Association Between Perceived Threat and the Development of Post-traumatic Stress Disorder Symptoms in Patients with Life-threatening Medical Emergencies

Document Type

Article

Publication Date

10-24-2019

Abstract

BACKGROUND: Our objectives were to test if during a potentially life-threatening medical emergency, perceived threat (a patient's sense of life endangerment) in the emergency department (ED) is common and associated with the subsequent development of posttraumatic stress disorder (PTSD) symptoms.

METHODS: ED-based prospective cohort study in an academic hospital. We included adult patients requiring acute intervention in the ED for resuscitation of a potentially life-threatening medical emergency, defined as respiratory or cardiovascular instability. We measured patient perceived threat in the ED using a validated patient self-assessment measure (score range 0-21, with higher scores indicating greater perceived threat). We performed blinded assessment of PTSD symptoms 30 days after discharge using the Post-traumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders (PCL-5).

RESULTS: Ninety-nine of 113 (88%) patients completed follow up, with 98% reporting some degree of perceived threat, median [interquartile range (IQR)] perceived threat score 12 (6-17), and 72% reported PTSD symptoms in relation to their ED visit, median (IQR) PCL-5 score 7 (0-30). Patients with respiratory instability had higher median (IQR) perceived threat scores [16 (9-18) vs. 9 (6-14)] and PCL-5 scores [10 (2-40) vs. 3 (0-17)] compared to patients without respiratory instability. In a multivariable linear regression model adjusting for potential confounders, greater perceived threat in the ED was independently associated with higher PCL-5 scores, β = 0.79 (95% CI 0.15-1.42). Among the individual perceived threat items, the feeling of helplessness during resuscitation had the strongest association with PCL-5 score, β = 5.24 (95% CI 2.29 - 8.18).

CONCLUSIONS: Perceived threat during potentially life-threatening emergencies is common and independently associated with development of PTSD symptoms. Additional research to test if reduction of perceived threat in the ED attenuates the development of PTSD symptoms following potentially life-threatening emergencies is warranted.

Publication Title

Academic Emergency Medicine

PubMed ID

31650652

Comments

This article was published in Academic Emergency Medicine.

The published version is available at https://doi.org/10.1111/acem.13877

Copyright © 2019 Society for Academic Emergency Medicine.

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