The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.

The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.

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Submissions from 2014

Evidence of Declining Empathy in Third Year Osteopathic Medical Students, Hilary M. Caruso and Bettina Bernstein

Marked improvement of vulvovaginitis of unknown origin in a pediatric patient - Case report, Jerome H. Check and Rachael A. Cohen

Severe Headaches from Intracranial Hypertension (Pseudotumor Cerebri) Abrogated by Treatment with Dextroamphetamine Sulfate, Jerome H. Check and Rachael A. Cohen

Sympathomimetic Amine Therapy Found Effective for Treatment of Refractory Chronic Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy), Jerome H. Check and Rachael A. Cohen

The Triad of Luteal Phase Ocular Migraines, Interstitial Cystitis, and Dyspareunia as a Result of Sympathetic Nervous System Hypofunction, Jerome H. Check and Rachael A. Cohen

Failure to Improve a Thin Endometrium in the Late Proliferative Phase with Uterine Infusion of Granulocyte-Colony Stimulating Factor, Jerome H. Check, Rachael A. Cohen, and J. K. Choe

Methamphetamine abuse usurps hippocampal neural network operations undergirding memory consolidation, Sanika Chirwa, Adwoa Aduonum, and Habibeh Khoshbouei

The Impacts of Comparative Anatomy of Electric Rays (Batoidea: Torpediniformes) on their Systematic Hypotheses, Kerin M. Claeson

A Revision of the Upper Cretaceous Lepidosirenid Lungfishes from the Quseir Formation, Western Desert, Central Egypt, Kerin M. Claeson, Hesham M. Sallam, Patrick M. O'Connor, and Joseph J. W. Sertich

Response to letter to the editor: A practical guide to concentrated insulin for pharmacists, Jennifer Clements and Jennifer Andres

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Predictors and moderators of treatment response in childhood anxiety disorders: Results from the CAMS trial, Scott N. Compton, Tara S. Peris, Daniel Almirall, Boris Birmaher, Joel Sherrill, Phillip C. Kendall, John S. March, Elizabeth A. Gosch, Golda S. Ginsburg, and et al.

Somatic Complaints in Anxious Youth, Sarah A. Crawley, Nicole E. Caporino, Boris Birmaher, Golda Ginsburg, John Piacentini, Anne Marie Albano, Joel Sherrill, Dara Sakolsky, Scott N. Compton, Moira Rynn, James McCracken, Elizabeth Gosch, Courtney Pierce Keeton, John March, John T. Walkup, and Philip C. Kendall

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Phenotype of Transgenic Mice Carrying a Very Low Copy Number of the Mutant Human G93A Superoxide Dismutase-1 Gene Associated with Amyotrophic Lateral Sclerosis, Jeffrey S. Deitch, Guillermo M. Alexander, Andrew Bensinger, Steven Yang, Juliann T. Jiang, and Terry D. Heiman-Patterson

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Tbx5 is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis., Nata Y Diman, Gabriel Brooks, Boudewijn P Kruithof, Olivier Elemento, Jonathan G Seidman, Christine Seidman, Craig T Basson, and Cathy J. Hatcher

Incorporation of pazopanib in maintenance therapy of ovarian cancer, A. DuBois, A. Floquet, J. Kim, J. Rau, J. Del Campo, M. Friedlander, S. Pignata, K. Fujiwara, Rocco J. Crescenzo, and et al.

The Survey of Treatment Entry Pressures (STEP): identifying client's reasons for entering substance abuse treatment, K. Dugosh, David Festinger, K. Lynch, and D. Marlowe

Developing an index to measure the voluntariness of consent to research, K. Dugosh, David Festinger, D. Marlowe, and N. Clements

Contingency management for cocaine treatment: Cash vs. vouchers, David Festinger, K. Dugosh, K. Kirby, and B. Seymour

Achieving new levels of recall in consent to research by combining remedial and motivational techniques, David Festinger, K. Dugosh, D. Marlowe, and N. Clements

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Malnutrition and Depression, Katherine E. Galluzzi, Barry Rovner, and Stephen Di Sabatino

