VEGF expression in forestomach cancer and precancerous lesions in mice and investigation of chemoprophylaxis trail

Authors

Qian Chen, Philadelphia College of Osteopathic MedicineFollow
X. Lian
W. Zheng
B. Zhou
X. Wu

Document Type

Article

Publication Date

2003

Abstract

Objective: To investigate intervention and mechanism of forestomach cancer and precancerous lesions in mice by Chanpi, Quanchong and Fengfang mixed liquid (CQF liquid). Methods: The model of forestomach cancer and precancerous lesions in mice was established by N-nitrososarcosine ethyl ester and sodium nitrite perfusing stomach; VEGF expressions in cancer-induced group (32 cases), the traditional Chinese medicine (20 cases) and blocked group (48 cases) were determined by ELPS. Results: Circled digit one The incidence of cancer and precancerous lesions was markedly higher in cancer-induced group than in blocked group; Circled digit two the positive rate and intensity of VEGF expression were significantly higher in cancer-induced group than in blocked group. Conclusion: CQF liquid can interrupt forestomach cancer and precancerous lesions in mice, and is related to VEGF expression. VEGF is a factor involved in forestomach cancer and precancerous lesions in mice.

Publication Title

Journal of Xi'an Jiaotong University (Medical Sciences)

Volume

24

Issue

5

First Page

474

Last Page

476

Comments

This article was published in Journal of Xi'an Jiaotong University (Medical Sciences), Volume 24, Issue 5, Pages 474-476.

Copyright © 2003 Xian Jiaotong University.

Recommended Citation

Chen, Qian; Lian, X.; Zheng, W.; Zhou, B.; and Wu, X., "VEGF expression in forestomach cancer and precancerous lesions in mice and investigation of chemoprophylaxis trail" (2003). PCOM Scholarly Works. 992.
https://digitalcommons.pcom.edu/scholarly_papers/992