Location
Philadelphia, PA
Start Date
9-5-2018 1:00 PM
Description
When wound healing of cutaneous tissue becomes problematic, it increases patient morbidity associated with increased infection, demand on medical resources, and asserts a profound detrimental effect on the individual’s quality of life. Currently, there are limited effective strategies for addressing chronic cutaneous wounds. The study reported here is based upon the understanding that individual skin wounds may preferentially require differing proteinaceous precursors during specific phases of skin wound repair and calls attention to the possibilities in the reexamination of traditional treatments such as plant and animal-derived substances among many others. This study aimed to determine if, and which, amino acid containing powders could be applied to wounds and lead to faster or more effective healing when compared to a similar wound in the same animal. These compounds were chosen based upon their predetermined roles in wound healing processes like clotting and scar formation. Size of wound in addition to histological features were measured and included number of immune cells such as fibroblasts, fat cells and dense connective tissue. This data showed certain amino acid powders did have preferential healing in these types of wounds. It presents preliminary data that suggests this approach may offer new resources to address this increasingly widespread medical issue.
Embargo Period
5-30-2018
Bioactive Peptides™ to Aid in Healing of Chronic Skin Wounds and Tissue Repair
Philadelphia, PA
When wound healing of cutaneous tissue becomes problematic, it increases patient morbidity associated with increased infection, demand on medical resources, and asserts a profound detrimental effect on the individual’s quality of life. Currently, there are limited effective strategies for addressing chronic cutaneous wounds. The study reported here is based upon the understanding that individual skin wounds may preferentially require differing proteinaceous precursors during specific phases of skin wound repair and calls attention to the possibilities in the reexamination of traditional treatments such as plant and animal-derived substances among many others. This study aimed to determine if, and which, amino acid containing powders could be applied to wounds and lead to faster or more effective healing when compared to a similar wound in the same animal. These compounds were chosen based upon their predetermined roles in wound healing processes like clotting and scar formation. Size of wound in addition to histological features were measured and included number of immune cells such as fibroblasts, fat cells and dense connective tissue. This data showed certain amino acid powders did have preferential healing in these types of wounds. It presents preliminary data that suggests this approach may offer new resources to address this increasingly widespread medical issue.