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Myo/Nog Cells: Targets for Preventing the Accumulation of Skeletal Muscle-Like Cells in the Human Lens, Jacquelyn Gerhart, M. Greenbaum, V. Scheinfeld, P. Fitzgerald, M. Crawford, Arturo Bravo Nuevo, M. Pitts, and Mindy George-Weinstein

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Immediate Return to Ambulation and Improved Functional Capacity for Rehabilition in Complex Regional Pain Syndrome following Early Implantation of a Spinal Cord Stimulation System, Brandon Jesse Goff, Jeremy Wingseng Naber, John Patrick McCallin, Edward Michael Lopez, Kevin Brant Guthmiller, Karl Alan Lautenschlager, Tristan Toll Lai, Dean Harry Hommer, and Gonzalez Raul Marin

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Targeting the immune system to treat hypertension: Where are we?, Jennifer L. Gooch and Avadhesh C. Sharma

Targeting the immune system to treat hypertension: Where are we?, Jennifer Gooch and Avadhesh C. Sharma

Gray Zone: Why a Delayed Acceptance of Osteopathic Medicine Persists in the International Community., Rachel L Gougian and Murray R. Berkowitz

To the point: Obstetrics and gynecology global health experiences for medical students, B. S. Hampton, A. W. Chuang, J. F. Abbott, S. D. Beury-Joyner, A. J. Cullimore, J. L. Dalrymple, D. A. Forstein, N. A. Hueppchen, Joseph M. Kaczmarczyk, and S. Page-Ramsey

G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease., Guichun Han and Richard E. White

Keyboard data entry use among osteopathic medical students and residents, Julia M. Helstrom, Erik Langenau, Jeanne M. Sandella, and Beth L. Mote

Hypoxia and free radicals: Role in tumor progression and the use of engineering-based platforms to address these relationships, Abigail Hielscher and S. Gerecht

Detection of Anorexia Nervosa in Primary Care: Effects of Patient Ethnicity, History of Mental Illness, Physician Gender, and Years of Experience., Ashley Higgins, Stacey C. Cahn, Robert A. DiTomasso, and Harry J. Morris

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A capstone course with a comprehensive and integrated review of the pharmacy curriculum and student assessment as a preparation for advanced pharmacy practice experiences, Adina C. Hirsch and Harish S. Parihar

Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation., P. E. Hooijman, M. A. Paul, G. J. Stienen, A. Beishuizen, H. W. Van Hees, S. Singhal, M. Bashir, M. T. Budak, Robert J. Barsotti, and et.al

Unaffected Contractility of Diaphragm Muscle Fibers in Humans on Mechanical Ventilation., Pleuni E Hooijman, Marinus A Paul, Ger J M Stienen, Albertus Beishuizen, Hieronymus W H Van Hees, Sunil Singhal, Muhammad Bashir, Murat T. Budak, Jacqueline Morgen, Robert J. Barsotti, Sanford Levine, and Coen A C Ottenheijm

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Child involvement, alliance, and therapist flexibility: Process variables in cognitive-behavioural therapy for anxiety disorders in childhood, Jennifer L. Hudson, Philip C. Kendall, Brian C. Chu, Elizabeth A. Gosch, Erin Martin, Alan Taylor, and Ashleigh Knight

miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export, M. B. Hudson, M. E. Woodworth-Hobbs, B. Zheng, J. A. Rahnert, M. A. Blount, Jennifer L. Gooch, C. D. Searles, and S. Russ Price

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Web-Based Objective Structured Clinical Examination with Remote Standardized Patients and Skype: Resident Experience, Erik E. Langenau, Elizabeth Kachur, and Dot Horber

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Introducing Blended Learning to Medical Students in a Clinical Training Environment, Erik Langenau and Douglas Koch

Somatic dysfunction and use of osteopathic manual treatment techniques during ambulatory medical care visits: a CONCORD-PRBN study, John C. Licciardone; Cathleen M. Kearns; Hollis H, King; Michael A. Seffinger; W. Thomas Crow; Peter Zajac; William H. Devine; Reem Y. Abu_Sbaih; Stephen J. Miller; and Murray R. Berkowitz

