The Philadelphia College of Osteopathic Medicine has a rich history of research, scholarship and publication, encompassing the case reports and reviews in the early Digests, the more formally presented articles in the College of Osteopathy's first research journal, Osteopathic Medicine, and current publications in some of the medical and pharmacology fields' leading peer-reviewed journals.

The PCOM Scholarly Papers repository is an archive for pre-publication drafts or final versions of research and editorial articles, abstracts, posters, and unpublished work by faculty and scientists at PCOM's Philadelphia and Georgia campuses.

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Submissions from 2015

Progression-free survival by local investigator versus independent central review: Comparative analysis of the AGO-OVAR16 Trial, A. Floquet, I. Vergote, N. Colombo, B. Fiane, B. J. Monk, A. Reinthaller, P. Calvert, T. Herzog, Rocco J. Crescenzo, and et al.

Considerations in the Selection of Antihyperglycemic Therapy for Older Patients With Type 2 Diabetes Mellitus: A Focus on Newer Therapies, Jeffrey Freeman

Considerations in the Selection of Antihyperglycemic Therapy for Older Patients With Type 2 Diabetes Mellitus: A Focus on Newer Therapies, Jeffrey Freeman

Compliance with recommendations made in a multidisciplinary ALS clinic., Timothy Fullam, Helen E Stephens, Stephanie H. Felgoise, Jacqueline K Blessinger, Susan Walsh, and Zachary Simmons

The Patient with Otitis Media, David B. Fuller

The Triune Nature of Humanity: Body, Mind, and Spirit, David B. Fuller

Jackfruit (Artocarpus heteophyllus) seed extract exhibits fibrino(geno)lytic activity, Sowmyashree Gangaraju, Bhagyalakshmi Manjappa, Girish Kesturu Subbaiah, Kemparaju Kempaiah, Rangaiah Shashidharamurthy, Jane Hoover Plow, Sebastin Santhosh Martin, Manohar Shindhe, and Devaraja Sannaningaiah

Hepatocyte Culture in Autologous Decellularized Spleen Matrix, Rui Gao, Wanquan Wu, Junxi Xiang, Yi Lu, Xinglong Zheng, Qian Chen, Haohua Wang, Bo Wang, Zhengwen Liu, and Feng Ma

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Motivational Interviewing is a Promising Framework for Collaboration in the Patient-Centered Medical Home, Scott Glassman

Orthopedic uses of stem cell therapy, Whitney B. Greco and Nancy McClaughlin

Neurologic diseases: the tragedy and the hope., Paula M. Gregory

Prospective Biomarker Analysis of the Randomized CHER-LOB Study Evaluating the Dual Anti-HER2 Treatment With Trastuzumab and Lapatinib Plus Chemotherapy as Neoadjuvant Therapy for HER2-Positive Breast Cancer., Valentina Guarneri, Maria Vittoria Dieci, Antonio Frassoldati, Antonino Maiorana, Guido Ficarra, Stefania Bettelli, Enrico Tagliafico, Silvio Bicciato, Daniele Giulio Generali, Katia Cagossi, Giancarlo Bisagni, Samanta Sarti, Antonino Musolino, Catherine Ellis, Rocco J. Crescenzo, and PierFranco Conte

Diagnosis of Migraines and Migraine Variants, Tomia P. Harmon

Developmental Regulation of Epicardial Cell Adhesion and Coronary Vasculogenesis, Cathy J. Hatcher, Brendan Tanner, Dina Abdurahman, Kolby Nelson, William Laidlaw, and Grzegorz Gorski

Abstract 87: Targeting androgen receptor acetylation as a treatment for castrate-resistant prostate cancer, Erin Heine, Diane E. Merry, Scott Dehm, Karen E. Knudsen, and Heather L. Montie

Efficacy of Avanafil 15 Minutes after Dosing in Men with Erectile Dysfunction: A Randomized, Double-Blind, Placebo Controlled Study, W. J. Hellstrom, J. Kaminetsky, Laurence Belkoff, I. Goldstein, J. P. Tursi, J. Uly, C. A. Peterson, C. H. Bowden, and W. W. Day

