Effects of dexamethasone on phospholipase activities in palate mesenchyme cells in vitro.

Authors

K P Chepenik
Mindy George-Weinstein, Philadelphia College of Osteopathic MedicineFollow
R M Greene

Document Type

Article

Publication Date

8-1-1985

Abstract

Treatment of primary cultures of palate mesenchyme cells from AJAX strain embryos with dexamethasone inhibited only phospholipase activity expressed at pH 7.5. A similar treatment did not have such an effect on palate mesenchyme cells from C57BL/6J strain embryos. Since the AJAX strain embryo is sensitive to the induction of cleft palate by exogenous glucocorticoids and the C57BL/6J strain is less so, these data allow consideration of phospholipase activity as a site of regulation for development of the palate.

Publication Title

Teratology

Volume

32

Issue

1

First Page

119

Last Page

123

PubMed ID

4035584

Comments

This article was published in Teratology, Volume 32, Issue 1, Pages 119-123.

The published version is available at http://dx.doi.org/10.1002/tera.1420320116.

Copyright © 1985.

Recommended Citation

Chepenik, K P; George-Weinstein, Mindy; and Greene, R M, "Effects of dexamethasone on phospholipase activities in palate mesenchyme cells in vitro." (1985). PCOM Scholarly Papers. 1780.
https://digitalcommons.pcom.edu/scholarly_papers/1780