Antifactor Xa Monitoring in Patients on IV Unfractionated Heparin

Document Type

Article

Publication Date

2015

Abstract

Although the introduction of newer anticoagulants has revolutionized the treatment of venous thromboembolism, IV unfractionated heparin (UFH) continues to be widely prescribed in hospitalized patients because of its pharmacokinetic profile. The activated partial thromboplastin time (aPTT) test has been used to monitor outcomes in patients receiving UFH, but significant issues, such as varying aPTT reagents, instrumentation procedures, and interpatient variability, are associated with the test. Antifactor Xa monitoring of patients on continuous IV UFH may better correlate with heparin concentrations, determine therapeutic ranges for aPTT, and result in fewer testing procedures for patients and personnel. - See more at: http://www.uspharmacist.com/content/c/53562/#sthash.Pl0cVjLK.dpuf

Publication Title

U.S. Pharmacist

Volume

40

Issue

3

First Page

HS26-HS32

Last Page

HS26-HS32

Comments

This article was published in U.S. Pharmacist, Volume 40, Issue 3, Pages HS26-HS32.

The published version is available at http://www.uspharmacist.com/content/c/53562/.

Copyright © 2015 US Pharmacist.

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