Regulation of dendritic development by calcium signaling

Document Type

Article

Publication Date

2005

Abstract

Neuronal activity can have profound effects on dendrite morphology in the developing brain. The effects of neuronal activity on dendritic morphology are mediated by calcium signaling. While many effects of calcium on dendrite structure occur locally at the site of calcium entry into the cytoplasmic milieu, elevation of cytoplasmic calcium is also translated into changes in gene transcription. Decoding the calcium signal into specific changes in gene transcription involve coordinating the action of a number of kinases, phosphatases, transcription factors and transcriptional coactivators. This review focuses on the contribution of calcium-dependent transcription on the control of dendritic morphology. © 2005 Published by Elsevier Ltd.

Publication Title

Cell calcium

Volume

37

Issue

5 SPEC. ISS.

First Page

411

Last Page

416

Comments

This article was published in Cell calcium, Volume 37, Issue 5 SPEC. ISS., Pages 411-416.

The published version is available at http://dx.doi.org/10.1016/j.ceca.2005.01.009.

Copyright © 2005 Elsevier.

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