Location

Philadelphia, PA

Start Date

8-5-2019 1:00 PM

End Date

8-5-2019 4:00 PM

Description

Objective: The aim of this study is to compare stage and mortality in colorectal cancer (CRC) patients above and below age 50. We hypothesize that patients under age 50 will be diagnosed at a higher stage and have a lower mortality rate. Reports show an increase in CRC diagnoses in younger patients, however, data on this patient population is limited and further investigation is required.

Methods: A 20-year review of electronic medical records was completed from 1997 to 2017 of all patients diagnosed with CRC. This data was aggregated and univariate analysis was performed.

Results: Of the 3188 patients diagnosed with CRC, 245 (7.7%) were below age 50 and 2943 (92.3%) were above age 50. Younger patients were more likely to be diagnosed at stage two or higher, 71.4% (165/231) compared to 56.5% (1589/2810) of those above age 50 (p

Discussion: We reject our null hypothesis. Younger patients under age 50 were diagnosed at higher stages, however, their 5 year mortality was lower than those diagnosed with CRC above age 50. Our data would support updated guidelines to initiate screening colonoscopies at age 45 instead of 50. Further investigations are required in this understudied population.

Embargo Period

5-24-2019

Comments

Presented by Sarah Martin.

Presented at the Keystone Chapter of the American College of Surgeons Annual Meeting.

COinS
 
May 8th, 1:00 PM May 8th, 4:00 PM

Colorectal Cancer in Patients Under Age 50: Staging and Mortality at a Single Institution

Philadelphia, PA

Objective: The aim of this study is to compare stage and mortality in colorectal cancer (CRC) patients above and below age 50. We hypothesize that patients under age 50 will be diagnosed at a higher stage and have a lower mortality rate. Reports show an increase in CRC diagnoses in younger patients, however, data on this patient population is limited and further investigation is required.

Methods: A 20-year review of electronic medical records was completed from 1997 to 2017 of all patients diagnosed with CRC. This data was aggregated and univariate analysis was performed.

Results: Of the 3188 patients diagnosed with CRC, 245 (7.7%) were below age 50 and 2943 (92.3%) were above age 50. Younger patients were more likely to be diagnosed at stage two or higher, 71.4% (165/231) compared to 56.5% (1589/2810) of those above age 50 (p

Discussion: We reject our null hypothesis. Younger patients under age 50 were diagnosed at higher stages, however, their 5 year mortality was lower than those diagnosed with CRC above age 50. Our data would support updated guidelines to initiate screening colonoscopies at age 45 instead of 50. Further investigations are required in this understudied population.