Theses/Dissertations from 2023

Evaluation of the olfactory neuro-epithelium and limbic system from cadaveric Alzheimer’s disease and non-Alzheimer’s disease brains for evidence of pathology and Chlamydia pneumoniae infection, Matthew Connolly

Examining the Effects of Reelin on Vascular Endothelial Cell Polarity, Heidi Chrystle Elnathan

Amelioration of Retinal Degeneration in C3H/HeJ Mice by Intravitreal Injection of Noggin, Carlos Font

Localization of Ruthenium Substituted Protein in HT-1080 Human Fibrosarcoma Cells, Alisa F. Hicks

Anti-myeloma Effects of Conjugated Arginyl-Glycyl-Aspartic Acid Ultrafine Iron Oxide Nanoparticles Loaded with Xanthohumol, Shamaza Rivers-Johnson

Examining MMP-9 following early-life seizures in larval zebrafish, Christopher Stegmuller


RhoB is a Key Regulator of Neuronal Cell Death in the Stressed Retina, E-Jine Tsai

Theses/Dissertations from 2022

Assessing Seizure Susceptibility Following Early-Life Seizures in Zebrafish, Kasulul Melissa Bhuiyan


Associating infection by Chlamydia pneumoniae and the presence of amyloid-β plaques in the brains of Alzheimer’s disease/dementia patients, Paul J. G. Carango

The Use of Ruthenium Substituted NGR-Tagged Rubredoxin for Targeted Cancer Therapeutic Drug Delivery, Alexa T. Cornwell


Potential Differences in Male versus Female Lymph Nodes, Vikas Damineni

Examination of the Potential for ZO1 and ZEB2 to Mediate the Effects of AJAP1 in Epithelial Cells During Cardiovascular Development, Alexander Gerick

Inhibitory effect of phytochemicals on SARS-CoV-2 PLpro proteolytic and deubiquitinase activity, Anasha Kawall

The Relationship of ADAMTS1 and ANGPT2 with Reelin in Vascular Endothelial Cells, Beryl Khakina


Synthesis and Characterization of Novel Reformulated Bioactive Paclitaxel Complexes and Considerations for Administration Via Inhalation Method for Targeted Lung Cancer Treatment, Teighlor Nicole Livingston

Investigation of the role of PARP-1 and CD38 in modulating NAD+ levels in spinal and bulbar muscular atrophy, Caroline E. Lozzi


Mechanisms involved in mitoquinone-mediated protection of H9C2 cells against anti-cancer drug doxorubicin-induced cardiotoxicity, Kelly Annie Mercado


The Role of BKCa Channel Expression and Functional Regulation on the Development of Pulmonary Hypertension in Type 2 Diabetic Individuals, Tahirah Nimi

Phytochemicals as Potential Agents Against 3-Chymotrypsin Like Protease (3CLPro) in SARS-CoV-2, Avini Sharma

Cytotoxicity, Synergism and Apoptosis Induction: Effects of Resveratrol Derivatives and Bortezomib on Human Multiple Myeloma Cells, Anna Staskiewicz

Theses/Dissertations from 2021


Investigating the Behavioral and Neuronal Effects of Electric Stimulation of the Cerebellar Cortex Using Awake Mice, Madison Cohen

The effects of Pyrococcus furiosus superoxide reductase and protein kinase C peptide modulators on hypoxia/reoxygenation–induced cell death in human umbilical vein endothelial cells, Tameka C.V. Dean


The Effect of Cardiopulmonary Disease on Lymph Node Hyperplasia and Structural Deviations, Yuhyun Kang

Chronic Methamphetamine Alters Neural Oscillations and Population Spikes Associated with Synaptic Plasticity, thus Long- Term Potentiation in the Guinea Pig Hippocampus, in vivo, Jaclyn Locigno

Ruthenium Substituted, NGR-Tagged Rubredoxin: A Potential Targeted Drug Therapy for Cancer, Brandi N. Muldrow


