Clinical management and multipotential treatment strategies for blast-induced traumatic brain injury (bTBI)
Objective of review: To gain an understanding of current clinical management, treatment strategies and sequelae of blast-induced traumatic brain injury (bTBI). Due to the nature of bTBI, the focus is placed on military populations. Recent findings: With the increased use of body armor in the military, injuries that were once considered to result from secondary and tertiary blast effects are increasingly being attributed to primary blast effects. The occurrence of vasospasm and post-traumatic stress disorder (PTSD) symptoms appear to be more frequent in bTBI than with other mechanisms of brain injury. Diketopiperazine therapy and hyperbaric oxygen therapy are multipotential treatment designs for bTBI. Conclusions: Due to the increased occurrence of bTBI as a result of modern warfare, a collaborative effort is required by all medical personnel involved in the clinical management, assessment and treatment processes in order to increase the probability of favorable outcomes.
Malie, Patrick M. and Berkowitz, Murray R., "Clinical management and multipotential treatment strategies for blast-induced traumatic brain injury (bTBI)" (2012). PCOM Scholarly Papers. 739.
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