Full text of theses are available on the DigitalCommons with permission of the student author and faculty advisor.
Any request to obtain the full text of a thesis by a previous PCOM student that is not on the DigitalCommons should be directed to the author or authors directly, as we are not authorized to provide that material on their behalf.
Theses/Dissertations from 2018
Functional Role of Lipocalin2 During The Progression of Obesity, Keya R. Meyers
Structure Activity Relationship of CAPE and Its Derivatives on Liver Carcinoma Cells, Julie Nguyen
Effect of Putative MitokATP Channel Blocker on Lipopolysaccharide-induced Effects in Human Umbilical Vein Endothelial Cells, Indranie Ramsaroop
Mechanisms of Lipocalin-2 (Lcn2) in Mediating Progression of Acetaminophen-Induced Acute Liver Failure, E'Joven Reed
Anti-Cancer Effect of 2-cyano-3,12 dioxoolean-1,9-dien-28-oic acid (CDDO) Derivatives on Human Multiple Myeloma Cells, Lanerica James Rogers
BKCa Channel Expression and Functional Regulation in Type II Diabetic Human Pulmonary Arterial Smooth Muscle Cells, Mojisola Salau
Investigating the Links Between Early-life Seizures, Stress, and Behavior in a Larval Zebrafish Model, Harsimran Singh
Theses/Dissertations from 2017
Reduction of Opioid Medication Use in Chronic Pain Patients by Adding Memantine: A Pilot Study, Adam J. Bertino
Reelin Signaling in Coronary Vasculogenesis, Alex Bueker
Anti-Cancer Effect of Fluorinated Caffeic Acid Phenethyl Ester in Human Multiple Myeloma Cells, Elizabeth Hernandez Marin
Prostaglandin E2 Receptor: A Novel Target Attenuates Excessive Bone Loss During Autoimmune Arthritis, Aleksandra Ignatowicz
The Role of Caveolin-1 Deficient Human Mammary Fibroblasts in Chemotherapy Resistance in Breast Cancer Cells, Katherine Keck
The Role of Lipocalin-2 (Lcn2) in Acetaminophen-Induced Acute Liver Failure, Christina Paul
Novel Anti-Obesity Effects of Beer Hops Compound Xanthohumol: Role of Ampk Signaling Pathway, Janaiya S Samuels
A Study of the Relationship Between the Long Noncoding RNA PRNCR1, PCGEM1, and Androgen Receptor Transcriptional Activity, Peter Wieczorek
The Role of NADPH Oxidase Isoform 1 (NOX1) in L-NAME-Induced Leukocyte-Endothelial Interactions in Rat Mesenteric Postcapillary Venules, Alita Zabrecky
Theses/Dissertations from 2016
The Multifaceted Effects of Guggulsterone as an Anti-Obesity Agent, Yusra Azhar
Estrogen Regulation of Cell Adhesion Molecules, Affecting Monocyte and Endothelial Cell Interactions, Nikole Marie Czapp
The Potential for Ruthenium-Substituted Rebredoxin with Attached Tumor-Homing Peptide NGR as a Selective Cancer Therapeutic Drug, Alexandra Hill
Osteogenic Factors: Novel Targets to Attenuate Excessive Bone Degradation during Autoimmune Arthritis, Lauren Z. Holland
Herpes Simplex Virus Type 1 and Chlamydia Pneumoniae Infection of Astrocytes: The Effects of Co-Infection on Pathogen Replication, Syed Rasikh Ali Jaffery
The Relationship of Chlamydia antigen, AD-Like Pathology, and Inflammation in the Brains of Intranasally Infected BALB/c Mice, Brittany L. Kane
Reelin Signaling in Cardiovascular Development, Dongwook Kim
The Implications of CsA Treatment on Renal Fibrosis: An Examination of in vivo and in vitro miR and mRNA Changes Affecting the TGFB Pathway, Clayton Maxwell King
Effects of NOX-1 Inhibition on Real-Time Blood Nitric Oxide and Hydrogen Peroxide in Acute Hyperglycemia, Ashley Mawhinney
Generation of Stable, Long-Term Cultures of Experimentally Induced Myofibroblasts from Co-Cultures of Human Mammary Fibroblasts with Breast Cancer Cells, Brittany Melvin
BKCa Channel Expression and Functional Regulation In Type 1 Diabetic Human Pulmonary Artery Smooth Muscle Cells, Brigitte M. Meyers
