Potentiation of catecholamine inhibition of ganglionic transmission by Δ9-tetrahydrocannabinol

Authors

Frederick J. Goldstein, Philadelphia College of Osteopathic MedicineFollow
E. Vernot
H. K. Strahlendorf

Document Type

Article

Publication Date

1977

Abstract

The effect of Δ9-tetrahydrocannabinol upon exogenous catecholamine inhibition of synaptic transmission was evaluated in the rabbit superior cervical ganglion. Δ9-Tetrahydrocannabinol (7.5 and 15 μg/kg, i.v.) was without effect upon electrically evoked transmission, but potentiated norepinephrine-induced ganglionic inhibition. Epinephrine, but not dopamine, was similarly facilitated. © 1977.

Publication Title

Neuropharmacology

Volume

16

Issue

1

First Page

71

Last Page

72

Comments

This article was published in Journal of pharmaceutical sciences, Volume 59, Issue 3, Pages 425-426.

Recommended Citation

Goldstein, Frederick J.; Vernot, E.; and Strahlendorf, H. K., "Potentiation of catecholamine inhibition of ganglionic transmission by Δ9-tetrahydrocannabinol" (1977). PCOM Scholarly Works. 1325.
https://digitalcommons.pcom.edu/scholarly_papers/1325