Title

Use of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 (COX-2) inhibitors: Indications and complications

Document Type

Article

Publication Date

2002

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medications-both prescription and over the counter-in the United States. Gastrointestinal side effects from NSAIDs are responsible for significant patient morbidity and mortality as well as healthcare cost. With the development of cyclooxygenase-2 (COX-2) specific inhibitors, these serious adverse reactions have been significantly reduced without affecting therapeutic benefit; however, the need for careful monitoring of patients on therapy with traditional NSAIDs and COX-2 inhibitors continues. In this article, recent developments regarding COX-2 inhibitors and potential future uses of this class of drugs are also discussed.

Publication Title

Journal of the American Osteopathic Association

Volume

102

Issue

9

First Page

487

Last Page

489

Comments

This article was published in Journal of the American Osteopathic Association, Volume 102, Issue 9, Pages 487-489.

The published version is available at https://jaoa.org/article.aspx?articleid=2092657.

Copyright © 2002.

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