Date of Award
Selective Evidence-Based Medicine Review
Master of Science in Health Sciences - Physician Assistant
Physician Assistant Studies
John Cavenagh, MBA, PhD, PA-C
OBJECTIVE: The objective of this selective EBM review is to determine whether or not physical activity, when combined with androgen deprivation therapy, yields a better quality of life in survivors of prostate cancer.
STUDY DESIGN: Three randomized, controlled trials (RCTs) were found using the PubMed and Cochrane databases. The studies compared regular physical activity in men undergoing androgen deprivation therapy for prostate cancer.
OUTCOMES MEASURED: The outcomes measured were self-reported quality of life surveys at different time intervals.
RESULTS: Two out of the three studies demonstrated statistically significant improvement in reported quality of life during the exercise programs. The third study did not find significant increases in quality of life.
CONCLUSIONS: Based off of the data collected, physical activity seems to be safe and effective in improving quality of life in men undergoing androgen deprivation therapy for prostate cancer.
Ridolfi, Nicholas J., "Does Physical Activity, When Combined With Androgen Deprivation Therapy, Yield a Better Quality of Life in Prostate Cancer Survivors?" (2016). PCOM Physician Assistant Studies Student Scholarship. 305.