The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.

The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.


Submissions from 1987

Correlation of palpatory observations with the anatomic locus of acute myocardial infarction, H. O. Rosero, Charlotte H. Greene, and Domemic A. DiBias

Submissions from 1986

Enhancing effectiveness of paradoxical intention in treating travel restriction in agoraphobia, L. Michael Ascher, D. E. Schotte, and J. B. Grayson

Avenues for Entry of Peripherally Administered Protein to the Central Nervous System in Mouse, Rat, and Squirrel Monkey, Brian J. Balin, Richard D. Broadwell, Michael Salcman, and Magdy El-Kalliny

Calcium regulation in vascular smooth muscle: Is there a pattern to its variability within the arterial tree?, J. A. Bevan, R. D. Bevan, J. J. Hwa, Mary P. Owen, and F. M. Tayo

Phospholipase C Activity in Palate Mesenchyme Cells: Calcium and pH Requirements, Substrate Specificity, and Subcellular Localization, K P Chepenik, Mindy George-Weinstein, and R Caamano-Haigh

Cystoscopic laser surgery: An animal model, Leonard H. Finkelstein, Domenic A. DeBias, and Charlotte H. Greene

Isolation of cilia from porcine tracheal epithelium and extraction of dynein arms, Annette T. Hastie, David T. Dicker, Susan T. Hingley, Friedrich Kueppers, Michael L. Higgins, and George Weinbaurn

Rhamnolipid from Pseudomonas aeruginosa inactivates mammalian tracheal ciliary axonemes., Annette T. Hastie, Susan T. Hingley, M. L. Higgins, Friedrich Kueppers, and T. Shryock

Use of selective vs standard sheep blood agar for the diagnosis of hemolytic streptococcus group A pharyngitis, J. L. Haym, Robert A. DiTomasso, and S. Colameco

Disruption of respiratory cilia by proteases including those of Pseudomonas aeruginosa, Susan T. Hingley, A. T. Hastie, Friedrich Kueppers, and M. L. Higgins

Effect of ciliostatic factors and Pseudomonas aeruginosa on rabbit respiratory cilia, Susan T. Hingley, A. T. Hastie, Friedrich Kueppers, M. L. Higgins, G. Weinbaum, and T. Shryock

Efficacy of the neodymium:YAG laser in vasovasostomy: A preliminary communication, Perry Weiner, Leonard Finkelstein, Charlotte H. Greene, and Domenic A. DiBias

Submissions from 1985

Local fibrinolysis for the treatment of massive pulmonary embolism: Efficacy of streptokinase infusion through pulmonary arterial catheter, J. E. Ambrose, Michael A. Venditto, and W. H. Dickerson

Paradoxical Intention, L. Michael Ascher

Paradoxical intention in behavior therapy: A review of the experimental literature, L. Michael Ascher

Empirical issues in paradox, L. Michael Ascher, M. Bowers, and D. E. Schotte

Endocytic and Exocytic Pathways of the Neuronal Secretory Process and Trans-Synaptic Transfer of Wheat Germ Agglutinin-Horseradish Peroxidase in vivo, Richard D. Broadwell and Brian J. Balin

Effects of dexamethasone on phospholipase activities in palate mesenchyme cells in vitro., K P Chepenik, Mindy George-Weinstein, and R M Greene

Posttraumatic syringomyelia, Gerald E. Dworkin and W. E. Staas Jr.

Psychological Functioning After Severe Closed Head Injury, David W. Ellis and Bruce S. Zahn

Electroresection followed by neodymium-YAG laser photocoagulation of the dog prostate for establishment of safety parameters, Leonard H. Finkelstein, Bruce Frantz, Lillian Longendorfer Hynes, Domenic A. DeBias, Charlotte H. Greene, and Frederick Monson

Role of natural killer cells in the mechanism of the antitumor effect of interferon on Moloney sarcoma virus-transformed cells, Kerin L. Fresa and D. M. Murasko

Phospholipase A Activities in Embryonic Palate Mesenchyme Cells in Vitro, Mindy George-Weinstein and K P. Chepenik

Rest-exercise radionuclide angiographic assessment of left ventricular function in chronic aortic regurgitation: Significance of serial studies in medically versus surgically treated groups, F. J. Lumia, R. M. MacMillan, P. A. Germon, Bruce Kornberg, J. Fernandez, and V. Maranhao

Clinical analysis of errors, George McCloskey

Mechanical and biochemical characterization of the contraction elicited by a calcium-independent myosin light chain kinase in chemically skinned smooth muscle, U. Mrwa, K. Güth, J. C. Rüegg, R. J. Paul, S. Boström, Robert Barsotti, and D. Hartshorne

Acetylcholine induced endothelial-dependent vasodilation increases as artery diameter decreases in the rabbit ear, Mary P. Owen and J. A. Bevan