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer., David T Hoang, Lei Gu, Zhiyong Liao, Feng Shen, Pooja G Talati, Mateusz Koptyra, Shyh-Han Tan, Elyse Ellsworth, Shilpa Gupta, Heather L. Montie, Ayush Dagvadorj, Saija Savolainen, Benjamin Leiby, Tuomas Mirtti, Diane E Merry, and Marja T Nevalainen

Office Evaluation of Dizziness, James D. Hogue

The Mechanisms of Genetically Modified Vaccinia Viruses for the Treatment of Cancer, Artrish Jefferson, Valerie E. Cadet, and Abigail Hielscher

Antifactor Xa Monitoring in Patients on IV Unfractionated Heparin, Samuel N. John, Dusty L. Lisi, Nathan Greenfield, and Mary Littleton George

Low-Level Laser Therapy: An Alternative Treatment for Capsular Contraction, Jason D. Johnson, Paul M. Glat, and William L. Scarlett

Mediators of Change in the Child/Adolescent Anxiety Multimodal Treatment Study, Phillip C. Kendall, Colleen M. Cummings, Marianne A. Villa, Martina K. Narayanan, Kimberli Treadwell, Boris Birmaher, Scott Compton, John Piacentini, Elizabeth Gosch, and et al.

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Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus, Lawrence Charles Kenyon, Kaushiki Biswas, Kenneth Shindler, Manasi Nabar, Marjorie Stout, Susan T. Hingley, Judith B. Grinspan, and Jayasri Das Sarma

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Nutri One-on-One: The Assessment and Evaluation of a Brief One-on-One Nutritional Coaching in Patients Affected by Metabolic Syndrome, Jennifer King, Jeffrey E. Harris, David Kuo, and Farzaneh Daghigh

Reversal of novel oral anticoagulants, Winnie Lee, Deepa V. Patel, and Dusty L. Lisi

Protein Kinase C Beta II (PKC ßII) Peptide Inhibitor Exerts Cardioprotective Effects in Myocardial Ischemia/Reperfusion Injury, Christina Lipscombe, Israel Benjamin, Devon Stutzman, Amelie Bottex, Chinyere Ebo, William Chau, Harsh Patel, Qian Chen, Cathy Hatcher, Robert Barsotti, and Lindon Young

Celiac Artery Stent Placement for Coronary Ischemia, Nicholas J. Madden, Carmen Piccolo, Chittur Mohan, Ali Khoobehi, and Richard Sohn

A Flipped Classroom Approach to Teaching Lab-Based Techniques Leads to Greater Learning Gains, Melinda Maris

Pilot testing of an online training for criminal justice professionals on medication-assisted treatment, J. Matjekowski, K. Dugosh, N. Clements, and David Festinger

Assessing the Quality of Parent-Teacher Relationships for Students with ADHD, Jennifer A. Mautone, Enitan Marcelle, Katy E. Tresco, and Thomas J. Power

A dietary phytochemical blend prevents liver damage associated with adipose tissue mobilization in ovariectomized rats., Colette N Miller, Jeong-Yeh Yang, Tucker Avra, Suresh Ambati, Mary Anne Della-Fera, Srujana Rayalam, and Clifton A Baile

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Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes., Colette N Miller, Jeong-Yeh Yang, Emily England, Amelia Yin, Clifton A Baile, and Srujana Rayalam

Comparing the effectiveness of TAT and Myristoylation of gp91ds on Leukocyte Superoxide (SO) Release, Harsh Patel, Kyle Bartol, Amelie Bottex, Ryan Remarcke, William Chau, Sydney Walker, Qian Chen, Robert Barsotti, and Lindon Young

Lung Cancer Overview: Focus on Newer Therapies, Sonia Patel

Opioid Overdose Rescue Kits, Sonia Patel

Osteopathic manipulative treatment for an unusual presentation of fibromyalgia: A case report demonstrating the effectiveness of disease guidelines, Lauren Paul and Murray R. Berkowitz

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MeDiA: Mean Distance Association and Its Applications in Nonlinear Gene Set Analysis., Hesen Peng, Junjie Ma, Yun Bai, Jianwei Lu, and Tianwei Yu

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Learn About PCOM's Plastination Process, Philadelphia College of Osteopathic Medicine and Kerin M. Claeson

Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release, P. B. Radwanski, L. Brunello, R. Veeraraghavan, H. T. Ho, Q. Lou, M. A. Makara, A. E. Belevych, Mircea Anghelescu, and et al.

