Date of Award

2020

Degree Type

Selective Evidence-Based Medicine Review

Degree Name

Master of Science in Health Sciences - Physician Assistant

Department

Physician Assistant Studies

Abstract

OBJECTIVE: The objective of this systematic review is to determine whether or not bimatoprost 0.03% improves satisfaction in patients at least 12 years old with eyelash hypotrichosis.

STUDY DESIGN: Systematic review of three multicenter, double-masked, randomized, parallel group studies, all published in English between 2015 and 2016.

DATA SOURCES: All three studies used in this review were researched via PubMed and were published in peer-reviewed journals.

OUTCOMES MEASURED: Patient satisfaction was measured using the Eyelash Satisfaction Questionnaire (ESQ) in all three studies.

RESULTS: Wirta et al. (J Clin Aesthet Dermatol. 2015;8:11–20.) found a statistically significant relationship between bimatoprost 0.03% and satisfaction with a p=0.004. Borchert et al. (Clin Ophthalmol. 2016;10:419-29. doi:10.2147/OPTH.S89561) did not indicate a p-value but 78.2% of subjects treated with bimatoprost 0.03% and 65% of subjects in the control were found to have an increase in satisfaction of eyelash growth at the end of the study. The study conducted by Glaser et al. (Br J Dermatol. 2015;172(5):1384-94.) did not find a statistically significant relationship between bimatoprost 0.03% and satisfaction with p=0.25.

CONCLUSIONS: The results of these studies show that the objective question remains inconclusive in regard to increasing patient satisfaction after the use of bimatoprost 0.03% as only one out of the three studies showed a statistically significant relationship. Further studies should be conducted with researchers not employed by the pharmaceutical company who manufactures the product.

Download

Share

COinS