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Chlamydia pneumoniae Infection of Monocytes in vitro Stimulates Innate and Adaptive Immune Responses Relevant to those in Alzheimer's Disease., Charles Lim, Christine Hammond, Susan Hingley, and Brian J. Balin PhD

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Detection of Bacterial Antigens and Alzheimer's Disease-like Pathology in the Central Nervous System of BALB/c Mice Following Intranasal Infection with a Laboratory Isolate of Chlamydia pneumoniae, C. Scott Little PhD, Timothy A. Joyce, Christine Hammond, Hazem Matta, David Cahn, Denah Appelt, and Brian J. Balin PhD

Use of a Small Intestine Submucosa Extracellular Matrix Patch in Repeated Carotid Endarterectomy, Nicholas J. Madden, Douglas A. Troutman, and Arthur J. DeMarsico

Pediatric Arytenoid Dislocation: Diagnosis and Treatment., Andrew S. Mallon, Joel E. Portnoy, Tré Landrum, and Robert T. Sataloff

Pediatric Shopping-Cart-Related Injuries Treated in US Emergency Departments, 1990-2011, Keith Martin, Thiphalak Chounthirath, Huiyun Xiang, and Gary A. Smith

Acute and Chronic Compartment Syndromes: Know When to Act Fast, Nancy McLaughlin, Hank Heard, and Steven Kelham

Staff Perspectives on Juvenile Drug Court Operations: A Multi-Site Qualitative Study, A. Mericle, S. Belenko, David Festinger, J. Fairfax-Colombo, and M. McCart

Acute Exposure to High-Fat Diets Increases Hepatic Expression of Genes Related to Cell Repair and Remodeling in Female Rats, Colette N. Miller, Heidi P. Morton, Paula T. Cooney, Tricia G. Winters, Keshia R. Ramseur, Srujana Rayalam, Mary Anne Della-Fera, Clifton A. Baile, and Lynda M. Brown

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A Combined Therapeutic Regimen of Buspirone and Environmental Enrichment is more Efficacrious than Either Alone in Enhancing Spatial Learning in Brain-Injured Rats, Christina M. Monaco, Kory M. Gebhardt, Sarah M. Chlebowski, Kaitlyn E. Shaw, and Jeffrey P. Cheng

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Chewing Through the Miocene: An Examination of the Feeding Musculature in the Ground Sloth Hapalops from South America (Mammalia: Pilosa), Virginia L Naples and Robert McAfee

Molecular Functions and Significance of the MTA Family in Hormone-Independent Cancer, Zhifeng Ning, Jinfeng Gan, Chaoying Chen, Dianzheng Zhang, and Hao Zhang

Cardiac catheterization: A review for pharmacists, Mebanga Ojong, Chad Weinhold, Afeez Salako, and Jennifer Andres

The Primacy of IQ Subtest Analysis to Understand Reading Performance for Culturally Diverse Groups, Samuel O. Ortiz, Harriet N. Johnson, Gabrielle Wilson, Stella F. Francis, and Yuma Iannotti Tomes

Overview of Adult Outpatient Cancer Pain Management, Sonia Patel

Safe Handling of Chemotherapy for Pharmacists, Sonia Patel

Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Youjuan Pei, Aiming Wang, Yong Zhao, Ling Yan, Min Li, Richard E. White, and Gui Chun Han

Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism, Y. Pei, A. Wang, Y. Zhao, L. Yan, M. Li, Richard E. White, and G. C. Han

Trajectories of Change in Youth Anxiety During Cognitive-Behavior Therapy., Tara S Peris, Scott N Compton, Philip C Kendall, Boris Birmaher, Joel Sherrill, John March, Elizabeth Gosch, Golda Ginsburg, Moira Rynn, James T McCracken, Courtney P Keeton, Dara Sakolsky, Cynthia Suveg, Sasha Aschenbrand, Daniel Almirall, Satish Iyengar, John T Walkup, Anne Marie Albano, and John Piacentini

Cognitive-Behavioral Therapy for Anxious Youth with a Disability: a Case Study, Jeremy S. Peterman, Alexandra L. Hoff, Elizabeth Gosch, and Philip C. Kendall

Thyroglossal Duct Papillary Carcinoma in a 15-year old Female and Review of Pediatric Cases of thyroglossal duct carcinoma., Michael S Pfeiffer, Grace H Kim, and Miguel Krishnan

