ALS Specific Quality of Life- Short Form (ALSSQOL-SF): A Brief, Reliable and Valid Version of the ALSSQOL-R

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INTRODUCTION: The ALS Specific Quality of Life instrument and its revised version (ALSSQOL, ALSSQOL-R) have strong psychometric properties, and have demonstrated research and clinical utility. The current study aimed to develop a short form (ALSSQOL-SF) suitable for limited clinic time and patient stamina.

METHODS: The ALSSQOL-SF was created using Item Response Theory and confirmatory factor analysis on 389 patients. A cross-validation sample of 162 patients assessed convergent, divergent, and construct validity of the ALSSQOL-SF compared to psychosocial and physical functioning measures.

RESULTS: The ALSSQOL-SF consisted of 20 items. Compared to the ALSSQOL-R, optimal precision was retained, and completion time was reduced from 15-25 minutes to 2-4 minutes. Psychometric properties for the ALSSQOL-SF and its subscales were strong.

DISCUSSION: The ALSSQOL-SF is a disease-specific global QOL instrument that has a short administration time suitable for clinical use, and provides clinically useful, valid information about persons with ALS. This article is protected by copyright. All rights reserved.

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Muscle & Nerve

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This article was published in Muscle & Nerve.

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