DigitalCommons@PCOM - Research Day: IMP2 Expression In The Mouse Nervous System
 

Location

Georgia Campus

Start Date

2-5-2012 2:00 PM

End Date

2-5-2012 4:00 PM

Description

Background: Insulin-like growth factor-II (IGF-II) mRNA-binding protein-2 (IMP2) is one of the three homologs (IMP1-3) that play important roles in the posttranscriptional regulation of gene expression in several tissues. IMP1/ZBP1 (zipcode binding protein) has been shown to play important roles in axon guidance and regeneration by regulating the localization and translation of specific mRNAs. However, the function of IMP2 is least understood, largely because an isoform-specific antibody is not available, which makes the conventional techniques to locate protein expression not feasible.

Chmielewski.pdf (831 kB)
Poster

Chiemelewsksi_abstract.pdf (58 kB)
Abstract

COinS
 
May 2nd, 2:00 PM May 2nd, 4:00 PM

IMP2 Expression In The Mouse Nervous System

Georgia Campus

Background: Insulin-like growth factor-II (IGF-II) mRNA-binding protein-2 (IMP2) is one of the three homologs (IMP1-3) that play important roles in the posttranscriptional regulation of gene expression in several tissues. IMP1/ZBP1 (zipcode binding protein) has been shown to play important roles in axon guidance and regeneration by regulating the localization and translation of specific mRNAs. However, the function of IMP2 is least understood, largely because an isoform-specific antibody is not available, which makes the conventional techniques to locate protein expression not feasible.