The Effects of Lycopene and the Mediterranean Diet on Prostate Cancer: A Systematic Review, Natalie Alexis Silk


Allicin stimulates the phosphorylation of eNOSSer1177 via a PI3K-dependent mechanism in type-I diabetic donor coronary artery endothelial cells, Hunter Alberto Vásquez

Theses/Dissertations from 2020

β-2 Adrenergic Agonists Relax Airway Smooth Muscle Cells Through BKCa Channel Activation in a PKA- and PKG- Dependent Mechanism, Monisha Amin

The Effects of Everolimus and Lonafarnib on Hyperphosphorylated Tau and Mtor in Rat Hippocampal Astrocytes, Crisjana Bellamy

A Functional and Histological Analysis on Oxygen Sensitivity During the Critical Period of Retina Development, Rushil Brahmbhatt

Anti-inflammatory and osteogenic effects of naringenin, Savion Carswell

The Effects of Growth Hormone-Releasing Hormone on Nitric Oxide Production in Human Coronary Arterial Endothelial Cells, Jared Alexander Gordon

Effects of AJAP1 Silencing on Gene Expression Pathways Related to Cell Adhesion, Migration And Epithelial-mesenchymal Transition, Danielle Lapoint

The Role of LCN2 in Modulating Inflammatory and Regenerative Pathways in APAP-induced Acute Liver Failure, Lincy E. Matthew

The Effects of In Vitro Seizure-Like Activity on Actin Capping in Dendritic Spines, Cassidy Nieder

The Role of Secretory Phospholipase A2 (sPLA2) in Mediating the Progression of Injury in Acetaminophen-induced Acute Liver Failure, Najiullah Noor


Establishing a Myocardial Ischemia-Reperfusion Injury Model in Mice and Rats using Left Anterior Descending Artery Ligation and Isolated Heart Experiments, Alexander Papa

The Potential Effects of NGR-Tagged, Ruthenium-Substituted Rubredoxin on APN/CD13- Expressing Cancer Cells, Jai Patel

The Role of Lipocalin 2, an Innate Immune Protein During Auto Inflammatory Disorders, Daryllynn Patterson

Effects of Pterostilbene and OSI-027 on Hyperphosphorylated Tau and mTOR in Rat Hippocampal Astrocytes, Marisela Plascencia


AMPK and mTOR Impose Dualistic Regulation of Mitophagy and Autophagy in In Vitro Models of Prostate Cancer, Brianne Richardson

Synergistic Effects of Methylglyoxal and High Glucose on Cardiac H9C2 Cells, Robinderpal Sandhu


The Role of Autophagy in Hydrogen Peroxide- or Methylglyoxal- induced Cardiac Myocyte Damage, Amogh Sehgal

Anti-myeloma Effects of Xanthohumol on Human Multiple Myeloma Cells in Vitro via Induction of Apoptosis and Activation of AMPK Pathway, Michael Tucker

Theses/Dissertations from 2019

Immune Modulation with Non-thermal Plasma on Chlamydia pneumoniae Infected Respiratory Epithelial Cells, Selli Abdali

Downregulation of Caveolin-1 on Acinar Formation of Mammary Epithelial Cells, Ryan C. Andrew

The Effects of Myristoylated and Transactivating Peptide (TAT) Conjugated P110 in Myocardial Ischemia-reperfusion (I/R) Injury, Israel D. Benjamin


The Effects of Resveratrol on DBC1 & Cadherin Expression in Prostate Cancer, Micah Bower-Kaiser


Topography Study of FIXa: Generation of a Lipid Anchored Molecular Ruler with Attached Inhibitor, Nickolas P. Buchanan

AJAP1 and Epithelial Cell Adhesion in Epicardial and Coronary Vessel Formation, Clayton Bunting

A Novel Role for Reelin in Coronary Vasculogenesis, Timothy Dougherty

The Potential of Ruthenium-substituted, NGR-tagged Rubredoxin to Act as a Cancer Therapeutic Drug, Alina Farah


