Title

The Role of Micronutrients in the Response to Ambient Air Pollutants: Potential Mechanisms and Suggestions for Research Design

Document Type

Article

Publication Date

1-1-2017

Abstract

People living in regions of low socioeconomic status are thought to be prone to higher exposures to environmental pollutants, poor nutrition, and numerous preventable diseases and infections. Poverty correlates with pollution and malnutrition; however, limited studies examined their interrelationship. The well-studied, deleterious health effects attributed to environmental pollutants and poor nutrition may act in combination with produce more severe adverse health outcomes than any one factor alone. Deficiencies in specific nutrients render the body more susceptible to injury which may influence the pathways that serve as the mechanistic responses to ambient air pollutants. This review (1) explores specific micronutrients that are of global concern, (2) explains how these nutrients may impact the body's response to ambient air pollution, and (3) provides guidance on designing animal models of nutritional deficiency. It is likely that those individuals who reside in regions of high ambient air pollution are similarly malnourished. Therefore, it is important that research identifies specific nutrients of concern and their impact in identified regions of high ambient air pollution.

Publication Title

Journal of Toxicology and Environmental Health. Part B, Critical Reviews

Volume

20

Issue

1

First Page

38

Last Page

53

PubMed ID

28145849

Comments

This article was published in Journal of Toxicology and Environmental Health. Part B, Critical Reviews, Volume 20, Issue 1, Pages 38-53.

The published version is available at http://dx.doi.org/10.1080/10937404.2016.1261746.

Copyright © 2017.

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