Phentolamine-resistant neurogenic constriction occurs in small arteries at higher frequencies, Mary P. Owen, C. Quinn, and J. A. Bevan

Pharmacological Aspects of Drug Abuse, G. V. Rossi and Frederick J. Goldstein


A Manual for House Staff on Pulmonary Service at PCOM, John P. Simelaro


Blood Gas and Ventilator Manual for House Staff on Pulmonary Service, John P. Simelaro


Pulmonary Function Manual, John P. Simelaro

Submissions from 1984

Further Studies of the Secretory Process in Hypothalamo neurohypophysial Neurons. An Analysis Using Immunochemistry, Wheat Germ Agglutinin-Peroxidase and Native Peroxidase, Richard D. Broadwell, Anne M. Cataldo, and Brian J. Balin

Endoscopic diagnosis and removal of a duodenal wall gastrinoma., William J. Gilhool

Comparison of three cognitive strategies in altering pain behaviors on a cold pressor task., R. M. Gilligan, L. Michael Ascher, J. Wolper, and C. Bochachevsky

Contrasting effects of acute vs. chronic tricyclic antidepressant treatment on central morphine analgesia, D. E. Kellstein, R. T. Malseed, and Frederick J. Goldstein

Paradoxical intention in the treatment of agoraphobia and other anxiety disorders, L. Michelson and L. Michael Ascher

Safety considerations and safety protocol for laser surgery, R. M. Mohr, B C. McDonnell, M. Unger, and Theodore P. Mauer

Primary afferent projections to the sacral secondary visceral gray: A quantitative electron microscopic examination in the cat, Michael Nolan and H. Keith Brown

Feline analgesia following central administration of opioids, M. H. Ossipov, Frederick J. Goldstein, and R. T. Malseed

Effect of α2 adrenergic agents upon central etorphine antinociception in the cat, M. H. Ossipov, R. T. Malseed, L. M. Eisenman, and Frederick J. Goldstein

Elevated theophylline blood levels from institution of nifedipine therapy, S. J. Parillo and Michael A. Venditto

Pyridoxine toxicity: Report of a case, A. Vasile, R. Goldberg, and Bruce Kornberg

The incidence of tricuspid valvular regurgitation in patients with severe chronic obstructive pulmonary disease as determined by two-dimensional echocardiography, Michael Venditto, D. Pisano, John P. Simelaro, and W. Dickerson

Submissions from 1983

The initial assessment and care of the patient with multiple trauma, John W. Becher Jr.

A Blood-Brain Barrier? Yes and No., Richard D. Broadwell, Brian J. Balin, Michael Salcman, and R. S. Kaplan

Myosin light chain phosphorylation does not modulate cross-bridge cycling rate in mouse skeletal muscle, T. M. Butler, M. J. Siegman, S. U. Mooers, and Robert J. Barsotti

Hydrolysis of Phospholipids By Embryonic Palate Mesenchyme Cells, in Vitro., K. P. Chepenik and Mindy George-Weinstein

Factors influencing program selection among family practice residents, Robert A. DiTomasso, J. P. DiLauro, and S. T. Carter Jr.

Proliferation of Cells Undergoing Chondrogenesis in Vitro, Mindy George-Weinstein, K P Chepenik, and M H Schneiderman

Narcotic Analgesics, Frederick J. Goldstein

Protease production by Pseudomonas aeruginosa isolates from patients with cystic fibrosis, Annette T. Hastie, Susan T. Hingley, Friedrich Kueppers, M. L. Higgins, C. S. Tannenbaum, and George Weinbaum

S-T segment variants in young, adult, black women, Bruce Kornberg

When to Refer Your Patient for Heart Valve Replacement, Bruce Kornberg

Manipulating the explicit demand of paradoxical intention instructions, B. D. Ott, B. A. Levine, and L. Michael Ascher

Importance of 'cut-end' effects in in vitro artery segments, Mary P. Owen; D. A. Nay; R, D, Bevan; and J. A. Bevan

Adrenergic control in three artery segments of diminishing diameter in rabbit ear, Mary P. Owen, J. G. Walmsley, and M. F. Mason

Bacampicillin in the treatment of acute sinusitis and bronchopulmonary disease, John P. Simelaro, G. Henwood, and A. DeSalvo

Assessment of social anxiety: a controlled comparison among social phobics, obsessive-compulsives, agoraphobics, sexual disorders and simple phobies, R, M. Turner; D. Meles; and Robert A. DiTomasso

Medial morphometry and mechanics of sequential rabbit ear arteries and myograph ring segments., J. G. Walmsley, Mary P. Owen, and J. A. Bevan

Submissions from 1982

Flight 30 ... over the end!, John M. Cavenagh

Arachnoid cyst associated with psychological disturbance., S. Colameco and Robert A. DiTomasso