Analysis of Gene Transcription Changes Following Chlamydia pneumoniae Infection of THPl Monocytes May Have Relevance to Alzheimer's Disease, Desiré Guthier


Herpes Simplex Virus Type 1 and Chlamydia Pneumoniae Co-infection in Human Astrocytes Alter Host Cell Transcription of ADAM10, BACEL and PSEN1, Secretases Implicated in Alzheimer Disease, Sidra Montaha Haque


Allicin Reverses Diabetes-Induced Dysfunction of Human Coronary Artery Endothelial Cells, Daniel Horuzsko


The Role of Autophagy in Myocardial Ischemia/Reperfusion Injury in Isolated Rat Hearts, Aloysius C. Ibe II


Preview Pal: Multimodal Learning Modules Devised to Facilitate Learning and Advance Metacognition in Graduate Students, Cierra Lewis

Protein Kinase Beta II (PKC-βІI) inhibitor exerts cardioprotective effects in Myocardial Ischemia/Reperfusion Injury (MI/R), Christina G. Lipscombe

The Role of Caveolin-1 Deficient Human Mammary Fibroblast on Chemotherapy Resistance in Breast Cancer Cells, Daniel Maysonet

Covalent Tethering of Anti-Microbial Peptides onto Titanium Reduces Bacterial Colonization, Dillon McCourt


Comparing the Efficacy of Pharmacological Preconditioning with Myristic Acid-conjugated, TAT- conjugated and Native Protein Kinase C Epsilon Peptide Activator in Myocardial Ischemia/Reperfusion (MI/R) Models, Anahi McIntyre

Rescue of Osteoarthritic Chondrocyte Phenotype Through Long Term, Three-dimensional, Serum-free Culture, Gregory Morris

Increased Autophagy and Liver Regeneration Protects Lipocalin 2 Knockout Mice from Acetaminophen-induced Acute Liver Failure, Christine J. Okaro

Stress, Inflammation, and Astrodegeneration; Epicatechin And Alpha Lipoic Acid as Dietary Supplements, Olalekan Olorunyomi

Learn to Portion: Effects of a Nutrition and Behavioral Intervention on Adults Seeking Healthier Lifestyles, Whitney Otto


Isolation and Characterization of Soil Bacteria from Radium Springs, GA, and Analysis of Antibiotic Secretions Under Various Conditions, Vashishtha D. Patel

The Effects of Co-culturing on In Vitro Soil Bacterial Cultivability and the Discovery of Novel Antibiotics, Syara I. Slaughter

Role of AJAPl in Epithelial Cell Proliferation and Apoptosis for Cardiovascular Development, Amanda Stella

Theses/Dissertations from 2018

Generation of a Sandwich Based 3D Hydrogel to Support Human Mammary Fibroblast Viability and Proliferation, Anna Rebecca Abbott


The Role of Endothelial Nitric Oxide Synthase (eNOS) Coupling Status During Acute Hyperglycemia as Determined by Real-time Measurements of Blood Nitric Oxide And Hydrogen Peroxide in Rat, Matthew Bertolet

Mechanically Tuned Sandwich Based 3D Hydrogels for Investigating the Fibroblast to Myofibroblast Transition, Jana Byrd

Sub-Epithelial Lesions in Esophagogastroduodenoscopies (EGD) and Endoscopic Ultrasound: Epidemiology and Analysis, David Hanna

Eliciting the Apoptotic Mechanism of Ruthenium-Substituted, NGR-Tagged Rubredoxin on CD13-Expressing Cancer Cells, Taylor Shawn Harper

Human Milk Oligosaccharide LNnT as a Novel Anti-Obesity Agent, Meredith E. Hawkins

Potential Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) Against H202-Induced Oxidative Stress in Cardiac H9c2 Cells Compared To Common Antioxidants, Dylan Lefkowitz

The Role of Myo/Nog Cells During the Pathogenesis of Rheumatoid Arthritis, María J. López Garcia

