Document Type

Article

Publication Date

1-1-2018

Abstract

This article reviews research results and ideas presented at a special symposium at the International Association of Gerontology and Geriatrics (IAGG) Congress held in July 2017 in San Francisco. Five researchers presented their results related to infection and Alzheimer's disease (AD). Prof. Itzhaki presented her work on the role of viruses, specifically HSV-1, in the pathogenesis of AD. She maintains that although it is true that most people harbor HSV-1 infection, either latent or active, nonetheless aspects of herpes infection can play a role in the pathogenesis of AD, based on extensive experimental evidence from AD brains and infected cell cultures. Dr. Miklossy presented research on the high prevalence of bacterial infections that correlate with AD, specifically spirochete infections, which have been known for a century to be a significant cause of dementia (e.g., in syphilis). She demonstrated how spirochetes drive senile plaque formation, which are in fact biofilms. Prof. Balin then described the involvement of brain tissue infection by the

Publication Title

Frontiers in Genetics

Volume

9

PubMed ID

30250480

Comments

This article was published in Frontiers in Genetics, Volume 9.

The published version is available at https://doi.org/10.3389/fgene.2018.00362.

Copyright © 2018 Fülöp, Itzhaki, Balin, Miklossy and Barron. CC BY 4.0.

Included in

Neurology Commons

COinS