Management of Complications After Revision Shoulder Arthroplasty, Hithem Rahmi and Andrew Jawa

Consumer use of social media for health care and drug information: An exploratory study, Brent Rollins, Nilesh Bhutada, C. Crawford, and A. Hvizdos

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Milking the Information: Resources on Herbal Lactation Aids, Erica Rosalle

Transradial Peripheral Arterial Procedures, Kintur Sanghvi and John Coppola

MicroRNA-181a, a potential diagnosis marker, alleviates acute graft versus host disease by regulating IFN-γ production., Wei Sang, Cong Zhang, Dianzheng Zhang, Ying Wang, Cai Sun, Mingshan Niu, Xiaoshen Sun, Cui Zhou, Lingyu Zeng, Bin Pan, Wei Chen, Dongmei Yan, Feng Zhu, Qingyun Wu, Jiang Cao, Kai Zhao, Chong Chen, Zhenyu Li, Depeng Li, Thomas P Loughran, and Kailin Xu

Addiction Severity Index Scores and Urine Drug Screens at Baseline as Predictors of Graduation From Drug Court, S. Shah, D. DiMatteo, M. Keesler, J. Davis, K. Heilbrun, and David Festinger

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Clinically Significant Drug Interactions Associated With HIV Medications [CE Module], Kinjal Sidhpura

Osteopathic approach to chronic constipation in Prader-Willi Syndrome: A case report, Lauren Smith and Murray Berkowitz

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Glanzmann's thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options, Tia Solh, Ashley Botsford, and Melhem Solh

Improving the psychiatric interview in the physician assistant behavioral medicine curriculum: A novel approach, Tia Solh, Daniel Paulson, and Dixie Pennington

Recessive dystrophic epidermolysis bullosa: A review of disease pathogenesis and update on future therapies, Luis Soro, Cynthia Bartus, and Stephen Purcell

Multidisciplinary ALS Clinics in the USA: a comparison of those who attend and those who do not, Helen E. Stephens, Stephanie Felgoise, Jared Young, and Zachary Simmons

A Qualitative Study of Multidisciplinary ALS Clinic Use in the United States., Helen E Stephens, Jared L. Young, Stephanie H. Felgoise, and Zachary Simmons

Mdivi-1, a Novel Mitochondrial Fission Inhibitor, Exerts Cardioprotective Effects in Myocardial Ischemia/Reperfusion (MI/R) Injury, Devon Stutzman, Carly Schmidgall, Israel Benjamin, Qian Chen, Cathy J. Hatcher, Robert Barsotti, and Lindon Young

Lung cancer overview: Focus on newer therapies, Sonia Amin Thomas

New and emerging therapies for Melanoma, Sonia Amin Thomas, A. G. Douglas, A. Rose, E. Dingsangha, and Valerie Tapia

Metformin represses androgen-dependent and androgen-independent prostate cancers by targeting androgen receptor, Yan Wang, Gaolei Lie, Dali Tong, Henna Parmar, Donald Hasenmayer, Wenqiang Yuan, Dianzheng Zhang, and Jun Jiang

The Risk of Risk Assessment: Pressure Ulcer Assessment and the Braden Sca;e, Ilene Warner-Maron

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A Novel Segmentation Approach For Brain Tumor in MRI, Yong Wei and Hugh Keith Brown

Forearm Fractures, Johnathan J. Whitaker, Brandon M. Tauberg, Michael S. Kwon, and Martin J. Herbert

Antibody Effector Functions Mediated by FcY-Receptors Are Compromised during Persistent Viral Infection, Andreas Wieland, Rangaiah Shashidharamurthy, Alice Kamphorst, Jinhwan Han, Rachael Aubert, Biswa Choudhury, Sean Stowell, Junghwa Lee, George Punkosdy, and et al.

