Use of Negative-Pressure Wound Therapy With Instillation and Dwell Time: An Overview

Document Type


Publication Date



The use of negative-pressure wound therapy (NPWT) has become an established therapy for wound management. There have been many advancements in the technology of NPWT including NPWT with instillation and dwell (NPWTi-d). NPWTi-d promotes wound healing by wound cleansing, irrigation, and nonexcisional debridement. NPWTi-d has been shown in comparative clinical studies to decrease the time to definitive wound healing and length of hospitalization. NPWTi-d-using a reticulated open-cell foam dressing with "through" holes (ROCF-CC)-has been postulated to facilitate solubilization, detachment, and elimination of infectious materials, such as slough and thick exudate, before or after operative debridement, and in cases where surgical debridement is not an option. The authors provide an overview on the use of NPWTi-d by reviewing the components of the system, proposed mechanism of action, clinical outcomes, and current consensus guidelines for its utilization.


This article was published in Plastic and Reconstructive Surgery.

The published version is available at https://doi.org/10.1097/prs.0000000000007607.

Copyright © 2020 American Society of Plastic Surgeons.

Publication Title

Plastic and Reconstructive Surgery

PubMed ID


This document is currently not available here.