Boris Birmaher, Joel Sherrill, John March, Elizabeth Gosch, Golda Ginsburg, Moira Rynn, James T McCracken, Courtney P Keeton, Dara Sakolsky, Cynthia Suveg, Sasha Aschenbrand, Daniel Almirall, Satish Iyengar, John T Walkup, Anne Marie Albano, and John Piacentini

Cognitive-Behavioral Therapy for Anxious Youth with a Disability: a Case Study, Jeremy S. Peterman, Alexandra L. Hoff, Elizabeth Gosch, and Philip C. Kendall

Thyroglossal Duct Papillary Carcinoma in a 15-year old Female and Review of Pediatric Cases of thyroglossal duct carcinoma., Michael S Pfeiffer, Grace H Kim, and Miguel Krishnan

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24- and 36-Week Outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS), John Piacentini, Shannon Bennett, Scott N. Compton, Phillip C. Kendall, Boris Birmaher, Anne Marie Albano, John March, Joel Sherrill, Dara Sakolsky, Golda Ginsburg, Moira Rynn, R. Lindsey Bergman, Elizabeth Gosch, Bruce Waslick, Satish Iyengar, James McCracken, and John T. Walkup

Efficacy of Super High Dose Proton Pump Inhibitor Administration in Refractory Laryngopharyngeal Reflux: A Pilot Study, Joel E. Portnoy, Naomi D. Gregory, Claudia E. Cerulli, Mary J. Hawkshaw, Deborah Lurie, Philip O. Katz, and Robert T. Sataloff

Inhibition of Long Chain Fatty Ccyl-CoA Synthetase (ACSL) and Ischemia Reperfusion Injury, Allan M. Prior, Man Zhang, Nina Blakeman, Palika Datta, Hung Pham, Qian Chen, Lindon H. Young, Margaret T. Weis, and Duy H. Hua

Bilateral Vocal Fold Immobility, Kelli A. Quercetti and Amanda Hu

Predicting Anxiety Diagnoses and Severity with the CBCL-A: Improvement Relative to Other CBCL Scales?, Kendra L. Read, Cara A. Settipani, Jeremy Peterman, Philip C. Kendall, Scott Compton, John Piacentini, James McCracken, Linsey Bergman, Elizabeth A. Gosch, and et al.

Use of Rapid-Acting Insulin Analogs During Pregnancy, Sara Wilson Reece, Alexander Kanopka, and Iana Mervin

Metformin in gestational diabetes mellitus, Sara Wilson Reece, Harish S. Parihar, and Christina LoBello

Genetic and Developmental Basis for Parallel Evolution and Its Significance for Hominoid Evolution, Philip L. Reno

The Beauty Bias: the Injustice of Appearance in Life and Law, Deborah L. Rhode

Perioperative Nonopioid Agents for Pain Control in Spinal Surgery., Anna Rivkin and Mark Rivkin

Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom

Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom

Thoracolumbar instrumentation with CT-guided navigation (O-arm) in 270 consecutive patients: Accuracy rates and lessons learned, Mark A. Rivkin and Steven S. Yocom