The cost-effectivness of OM-86 in managing respiratory tract infections in China, Jianwei Xuan, Lijie Wang, Hongjun Yin, Dennis Xuan, Yan Zhou, and Shanlian Hu

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Effects of a particular heptapeptide on the IFN-α-sensitive CML cells, Fulan Yang, Fangzhi Chen, Xinxing Wan, Xi Zhou, Meijuan Zhou, Hanchun Chen, Junjiang Fu, and Dianzheng Zhang

Selective estrogen receptor alpha agonist GTx-758 decreases testosterone with reduced side effects of androgen deprivation therapy in men with advanced prostate cancer, Evan Y. Yu, Robert H. Getzenburg, Christopher C. Coss, Mark M. Gittelman, Thomas Keane, Ronald Tutrone, Laurence Belkoff, Robert Given, Joel Bass, and et al.

Submissions from 2014

Climatic Severity Victims of Upstream Water Piracy Strongly Evidencing Inland Water Depletion-Caused Global Warming vis-a-vis Cooling, M. M. Adel, Mahmood R. Hossain, and Saiyeeda F. Hossain

Pharmacist-Initiated Prior Authorization Process to Improve Patient Care in a Psychiatric Acute Care Hospital, Shari N. Allen and Mebanga Ojong-Salako

A Practical Guide to Concentrated Insulin for Pharmacists, Jennifer Andres and Jennifer N. Clements

A Possible Case of Gabapentin-Induced Mild Hyperglycemia, Jennifer Andres, Jennifer N. Clements, and Donna Salmiery

Postoperative cognitive dysfunction, Alzheimer's disease, and anesthesia, S. S. Arora, Jennifer L. Gooch, and P. S. Garcia

Transdermal Delivery of Proteins Using a Combination of Iontophoresis and Microporation, Yun Bai, Vishal Sachdeva, Hyun Kim, Phillip M. Friden, and Ajay K. Banga

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Genome-wide sequencing of small RNAs reveals a tissue-specific loss of conserved microRNA families in Echinococcus granulosus, Yun Bai, Zhuangzhi Zhang, Lei Jin, Hui Kang, Yongquiang Zhu, Lu Zhang, Xia Li, Fengshou Ma, Li Zhao, and et al.

Etiology and Pathogenesis of Late-Onset Alzheimer's Disease, Brian J. Balin PhD and Alan P. Hudson

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Rethinking the Core List of Journals for Libraries that Serve Schools and Colleges of Pharmacy., Robert D Beckett, Sabrina W. Cole, Hannah K Rogers, Skye Bickett, Christina Seeger, and Jennifer A McDaniel

Prize-based contingency management for the treatment of substance abusers: a meta-analysis, L. Benishek, K. Dugosh, K. Kirby, J. Matejkowski, N. Clements, B. Seymour, and David Festinger

Application of osteopathy in the cranial field to treat left superior homonymous hemianopsia, Murray R. Berkowitz

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BrowZine: A Review, Skye Bickett

Comparison of Indocyanine Green Fluorescent Angiography to Digital Subtraction Angiography in Brain Arteriovenous Malformation Surgery, Christopher J. Bilbao, Tarun Bhalla, Shamsher Dalal, Hiren Patel, and Amir R. Dehdashti

Respiratory syncytial virus: Diagnosis, prevention, and management of complications, Marie Katie Bozman, Carmen Echols, and Jennifer Andres

Evidence of Declining Empathy in Third Year Osteopathic Medical Students, Hilary M. Caruso and Bettina Bernstein

Marked improvement of vulvovaginitis of unknown origin in a pediatric patient - Case report, Jerome H. Check and Rachael A. Cohen

Severe Headaches from Intracranial Hypertension (Pseudotumor Cerebri) Abrogated by Treatment with Dextroamphetamine Sulfate, Jerome H. Check and Rachael A. Cohen

Sympathomimetic Amine Therapy Found Effective for Treatment of Refractory Chronic Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy), Jerome H. Check and Rachael A. Cohen

The Triad of Luteal Phase Ocular Migraines, Interstitial Cystitis, and Dyspareunia as a Result of Sympathetic Nervous System Hypofunction, Jerome H. Check and Rachael A. Cohen

