Localization of Laminin Relative to Alpha 1 Integrin in Embryonic Chick Skeletal Muscle

Location

Philadelphia Campus

Start Date

2-5-2012 2:00 PM

End Date

2-5-2012 4:00 PM

Description

Background:The spatial and temporal localization of laminin in relation to alpha 1 integrin is examined in chick skeletal muscle. Periodic colocalization of alpha 1 integrin and laminin have previously been observed on myofibers in cultured embryonic chick skeletal muscle as early as day 3 in culture. Similar to the spatial localization found in cultured skeletal muscle, alpha 1 integrin is found with a periodic sarcomeric distribution in sectioned skeletal muscle from chick embryos beginning on embryonic day 13.

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May 2nd, 2:00 PM May 2nd, 4:00 PM

Localization of Laminin Relative to Alpha 1 Integrin in Embryonic Chick Skeletal Muscle

Philadelphia Campus

Background:The spatial and temporal localization of laminin in relation to alpha 1 integrin is examined in chick skeletal muscle. Periodic colocalization of alpha 1 integrin and laminin have previously been observed on myofibers in cultured embryonic chick skeletal muscle as early as day 3 in culture. Similar to the spatial localization found in cultured skeletal muscle, alpha 1 integrin is found with a periodic sarcomeric distribution in sectioned skeletal muscle from chick embryos beginning on embryonic day 13.