Splanchnic vascular control during sepsis and endotoxemia.

Document Type

Article

Publication Date

1997

Abstract

Endotoxemia and sepsis often result in circulatory derangements which manifest as perfusion maldistributions. It has been widely accepted that the splanchnic circulation decreases in perfusion during advanced septic or endotoxemic states. Impaired perfusion of splanchnic organs may result not only in organ dysfunction but also exacerbations of polymicrobial bacteremia due to intestinal mucosal leakage. Consequently, evaluation of the splanchnic mechanisms of vasoregulation and how perfusion is maintained is vital to any topic concerning the management of the septic patient.

Publication Title

Frontiers in bioscience : a journal and virtual library

Volume

2

First Page

e72

Last Page

92

Comments

This article was published in Frontiers in bioscience : a journal and virtual library, Volume 2, Pages e72-92.

The published version is available at http://dx.doi.org/10.2741/A229 .

Copyright © 1997 Frontiers in BioScience.

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