Mass Culturing Soil Bacteria from Radium Springs and Analysis of Antibiotic Activity, Amanda Nguyen
Determining the Effect of Targeting Androgen Receptor Acetylation in Prostate Cancer, Victoria Nolte
Phytochemical Induced Polarization of Macrophages: Implications on Obesity, Ashish Parmar
Protaglandin EP2 Receptor Antagonism: a Novel Approach to Attenuate/Prevent the Inflammation during Auto-Inflammatory Disorders, Austin C. Russell
Effects of Hormonal Withdrawal on Prostate Cancer Progression, Jacqueline Chakrya So
Loss of Stromal Caveolin-! Expression and Introduction of Exogenous Biofactors Alters ECM Protein Composition and Ductal Formation in Murine Mammary Glands, Christopher M. Thompson
Osteopathic Manipulative Treatment for Infants in the NICU: A Systematic Review, Hunter Jaclyn Wernick
Developing a Model System to Study the Mechanisms of Resveratrol Inhibition of AR-V7 Transcriptional Activity, Sarah R. Wilson
The Effects of Estrogen on Endothelial Dysfunction in Diabetes, Jessica Winkler
Theses/Dissertations from 2015
Function of Long-Term Depression in Purkinje Cells to Regulate Excitability to a New Equilibrium, Gulsedef Arslan
Use of Swine Small Intestine Submucosa as a Dermal Suture, Paige E. Black
The Effects of Omega-3 Fatty Acids & Cyclic Adenosine Monophosphate on Transcription of Genes Involved in Arginine Metabolism, Vamsee K. Duggirala
The Mediation of Insulin on Combined Effects of Fetal Astrocytic Hypoxia and Zinc, Dakita Mack
Stress, Inflammation, Cancer and Dementia; CDDO and Curcumin as Therapeutic Agents, Peter Pham
Do Predictive Factors for Post-Traumatic Stress Disorder Elucidate the Variable Prevalence Rates Between National Guard/Reserve Soldiers and Active Duty Soldiers?, Shannon Marie Philipps
Are New Sodium Targets in the National School Lunch Program Feasible and Are They Necessary?, Yaneve Shemesh
Associations between First Year Medical Students' Lifestyles, Resting Blood Pressure, and Resting ECGs, Christina Marie Spino
MDIVI-1, A Mitochondrial Division Inhibitor, Exerts Cardioprotective Effects in Myocardial Ischemia/Reperfusion (MI/R) when Given at Reperfusion, Devon P. Stutzman
Covalent Attachment of Antibiotics to Bone Allograft, Nickolas Swisher
The Influence of Matrix Stiffness on Acquisition of a Myofibroblast Phenotype in 3D Encapsulated Human Mammary Fibroblasts, Catlyn Thigpen
Enhanced cGMP-Dependent Signaling in Astrocytes: Novel Therapeutic Target in Alzheimer's Disease, Nyema M. Woart
The Influence of Matrix Stiffness on Extracellular Matrix Protein Expression in 3D Encapsulated Mammary Fibroblasts, Kathryn Woods
Theses/Dissertations from 2014
Effect of Triage-Based Application of the Ottawa Foot and Ankle Rules on Treatment in an Emergency Department: A Pilot Study, John V. Ashurst
Adipose Derived Stem Cells (ADSC) Harvested from Lipoaspirate Differentiate into Chondrocytes and Osteoblasts, Dimitry Belogorodsky
Assessing Effectiveness of Osteopathic Manipulative Treatment on Lateral Spinal Curvatures Using 2D Morphometrics, Michael J. Bova
Combinatorial Effects of Apocynin (apo) and Mitoquinone (mitoQ) in Treatment of Myocardia Ischemia/Reperfusion (MI/R) Injury, William Chau
Characterization of Lipid-Anchored Inhibitor Rulers as a Measure of Enzyme Topography in Coagulation Enzyme Factor Xa, Robin C. Conley
The Effects of Dihydrobiopterin and Tetrahydrobiopterin on Hydrogen Peroxide and Nitric Oxide Release During Extracorporeal Shockwave Lithotripsy (ESWL), Brittany Deiling
Use of Pyrococcus Furiosus Rubredoxin as a Potential Targeted Cancer Therapeutic, Danielle Elise Frieson
