Date of Award
Selective Evidence-Based Medicine Review
Master of Science in Health Sciences - Physician Assistant
Physician Assistant Studies
John Cavenagh, MBA, PhD, PA-C
Objective: The objective of this selective EBM review is to determine whether or not weight loss is an effective treatment of pain symptoms related to knee joint osteoarthritis in obese adults.
Study Design: Systematic review of 2 randomized-controlled trials and 1 cohort study. All three articles were published in English between 2011-2015.
Data Sources: Two randomized, un-blinded, controlled studies and one cohort found using Pubmed.
Outcomes Measured: Each study evaluated change in pain symptoms related to knee osteoarthritis in obese adults as compared to weight loss.
Results: Studies showed that weight loss lead to a decrease in osteoarthritis knee pain.
Conclusions: These studied showed that weight loss in obese adults is an effective treatment for knee pain due to osteoarthritis. All studies showed a decrease in pain symptoms with weight reduction, regardless of the type of weight loss intervention.
Sokol, Samantha, "Is Weight Loss an Effective Treatment of Pain Symptoms Related to Knee Joint Osteoarthritis in Obese Adults?" (2017). PCOM Physician Assistant Studies Student Scholarship. 417.