Date of Award

2019

Degree Type

Selective Evidence-Based Medicine Review

Degree Name

Master of Science in Health Sciences - Physician Assistant

Department

Physician Assistant Studies

Department Chair

Laura Levy, DHSc, PA-C

Abstract

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Do adults undergoing minimally invasive quadriceps-sparing total knee arthroplasty have less of a risk of developing a postoperative deep venous thrombosis as compared to patients undergoing a standard medial parapatellar total knee arthroplasty?”

STUDY DESIGN: A review of one case series published in 2007 and two randomized controlled trials published in 2014.

DATA SOURCES: Primary literature found in PubMed that compared the surgical outcomes of minimally invasive quadriceps-sparing total knee arthroplasty to standard medial parapatellar total knee arthroplasty.

OUTCOME MEASURED: Postoperative deep venous thrombosis development.

RESULTS: All three studies reported that zero patients that received the minimally invasive surgery developed a DVT. In each study, at least one patient that received the standard surgery developed a DVT. In King et al., 4 patients who received the standard medial parapatellar total knee arthroplasty developed a DVT. In both Tasker et al. and Tomek et al. 1 patient who received the standard medial parapatellar total knee arthroplasty developed a DVT.

CONCLUSIONS: Although further research needs to be done to make a general statement, there is some evidence, based on the information in the studies reviewed, that adults undergoing minimally invasive quadriceps-sparing total knee arthroplasty have less of a risk of developing a postoperative deep venous thrombosis as compared to patients undergoing a standard medial parapatellar total knee arthroplasty.

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