Getting the T-box dose right
Holt-Oram syndrome has been associated with mutations in the T-box transcription factor TBX5, but little is known about the function of this protein or how mutations in it cause disease. A new mouse model of this syndrome will help to answer some of these questions.
Hatcher, Cathy J. and Basson, Craig T., "Getting the T-box dose right" (2001). PCOM Scholarly Papers. 510.
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