Event Title
The Effects of Depression and Anti-depressants on Patient Satisfaction after Breast Reconstruction
Location
Philadelphia, PA
Start Date
8-5-2019 1:00 PM
End Date
8-5-2019 4:00 PM
Description
Background: A personal history of depression prior to a breast cancer diagnosis and its effect on post-diagnosis quality of life (QOL) in women undergoing breast reconstruction is relatively unknown. We performed the current study to determine if depression alters QOL for patients who undergo breast reconstruction by assessing the pre-to-post-operative change in patient-reported BREAST-Q scores.
Methods: This study is a single-center, post-hoc analysis of 300 patients with completed BREAST-Q data who underwent breast reconstruction following a diagnosis of breast cancer from November 2013 to 2016. Patients completed the BREAST-Q at four time points: pre-operatively, 6-weeks following tissue expander insertion for patients undergoing staged reconstruction, 6-months following final reconstruction, and 12-months following final reconstruction. Medical records of breast reconstruction patients were reviewed to identify patients who had a pre-cancer diagnosis of clinical depression and/or anti-depressant medication use. BREAST-Q scores were compared between the depression (n=50) and no depression (n=250) patients, along with anti-depressant (n=36) and no anti-depressant (n=14) use in the depression group.
Results: The Sexual Well-being scores at the 6-week tissue expander follow up for patients in the depression group (median = 37, IQR = 25-47) were significantly lower (p<0.01) than the scores for patients in the no depression group (median = 47, IQR = 39-60) following adjusted analysis. There were no statistically significant differences in BREAST-Q scores in other domains.
Conclusion: Patients with a diagnosis of depression prior to breast cancer had lower BREAST-Q Sexual Well-being scores in the 6-week tissue expander group with or without anti-depressant medication. No differences in BREAST-Q scores were observed among the remaining domains, although Satisfaction of Breasts: 6-months post-op, Psychosocial Well-being: 6-weeks post TE, Sexual Well-being: 6-weeks post TE and 6-months post-op were clinically significant.
Embargo Period
5-24-2019
The Effects of Depression and Anti-depressants on Patient Satisfaction after Breast Reconstruction
Philadelphia, PA
Background: A personal history of depression prior to a breast cancer diagnosis and its effect on post-diagnosis quality of life (QOL) in women undergoing breast reconstruction is relatively unknown. We performed the current study to determine if depression alters QOL for patients who undergo breast reconstruction by assessing the pre-to-post-operative change in patient-reported BREAST-Q scores.
Methods: This study is a single-center, post-hoc analysis of 300 patients with completed BREAST-Q data who underwent breast reconstruction following a diagnosis of breast cancer from November 2013 to 2016. Patients completed the BREAST-Q at four time points: pre-operatively, 6-weeks following tissue expander insertion for patients undergoing staged reconstruction, 6-months following final reconstruction, and 12-months following final reconstruction. Medical records of breast reconstruction patients were reviewed to identify patients who had a pre-cancer diagnosis of clinical depression and/or anti-depressant medication use. BREAST-Q scores were compared between the depression (n=50) and no depression (n=250) patients, along with anti-depressant (n=36) and no anti-depressant (n=14) use in the depression group.
Results: The Sexual Well-being scores at the 6-week tissue expander follow up for patients in the depression group (median = 37, IQR = 25-47) were significantly lower (p<0.01) than the scores for patients in the no depression group (median = 47, IQR = 39-60) following adjusted analysis. There were no statistically significant differences in BREAST-Q scores in other domains.
Conclusion: Patients with a diagnosis of depression prior to breast cancer had lower BREAST-Q Sexual Well-being scores in the 6-week tissue expander group with or without anti-depressant medication. No differences in BREAST-Q scores were observed among the remaining domains, although Satisfaction of Breasts: 6-months post-op, Psychosocial Well-being: 6-weeks post TE, Sexual Well-being: 6-weeks post TE and 6-months post-op were clinically significant.