Date of Award


Degree Type

Selective Evidence-Based Medicine Review

Degree Name

Master of Science in Health Sciences - Physician Assistant


Physician Assistant Studies

Department Chair

John Cavenagh, MBA, PhD, PA-C


Objective: The objective of this selective EBM is to determine whether or not resistance training is effective in improving mobility for patients with Parkinson’s disease.

Study Design: Review of four English language randomized control trials (RCT) published between 2012-2013.

Data Sources: Articles used were RCTs and published in peer reviewed journals and found using Pubmed, JAMA, and NCBI.

Outcomes Measured: Effectiveness was measured by comparing a sham, or non-resistance based exercise group, to a resistance based group. Improvement in mobility was measured using UPDRS-III scores.

Results: Patients with Parkinson’s have slow and weak movements which should be improved with resistance training. Corcos et al showed that resistance training improved UPDRS-III over a comparison group with a mean difference of 7.3 points (P

Outcome: Resistance training is likely to improve mobility in patients with Parkinson’s Disease when compared to control groups and with a minimal risk of harm.