Effect of erythrocytes of androgens on 2,3-diphosphoglycerate in patients with chronic obstructive pulmonary disease
Because androgen therapy is known to increase 2,3-diphosphoglycerate in the erythrocytes of patients with chronic renal failure, the possibility that it might have a similar effect on patients with chronic obstructive pulmonary disease appeared worth investigating. Results of a small study appear promising, with improvement in stress tolerance and general well-being. Pulmonary function was not improved, and the severity of pulmonary disease was not affected, but further investigation of the treatment appears to be warranted.
Simelaro, John P.; Venditto, Michael; and Ghens, M., "Effect of erythrocytes of androgens on 2,3-diphosphoglycerate in patients with chronic obstructive pulmonary disease" (1980). PCOM Scholarly Papers. 1503.