Date of Award
Selective Evidence-Based Medicine Review
Master of Science in Health Sciences - Physician Assistant
Physician Assistant Studies
John Cavenagh, MBA, PhD, PA-C
Objective: The objective of this selective EBM review is to determine whether or not the use of yoga helps to improve fatigue in patients with Multiple Sclerosis (MS).
Study Design: Review of three randomized controlled trials (RCTs) published between 2004-current, all in the English language.
Data Sources: Three randomized controlled trials (RCTs), all of which evaluate the effectiveness of yoga compared to a control group that was asked not to change their exercise habits as they pertain to fatigue. All studies were found using PubMed and EBSCOhost.
Outcomes Measured: Each of the three articles analyzed the effects of yoga therapy on improving fatigue. The Fatigue Severity Scale (FFS), Modified Fatigue Impact Scale (MFIS), and Multi-dimensional Fatigue Inventory (MFI) were the questionnaires used to measure fatigue.
Results: One study found that yoga significantly reduced fatigue in MS patients. One study approached statistical significance in support for yoga as an effective therapy. One study was inconclusive.
Conclusions: Evidence is inconclusive. Future studies should focus on long-term effects of yoga and include subjects with more than minimal gait impairment.
Hessler, Melissa L., "Is Yoga Effective in Reducing Fatigue in Patients With Multiple Sclerosis?" (2015). PCOM Physician Assistant Studies Student Scholarship. 226.