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24- and 36-Week Outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS), John Piacentini, Shannon Bennett, Scott N. Compton, Phillip C. Kendall, Boris Birmaher, Anne Marie Albano, John March, Joel Sherrill, Dara Sakolsky, Golda Ginsburg, Moira Rynn, R. Lindsey Bergman, Elizabeth Gosch, Bruce Waslick, Satish Iyengar, James McCracken, and John T. Walkup

Efficacy of Super High Dose Proton Pump Inhibitor Administration in Refractory Laryngopharyngeal Reflux: A Pilot Study, Joel E. Portnoy, Naomi D. Gregory, Claudia E. Cerulli, Mary J. Hawkshaw, Deborah Lurie, Philip O. Katz, and Robert T. Sataloff

Inhibition of Long Chain Fatty Ccyl-CoA Synthetase (ACSL) and Ischemia Reperfusion Injury, Allan M. Prior, Man Zhang, Nina Blakeman, Palika Datta, Hung Pham, Qian Chen, Lindon H. Young, Margaret T. Weis, and Duy H. Hua

Bilateral Vocal Fold Immobility, Kelli A. Quercetti and Amanda Hu

Predicting Anxiety Diagnoses and Severity with the CBCL-A: Improvement Relative to Other CBCL Scales?, Kendra L. Read, Cara A. Settipani, Jeremy Peterman, Philip C. Kendall, Scott Compton, John Piacentini, James McCracken, Linsey Bergman, Elizabeth A. Gosch, and et al.

Use of Rapid-Acting Insulin Analogs During Pregnancy, Sara Wilson Reece, Alexander Kanopka, and Iana Mervin

Metformin in gestational diabetes mellitus, Sara Wilson Reece, Harish S. Parihar, and Christina LoBello

The Beauty Bias: the Injustice of Appearance in Life and Law, Deborah L. Rhode

Perioperative Nonopioid Agents for Pain Control in Spinal Surgery., Anna Rivkin and Mark Rivkin

Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom

Novel free-hand T1 pedicle screw method: Review of 44 consecutive cases, Mark A. Rivkin, J. F. Okun, and Steven S. Yocom

Thoracolumbar instrumentation with CT-guided navigation (O-arm) in 270 consecutive patients: Accuracy rates and lessons learned, Mark A. Rivkin and Steven S. Yocom

Thoracolumbar instrumentation with CT-guided navigation (O-arm) in 270 consecutive patients: Accuracy rates and lessons learned, Mark A. Rivkin and Steven S. Yocom

Stratigraphy and Vertebrate Paleoecology of Upper Cretaceous? Lowest Paleogene Strata on Vega Island, Antarctica, Eric M. Roberts, Matthew C. Lamanna, Julia A. Clarke, Jin Meng, Eric Gorscak, Joseph J. W. Sertich, Patrick M. O'Connor, Kerin M. Claeson, and Ross D. E. MacPhee

Pubic Bone Osteomyelitis after Salvage High-Intensity Focused Ultrasound for Prostate Cancer, Christopher Robison, R. A. Gor, and M. J. Metro

Impact of celebrity endorsements in disease-specific direct-to-consumer (DTC) advertisements, Brent L. Rollins and Nilesh Bhutada

A Pharmacy Business Management Simulation Exercise as a Practical Application of Business Management Material and Principles, Brent L. Rollins, Rahul Gunturi, and Donald Sullivan

Direct-to-Consumer Advertising of Predictive Genetic Tests: A Health Belief Model Based Examination of Consumer Response., Brent L. Rollins, Shravanan Ramakrishnan, and Matthew Perri

Measuring Community Participation of Adults with Psychiatric Disabilities: Reliability of Two Modes of Data Collection., Mark S. Salzer, Eugene Brusilovskiy, Janet Prvu-Bettger, and Petra Kottsieper

Patterns of Misrepresentation of Clinical Findings on Patient Notes during the COMLEX-USA Level 2-PE, Jeanne M. Sandella, Larissa A. Smith, Laurie A. Gallagher, and Erik E. Langenau

