Date of Award
Selective Evidence-Based Medicine Review
Master of Science in Health Sciences - Physician Assistant
Physician Assistant Studies
OBJECTIVE: The objective of this systematic review is to determine whether or not bimatoprost 0.03% improves satisfaction in patients at least 12 years old with eyelash hypotrichosis.
STUDY DESIGN: Systematic review of three multicenter, double-masked, randomized, parallel group studies, all published in English between 2015 and 2016.
DATA SOURCES: All three studies used in this review were researched via PubMed and were published in peer-reviewed journals.
OUTCOMES MEASURED: Patient satisfaction was measured using the Eyelash Satisfaction Questionnaire (ESQ) in all three studies.
RESULTS: Wirta et al. (J Clin Aesthet Dermatol. 2015;8:11–20.) found a statistically significant relationship between bimatoprost 0.03% and satisfaction with a p=0.004. Borchert et al. (Clin Ophthalmol. 2016;10:419-29. doi:10.2147/OPTH.S89561) did not indicate a p-value but 78.2% of subjects treated with bimatoprost 0.03% and 65% of subjects in the control were found to have an increase in satisfaction of eyelash growth at the end of the study. The study conducted by Glaser et al. (Br J Dermatol. 2015;172(5):1384-94.) did not find a statistically significant relationship between bimatoprost 0.03% and satisfaction with p=0.25.
CONCLUSIONS: The results of these studies show that the objective question remains inconclusive in regard to increasing patient satisfaction after the use of bimatoprost 0.03% as only one out of the three studies showed a statistically significant relationship. Further studies should be conducted with researchers not employed by the pharmaceutical company who manufactures the product.
Boyer, Crystal, "Is Bimatoprost Effective In Increasing Satisfaction In Patients At Least 12 Years Old With Eyelash Hypotrichosis?" (2020). PCOM Physician Assistant Studies Student Scholarship. 511.