Functional Role of Lipocalin2 During The Progression of Obesity, Keya R. Meyers

Structure Activity Relationship of CAPE and Its Derivatives on Liver Carcinoma Cells, Julie Nguyen

The Combined Effects of Matrix Stiffness and TGF-β on the Acquisition of a Myofibroblast Phenotype in 3D Encapsulated Human Mammary Fibroblasts, Mahtab Parham

Optimizing a Human Osteoarthritic Articular ChondrocyteCulture System as a Test Platform for Therapeutics: A Pilot Study Comparing Extracellular Matrix Protection Factor 1 to Its Hyaluronic Acid Conjugated Counter Part, Hannah Popper


Effect of Putative MitokATP Channel Blocker on Lipopolysaccharide-induced Effects in Human Umbilical Vein Endothelial Cells, Indranie Ramsaroop

Mechanisms of Lipocalin-2 (Lcn2) in Mediating Progression of Acetaminophen-Induced Acute Liver Failure, E'Joven Reed

Anti-Cancer Effect of 2-cyano-3,12 dioxoolean-1,9-dien-28-oic acid (CDDO) Derivatives on Human Multiple Myeloma Cells, Lanerica James Rogers

BKCa Channel Expression and Functional Regulation in Type II Diabetic Human Pulmonary Arterial Smooth Muscle Cells, Mojisola Salau

Investigating the Links Between Early-life Seizures, Stress, and Behavior in a Larval Zebrafish Model, Harsimran Singh

Theses/Dissertations from 2017


Reduction of Opioid Medication Use in Chronic Pain Patients by Adding Memantine: A Pilot Study, Adam J. Bertino

Reelin Signaling in Coronary Vasculogenesis, Alex Bueker

Anti-Cancer Effect of Fluorinated Caffeic Acid Phenethyl Ester in Human Multiple Myeloma Cells, Elizabeth Hernandez Marin

Prostaglandin E2 Receptor: A Novel Target Attenuates Excessive Bone Loss During Autoimmune Arthritis, Aleksandra Ignatowicz

The Role of Caveolin-1 Deficient Human Mammary Fibroblasts in Chemotherapy Resistance in Breast Cancer Cells, Katherine Keck

The Role of Lipocalin-2 (Lcn2) in Acetaminophen-Induced Acute Liver Failure, Christina Paul


Novel Anti-Obesity Effects of Beer Hops Compound Xanthohumol: Role of Ampk Signaling Pathway, Janaiya S Samuels

Analysis of the Effects of Tgf-β Mediated Reduction of Caveolin-1 Expression Following Fibroblast Interaction with a Biological Extracellular Matrix, Shelby Sweat

A Study of the Relationship Between the Long Noncoding RNA PRNCR1, PCGEM1, and Androgen Receptor Transcriptional Activity, Peter Wieczorek


The Role of NADPH Oxidase Isoform 1 (NOX1) in L-NAME-Induced Leukocyte-Endothelial Interactions in Rat Mesenteric Postcapillary Venules, Alita Zabrecky

Theses/Dissertations from 2016

The Multifaceted Effects of Guggulsterone as an Anti-Obesity Agent, Yusra Azhar

Potential Therapeutic Efficacy of a Novel Metalloproteinase Inhibitor, Extracellular Matrix Protection Factor 1, in Human Osteoarthritic Chondrocyte Primary Cultures, Andrea Buckley

Estrogen Regulation of Cell Adhesion Molecules, Affecting Monocyte and Endothelial Cell Interactions, Nikole Marie Czapp

Determining the Efficacy of Antibiotic Stewardship Programs in the Metropolitan Atlanta Area: The Need to Identify Quantifiable Measures for Success, Sueaen Q. Daly

The Potential for Ruthenium-Substituted Rebredoxin with Attached Tumor-Homing Peptide NGR as a Selective Cancer Therapeutic Drug, Alexandra Hill