Date of Award


Degree Type

Selective Evidence-Based Medicine Review

Degree Name

Master of Science in Health Sciences - Physician Assistant


Physician Assistant Studies


OBJECTIVE: The objective of this selective EBM review is to determine whether or not resistance training exercises help improve symptoms of depression and/or depression scores.

STUDY DESIGN: Review of three randomized control trials (RTCs), all published from 2009 to present and all written in the English language.

DATA SOURCES: Data sources included peer reviewed articles that were published on PubMed and were selected based on their relevance to the research question and patient outcomes measured.

OUTCOME MEASURED: The clinical outcome of depression symptom improvement with resistance training exercises was measured in these studies using the Center for Epidemiological Studies Depression scale (CES-D) and the Cornell Scale for Depression in Dementia (CSDD). RESULTS: The study by Chen et al. showed a significant decrease in CSDD scores (p=0.009) between the resistance training (RT) and control group. The studies by Sims et al. and LeCheminant et al. showed no significant difference (P>0.05) in depression scores between the intervention and control groups.

CONCLUSIONS: Based on the results of the three studies, it appears that RT does not significantly improvement depression symptoms, however further research is needed to determine if there is significant improvement compared to other treatment options.