Fluorinated Caffeic Acid Phenethyl Ester: a Novel Anti-osteogenic molecule to Attenuate Excessive Bone Damage during Autoimmune Arthritis

Authors

Lauren Holland, Philadelphia College of Osteopathic MedicineFollow
Ramanjaneya V.R. Mula
Deepa Machiah
Xinyu Wang, Philadelphia College of Osteopathic MedicineFollow
Rangaiah Shashidharamurthy, Philadelphia College of Osteopathic MedicineFollow

Document Type

Article

Publication Date

2016

Abstract

Caffeic Acid Phenethyl Ester (CAPE), an antioxidant flavonoid isolated from hives of honeybee, is reported to exert its anti-osteogenic function by inhibiting the NF-kB activation. It also disrupts the microtubule network created by osteoclasts, which wou

Publication Title

The FASEB Journal

Volume

30

Issue

1 Supplement

First Page

lb451

Last Page

lb451

Comments

This meeting abstract was published in The FASEB Journal, Volume 30, Issue 1 Supplement, Pages lb451-lb451.