An Analysis of Abnormal Electrocardiograms in First and Second Year Medical School Students, Molly Anne Kalish
Osteopathic Manipulative Medicine (OMM) and Reduction of NSAID Use in Low Back Pain: A Pilot Study, Kristopher Kelly
Effectiveness of Osteopathic Manipulative Treatment and/or Patient-Directed Self Care in Managing Tension Headaches, Thomas Matthew Lettich
Potential Anti-Dementia Chemicals: Preventing APOE and NF-kB Release in Astrocyte Culture, Kingsley Njoku
Effect of Tumor Necrosis Factorα on Expression of Heme-Oxgenase1 in Human Gingival Fibroblasts, Jay Patel
Effect of Heme Oxygenase-1 on Matrix Metalloproteinase-3 Expression in Human Fibroblasts, Theresa A. Stangl
Microscopic Analysis of Two Glands Involved in Osmoregulation in Elasmobranchs: The Rectal Salt and Interrenal Glands of Dasyatis sabina, Tomeka F. Taylor
Cyclic Nucleotide-Dependent Phosphorylation Regulates BK-Ca Channel Activity in Human Coronary Artery Smooth Muscle Cells, Raeonda Williams
Chemopreventive Effects of Pterostilbene in Metastatic Prostate Cancer Cells, Phillip A. Zook
Theses/Dissertations from 2013
The Effect of Nerve Growth Factor (NGF) Incorporation into Swine Intestinal Submucosa (SIS) Suture Material on the Healing Process in Gastrocnemius Muscle, Nicole K. Alexander
Investigation of Mouse Hepatitis Virus Entry Using Small Interfering RNA Technology, Kristina A. Cade
Chlamydia pneumoniae Infection of Neuronal Cells Induces Changes in Calcium-Associated Gene Expression Consistent with Alzheimer's Disease, Christopher Andrew Cappellini
Molecular Mechanisms Related to Endotoxemia in Primary Human Cardiomyocytes in Culture, Atijah J. Collins
Development of Isoleucine Prodrugs of Cytarabine, Anthony L. Cooper Jr.
The Role of Transforming Growth Factor Beta (TGF-β) in the Extracellular Matrix Degradation Characteristic of Post-Traumatic Osteoarthritis, Courtney Kristen Docherty
Estrogen Effect on Manganese-Induced Astrocytic Toxicity, Tyler Huynh
Nutri One-on-One: The Assessment and Evaluation of a Single One-on-One Nutritional Coaching in Patients Affected by Metabolic Syndrome, Jennifer L. King
Mechanisms of Mouse Hepatitis Entry into Cells, Philip J. Koehler
The Effects of Modulating Endothelial Nitric Oxide Synthase Activity and Coupling in Extracorporeal Shock Wave Lithotripsy, Alexandra C. Lopez
Apoptotic Sensitivity in Osteoblasts is Maturation Specific, Dominick V. Mastracco
Clinical Research Challenges: Insight from a Pilot Study at an Academic Healthcare Center, Gretchen E. Maurer
Cardioprotective Effects of Mitochondrial-Targeted Antioxidants in Myocardial Ischemia/Reperfusion (I/R) Injury, Regina Ondrasik
Detection of Chlamydia Pneumoniae in Blood Samples: A Diagnostic Screen for Alzheimer Disease, Lauren Elise Semler
Resveratrol Induced Apoptosis in a Human Adenosquamous Carcinoma Cell Line (CAL-27 Cells), Saquib A. Siddiqi
Effect of Nicotine on IL-1 Induced MMP-3 Expression: Role of a Polymorphic Promoter Element, Cynthia Uche
IMP2 Expression in the Mouse Nervous System, Victoria Vlada Vinarsky
A Statistical Test to Assess Tissue Characterization of Abdominal Organs By Color-Fusion MRI, Terrance Darnell Weeden
Detection of Chlamydia Muridarum Antigen and AD-Like Pathology in the Brain Tissue of Intranasally Infected BALB/c Mice, Lindsey Victoria Weidmann
Theses/Dissertations from 2012
Analysis of Inflammasome Gene Regulation Following Chlamydia pneumoniae Infection of THPl Monocytes: Implications for Alzheimer's Disease, Jonathan M. Anzmann
Attachment of Two Antibiotics to a Titanium Alloy Surface to Inhibit Colonization by Gram-positive and Gram-negative Bacteria, Holly Brizell