Location
Moultrie, GA
Start Date
17-4-2026 12:00 PM
End Date
17-4-2026 1:00 PM
Description
INTRODUCTION: Premenstrual Dysphoric Disorder (PMDD) can cause the affected person’s debilitating pain, depression, and mood swings in a manner that is consistently associated with their menstrual cycle. PMDD is classified as a psychiatric disorder with its criteria outlined in the DSM-5. The etiology is unclear, but some risk factors include anxiety disorders, obesity, and cigarette smoking. Our case centers around a 44-year-old woman diagnosed with PMDD and treated by hysterectomy with bilateral salpingo-oophorectomy as a potential cure for her diagnosis. Her treatment journey was riddled with misdiagnoses, failed medical therapies, and emotional turmoil. By contributing to the knowledge about PMDD, we hope to mitigate barriers to effective treatment and help elucidate some of the mysteries around PMDD etiology and potential cures.
METHODS: We compiled research on PMDD articles and the medical records of our patient to provide an overview of PMDD, its etiology, and treatment options.
RESULTS: In this case, the patient did not respond to standard therapies, including Yaz and Seasonique, both of which resulted in poor bleeding control. The patient continued to have impairments in her daily life, leading to depression, anxiety, and both suicidal ideation and attempts. As a result, the decision was made to transition to surgical management. Since recovering from the surgery, the patient has not experienced cyclical mood symptoms and has seen an immense improvement in the quality of life. This indicates the life-altering role a TH-BSO has and the need for early recognition when the patient is not responsive to prescribed therapies. This case will be presented as a poster at PCOM-SGA’s Research Day 2026.
CONCLUSION: This case underscores the importance of individualized, patient-centered care and identifies potential barriers to managing severe, treatment-refractory PMDD. When standard therapies fail to provide relief, hysterectomy with bilateral salpingo- oophorectomy (TH-BSO) may serve as a definitive treatment option to restore quality of life.
Embargo Period
5-29-2026
Included in
A Radical Response to PMDD: When Hysterectomy Becomes the Answer
Moultrie, GA
INTRODUCTION: Premenstrual Dysphoric Disorder (PMDD) can cause the affected person’s debilitating pain, depression, and mood swings in a manner that is consistently associated with their menstrual cycle. PMDD is classified as a psychiatric disorder with its criteria outlined in the DSM-5. The etiology is unclear, but some risk factors include anxiety disorders, obesity, and cigarette smoking. Our case centers around a 44-year-old woman diagnosed with PMDD and treated by hysterectomy with bilateral salpingo-oophorectomy as a potential cure for her diagnosis. Her treatment journey was riddled with misdiagnoses, failed medical therapies, and emotional turmoil. By contributing to the knowledge about PMDD, we hope to mitigate barriers to effective treatment and help elucidate some of the mysteries around PMDD etiology and potential cures.
METHODS: We compiled research on PMDD articles and the medical records of our patient to provide an overview of PMDD, its etiology, and treatment options.
RESULTS: In this case, the patient did not respond to standard therapies, including Yaz and Seasonique, both of which resulted in poor bleeding control. The patient continued to have impairments in her daily life, leading to depression, anxiety, and both suicidal ideation and attempts. As a result, the decision was made to transition to surgical management. Since recovering from the surgery, the patient has not experienced cyclical mood symptoms and has seen an immense improvement in the quality of life. This indicates the life-altering role a TH-BSO has and the need for early recognition when the patient is not responsive to prescribed therapies. This case will be presented as a poster at PCOM-SGA’s Research Day 2026.
CONCLUSION: This case underscores the importance of individualized, patient-centered care and identifies potential barriers to managing severe, treatment-refractory PMDD. When standard therapies fail to provide relief, hysterectomy with bilateral salpingo- oophorectomy (TH-BSO) may serve as a definitive treatment option to restore quality of life.