Patient self-monitoring of behavior., Robert A. DiTomasso and S. Colameco

Elevation in analgetic effect and plasma levels of morphine by desipramine in rats, Frederick J. Goldstein, P. Mojaverian, M. Ossipov, and B. N. Swanson

Comments on Super's observations, Edwin L. Herr, Roland H. Good, George McCloskey, and Anna D. Weitz

Secondary school curriculum and career behavior in young adults, Edwin L. Herr, Roland H. Good, George McCloskey, and Anna D. Weitz

The Hydra Attenuata System for Detection of Teratogenic Hazards, E. Marshall Johnson, Regina M. Gorman, Bradley E.G Gabel, and Mindy George-Weinstein

Increased plasma levels and analgesic effect of morphine following desipramine pretreatment in rats, P. Mojaverian, Frederick J. Goldstein, M. H. Ossipov, and B. N. Swanson

Modulation of central etorphine analgesia by alpha-2 agonists in the cat, M. H. Ossipov, Frederick J. Goldstein, and R. T. Malseed

Augmentation of central and peripheral morphine analgesia by desipramine, M. H. Ossipov, R. T. Malseed, and Frederick J. Goldstein

Differential effects of LSD serotonin and l-tryptophan on visually evoked responses, J. R. Strahlendorf, Frederick J. Goldstein, G. V. Rossi, and R. T. Malseed

Therapist factor in the treatment of insomnia, R. M. Turner and L. Michael Ascher

Submissions from 1981

Employing paradoxical intention in the treatment of agoraphobia, L. Michael Ascher

An ultrastructural examination of dorsal root input to the sacral secondary visceral gray, Michael Nolan and H. Keith Brown

Selective neurotoxic action of capsaicin on glomerular C-type terminals in rat substantia gelatinosa, N. Palermo and H. Keith Brown

Isoniazid-induced serum sickness: Report of case, John P. Simelaro, J. Dale, and D. Guest

Pleural aspergillosis treated with intrapleural amphotericin B: report of case, John P. Simelaro, M. Ghen, and P. Ginsberg

Submissions from 1980

Characteristics of doctoral and nondoctoral school psychology programs: Their implications for the entry-level doctorate, J. L. French and George McCloskey

Case reports. Cavitary Hodgkin's disease., R. F. Johnson and John P. Simelaro

Calcium dependence of norepinephrine-induced vascular contraction in experimental diabetes, Mary P. Owen and G. O. Carrier

Evaluation of doxycycline in the treatment of acute sinusitis and bronchopulmonary disease, John P. Simelaro, M. Ghen, and P. Ginsberg

Intermittent mandatory ventilation and continuous positive airway pressure: Two inexpensive methods of delivery, John P. Simelaro, R. Greenberg, and J. Cannavo

Effect of erythrocytes of androgens on 2,3-diphosphoglycerate in patients with chronic obstructive pulmonary disease, John P. Simelaro, Michael Venditto, and M. Ghens

Psychometric analysis of the Willoughby Personality Schedule, R. M. Turner and Robert A. DiTomasso

The behavioral treatment of insomnia. A review and methodological analysis of the evidence, R. M. Turner and Robert A. DiTomasso

Submissions from 1979

Paradoxical intention in the treatment of urinary retention, L. Michael Ascher

Paradoxical intention and insomnia: an experimental investigation, L. Michael Ascher and R. M. Turner

Ultrastructure and quantitative synaptology of the sacral parasympathetic nucleus, H. Keith Brown

Diabetes mellitus in pregnancy, surgery, and infection, W. M. Comiskey, Pat A. Lannutti, and M. L. Rosner

Characteristics of school psychology program directors and program production, J. L. French and George McCloskey

Evaluation of narcotic analgetic activity using a cat tail-flick procedure, Frederick J. Goldstein and R. T. Malseed

Enhancement of morphine analgesia by tricyclic antidepressants, R. T. Malseed and Frederick J. Goldstein

Dysfunction of the Innominate Complex, Alexander S. Nicholas

The use of HLA-B27 in rheumatic diseases., Richard A. Pascucci and N. A. Cummings

A within-subject analysis of stimulus control therapy with severe sleep-onset insomnia, R. M. Turner and L. Michael Ascher

Controlled comparison of progressive relaxation, stimulus control, and paradoxical intention therapies for insomnia, R. M. Turner and L. Michael Ascher

Submissions from 1978

Use of paradoxical intention in a behavioral program for sleep onset insomnia, L. Michael Ascher and J. S. Efran

Detection of narcotic analgesic activity utilizing a cat tail flick procedure, Frederick J. Goldstein and R. T. Malseed

Palpation in Osteopathic Medicine, Alexander S. Nicholas

Submissions from 1977

The role of hypnosis in behavior therapy, L. Michael Ascher