Failure to Improve a Thin Endometrium in the Late Proliferative Phase with Uterine Infusion of Granulocyte-Colony Stimulating Factor, Jerome H. Check, Rachael A. Cohen, and J. K. Choe

Methamphetamine abuse usurps hippocampal neural network operations undergirding memory consolidation, Sanika Chirwa, Adwoa Aduonum, and Habibeh Khoshbouei

The Impacts of Comparative Anatomy of Electric Rays (Batoidea: Torpediniformes) on their Systematic Hypotheses, Kerin M. Claeson

A Revision of the Upper Cretaceous Lepidosirenid Lungfishes from the Quseir Formation, Western Desert, Central Egypt, Kerin M. Claeson, Hesham M. Sallam, Patrick M. O'Connor, and Joseph J. W. Sertich

Response to letter to the editor: A practical guide to concentrated insulin for pharmacists, Jennifer Clements and Jennifer Andres

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Predictors and moderators of treatment response in childhood anxiety disorders: Results from the CAMS trial, Scott N. Compton, Tara S. Peris, Daniel Almirall, Boris Birmaher, Joel Sherrill, Phillip C. Kendall, John S. March, Elizabeth A. Gosch, Golda S. Ginsburg, and et al.

Somatic Complaints in Anxious Youth, Sarah A. Crawley, Nicole E. Caporino, Boris Birmaher, Golda Ginsburg, John Piacentini, Anne Marie Albano, Joel Sherrill, Dara Sakolsky, Scott N. Compton, Moira Rynn, James McCracken, Elizabeth Gosch, Courtney Pierce Keeton, John March, John T. Walkup, and Philip C. Kendall

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Phenotype of Transgenic Mice Carrying a Very Low Copy Number of the Mutant Human G93A Superoxide Dismutase-1 Gene Associated with Amyotrophic Lateral Sclerosis, Jeffrey S. Deitch, Guillermo M. Alexander, Andrew Bensinger, Steven Yang, Juliann T. Jiang, and Terry D. Heiman-Patterson

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Tbx5 is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis., Nata Y Diman, Gabriel Brooks, Boudewijn P Kruithof, Olivier Elemento, Jonathan G Seidman, Christine Seidman, Craig T Basson, and Cathy J. Hatcher

Incorporation of pazopanib in maintenance therapy of ovarian cancer, A. DuBois, A. Floquet, J. Kim, J. Rau, J. Del Campo, M. Friedlander, S. Pignata, K. Fujiwara, Rocco J. Crescenzo, and et al.

The Survey of Treatment Entry Pressures (STEP): identifying client's reasons for entering substance abuse treatment, K. Dugosh, David Festinger, K. Lynch, and D. Marlowe

Developing an index to measure the voluntariness of consent to research, K. Dugosh, David Festinger, D. Marlowe, and N. Clements

Contingency management for cocaine treatment: Cash vs. vouchers, David Festinger, K. Dugosh, K. Kirby, and B. Seymour

Achieving new levels of recall in consent to research by combining remedial and motivational techniques, David Festinger, K. Dugosh, D. Marlowe, and N. Clements

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Malnutrition and Depression, Katherine E. Galluzzi, Barry Rovner, and Stephen Di Sabatino

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Myo/Nog Cells: Targets for Preventing the Accumulation of Skeletal Muscle-Like Cells in the Human Lens, Jacquelyn Gerhart, M. Greenbaum, V. Scheinfeld, P. Fitzgerald, M. Crawford, A. Bravo-Nuevo, M. Pitts, and Mindy George-Weinstein

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Immediate Return to Ambulation and Improved Functional Capacity for Rehabilition in Complex Regional Pain Syndrome following Early Implantation of a Spinal Cord Stimulation System, Brandon Jesse Goff, Jeremy Wingseng Naber, John Patrick McCallin, Edward Michael Lopez, Kevin Brant Guthmiller, Karl Alan Lautenschlager, Tristan Toll Lai, Dean Harry Hommer, and Gonzalez Raul Marin

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Targeting the immune system to treat hypertension: Where are we?, Jennifer L. Gooch and Avadhesh C. Sharma