Predictors of in-hospital mortality and readmission rates in superior vena cava syndrome patients
Location
Philadelphia, PA
Start Date
11-5-2022 1:00 PM
End Date
11-5-2022 4:00 PM
Description
Introduction
Superior Vena Cava syndrome (SVCS) is commonly caused by external compression of the vessel wall by thoracic malignancies or from an occlusion in the SVC. The most commonly performed interventional treatments of SVCS include catheter-directed thrombolysis, endovascular stenting, and thrombectomy. No studies have determined predictive factors of mortality or 30-day readmission rates in patients with SVCS.
Methods
Using the National Readmission Database for years 2016 through 2019, patients with a discharge diagnosis of SVCS were identified using the International Classification of Diseases, Tenth Revision (ICD-10). Out of this group of patients, ICD-10 codes were used to identify a variety of comorbidities in order to investigate their impact on in-hospital mortality and 30-day readmission rates. We identified predictors of in-hospital mortality and 30-day readmission with univariate logistic regression analysis followed by multivariate logistic regression for variables approaching significance.
Results
Out of 774 patients with SVCS, the in-hospital mortality rate was 3.1%. A pulmonary embolism (PE) in a patient with SVCS was associated with a significantly higher risk of mortality (OR 3.20; 95% CI 1.1- 9.4; p = 0.035). PE occurred in 9.4% of SVCS patients. Overall, 22.1% of patients with SVCS had an unplanned readmission within 30 days of initial discharge. PE was found to also be a predictor of 30-day readmission in SVCS patients (OR 1.91; 95% CI 1.1-3.4; p = 0.029). The use of interventional treatments in patients with SVCS showed a decreased risk of readmission within 30 days (OR 0.63; 95% CI 0.41-0.95; p= 0.030).
Conclusions
This nationwide observational study showed in-hospital mortality and 30-day readmission rates are high in SVCS patients. PE in patients with SVCS was a strong predictor of in-hospital mortality and 30-day readmission. Interventional treatment was associated with lower rehospitalization rates in these patients.
Embargo Period
5-26-2022
Predictors of in-hospital mortality and readmission rates in superior vena cava syndrome patients
Philadelphia, PA
Introduction
Superior Vena Cava syndrome (SVCS) is commonly caused by external compression of the vessel wall by thoracic malignancies or from an occlusion in the SVC. The most commonly performed interventional treatments of SVCS include catheter-directed thrombolysis, endovascular stenting, and thrombectomy. No studies have determined predictive factors of mortality or 30-day readmission rates in patients with SVCS.
Methods
Using the National Readmission Database for years 2016 through 2019, patients with a discharge diagnosis of SVCS were identified using the International Classification of Diseases, Tenth Revision (ICD-10). Out of this group of patients, ICD-10 codes were used to identify a variety of comorbidities in order to investigate their impact on in-hospital mortality and 30-day readmission rates. We identified predictors of in-hospital mortality and 30-day readmission with univariate logistic regression analysis followed by multivariate logistic regression for variables approaching significance.
Results
Out of 774 patients with SVCS, the in-hospital mortality rate was 3.1%. A pulmonary embolism (PE) in a patient with SVCS was associated with a significantly higher risk of mortality (OR 3.20; 95% CI 1.1- 9.4; p = 0.035). PE occurred in 9.4% of SVCS patients. Overall, 22.1% of patients with SVCS had an unplanned readmission within 30 days of initial discharge. PE was found to also be a predictor of 30-day readmission in SVCS patients (OR 1.91; 95% CI 1.1-3.4; p = 0.029). The use of interventional treatments in patients with SVCS showed a decreased risk of readmission within 30 days (OR 0.63; 95% CI 0.41-0.95; p= 0.030).
Conclusions
This nationwide observational study showed in-hospital mortality and 30-day readmission rates are high in SVCS patients. PE in patients with SVCS was a strong predictor of in-hospital mortality and 30-day readmission. Interventional treatment was associated with lower rehospitalization rates in these patients.