Use of Therapeutic Hypothermia in Cocaine-Induced Cardiac Arrest: Further Evidence, Dane Scantling, Emily Klonoski, and Dominic J. Valentino

Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK-LGL leukaemia, Xiaoshen Sun, Zainul S. Hasanali, Allshine Chen, Dianzheng Zhang, Zin Liu, Hong Gang Wang, David J. Feith, Thomas P. Loughran Jr., and Kailin Xu

Vorapaxar: A Novel Antiplatelet Agent, Stephen Thompson, Carly Duncan, and Jennifer Andres

Cytoprotection of human endothelial cells against oxidative stress by 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im): Application of systems biology to understand the mechanism of action, Xinyu Wang, James A. Bynum, Solomon Stavchansky, and Phillip D. Bowman

Androgen therapy in women, Julie M. Wickman, Ashley Groves, Lauren Wiggins, and Nishman Patel

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EgoNet: Identification of human disease ego-network modules, Rendong Yang, Yun Bai, Zhaohui Qin, and Tianwei Yu

A Research Primer, Part 2: Guidelines for Developing a Research Project, David P. Yens, Grace D. Brannan, and Jane Z. Dumsha

Steroid Receptor Coactivator-3 Regulates Glucose Metabolism in Bladder Cancer Cells through Coactivation of Hypoxia Inducible Factor 1α, Wei Zhao, Cunjie Chang, Yangyan Cui, Xiaozhi Zhao, Jun Yang, Lan Shen, Ji Zhou, Zhibo Hou, Zhen Zhang, Changxiao Ye, Donald Hasenmayer, Robert Perkins, Xiaojing Huang, Xin Yao, Like Yu, Ruimin Huang, Dianzheng Zhang, Hongqian Guo, and Jun Yan

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Alternative splicing in the variable domain of CaMKIIβ affects the level of F-actin association in developing neurons., Jun Zheng, Lori R. Hardy, Chengshi Xu, Jing Kuang, and Weijing Liao

Submissions from 2013

Biomaterials, Christopher S. Adams

Gallbladder disease: Pathophysiology, diagnosis, and treatment, S. Afamefuna and Shari N. Allen

Treatment of depression in patients on anticoagulation therapy: Antidepressant-warfarin drug interactions, Shari N. Allen, Samuel John, Jennifer Shannon, and Jenna Ferrara

Movie Review: My left foot, Shari N. Allen and Mebanga Ojong

Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer, A. J. Armstrong, M. Haggman, W. M. Stadler, J. R. Gingrich, V. Assikiss, J. Polikoff, J. E. Damber, Laurence Belkoff, A. Nordle, and G. Forsberg

Basis for resveratrol's potential prevention and treatment of obesity osteoporosis, Clifton A. Baile, Mary Anne Della-Fera, and Srujana Rayalam

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Analysis of autophagy and inflammasome regulation in neuronal cells and monocytes infected with Chlamydia pneumoniae: Implications for Alzheimer’s disease, Brian J. Balin, Christine J. Hammond, Juliana Zoga, Ahmad B. Cader, Annette K. Slutter, Jonathan M. Anzman, Ian Kohler, Susan T. Hingley, and Denah M. Appelt

A Comparative Study of Cervical Hysteresis Characteristics after Various Osteopathic Manipulative Treatment (OMT) Modalities, Precious Barnes, Francisco Laboy, Lauren Noto-Bell, Veronica Ferencz MBA, Jeffrey A. Nelson, and Michael L. Kuchera

An open-label, long-term evaluation of the safety, efficacy and tolerability of avanafil in male patients with mild to severe erectile dysfunction, Laurence Belkoff, A. McCullough, I. Goldstein, L. Jones, C. H. Bowden, K. Didonato, B. Trask, and W. W. Day

Assessing impact of not attending lectures on osteopathic medical student performance: Brief survey of the literature and proposed future research, Murray R. Berkowitz

High-Level Specification of a Proposed Information Architecture for Support of a Bioterrorism Early-Warning System, Murray R. Berkowitz

New graduate medical education opportunities found - and lost, Murray R. Berkowitz

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Public Health Considerations of Launching Nuclear Waste to the Sun, Murray R. Berkowitz