Regeneration of uterine horn using porcine small intestine submucosa grafts in rabbits

Authors

Jon W. Taveau, Philadelphia College of Osteopathic Medicine
Michele Tartaglia, Philadelphia College of Osteopathic Medicine
Dana Buchanan, Philadelphia College of Osteopathic Medicine
Bret Smith, Philadelphia College of Osteopathic Medicine
George Koenig, Philadelphia College of Osteopathic Medicine
Kevin Thomfohrde, Philadelphia College of Osteopathic Medicine
Bruce Stouch, Philadelphia College of Osteopathic Medicine
Saul Jeck, Philadelphia College of Osteopathic MedicineFollow
Charlotte H. Greene, Philadelphia College of Osteopathic MedicineFollow

Document Type

Article

Publication Date

2004

Abstract

Tubal factor infertility may be reversed using porcine small-intestinal submucosa (SIS). The method uses as a model the New Zealand White rabbit uterine horn. In surgery, SIS grafts were prepared from porcine jejunuml the uterine horn segment was resected and a graft was placed, then the contralateral adnexa was resected. Fecundability was tested with natural mating. Three out of six rabbits became pregnant. Gross and microscopic examination confirmed regeneration of all tissue layers. Thus, this study determined that SIS facilitates successful regeneration of uterine horn morphology in a manner similiar to that observed in other tissues and species.

Publication Title

Journal of Investigative Surgery

Volume

17

First Page

81

Last Page

82

Comments

This article was published in Journal of Investigative Surgery, Volume 17, Pages 81-92.

Copyright © 2004 Taylor and Francis.

Recommended Citation

Taveau, Jon W.; Tartaglia, Michele; Buchanan, Dana; Smith, Bret; Koenig, George; Thomfohrde, Kevin; Stouch, Bruce; Jeck, Saul; and Greene, Charlotte H., "Regeneration of uterine horn using porcine small intestine submucosa grafts in rabbits" (2004). PCOM Scholarly Works. 999.
https://digitalcommons.pcom.edu/scholarly_papers/999