Selective neurotoxic action of capsaicin on glomerular C-type terminals in rat substantia gelatinosa

Document Type

Article

Publication Date

1981

Abstract

This study demonstrates that capsaicin exerts a selective neurotoxic action to induce degeneration of glomerular C-type nerve terminals in adult rats. Since the C terminals may be essential components of the circuitryfor modulation of pain, it is suggested that capsaicin induced analgesia is the result of this neurotoxic action. © 1981.

Publication Title

Brain research

Volume

208

Issue

2

First Page

506

Last Page

510

Comments

This article was published in Brain research, Volume 208, Issue 2, Pages 506-510.

The published version is available at http://dx.doi.org/10.1016/0006-8993(81)90585-0.

Copyright © 1981 Elsevier.

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