Event Title
Coherence between Vibrissal Sensory Areas of Cerebellum and Neocortex with or without Active Movements of the Whiskers
Location
Georgia Campus
Start Date
7-5-2014 1:00 PM
Description
Our previous studies have demonstrated that simultaneous recordings from vibrissal-responsive sensory regions of the cerebellum and neocortex illustrated a high degree of cross correlation. We also observed that the cross correlation changes after stimulating the facial motor nerve to induce “artificial whisking” in anesthetized rats. Thus a further study using a different analysis is necessary to better our understanding of how cerebellar cortical activity is regulated by neocortical input. This is essential to gaining insight into cerebellar function and involvement in neurological diseases. In this study, we used coherence analysis to investigate the relationship between the activities from these two regions in frequency domain. The results from 5 pairs of recordings showed an average 0.8 coherence magnitude at 100 Hz frequency. This relatively high level of coherence may suggest that significant signaling events are transmitted between the neocortex and the cerebellum. In order to further investigate the nature of this correlating signal between these two areas, we will analyze the stimulated signals induced by “artificial whisking” and see if those results show a similar coherence at 100 Hz.
Coherence between Vibrissal Sensory Areas of Cerebellum and Neocortex with or without Active Movements of the Whiskers
Georgia Campus
Our previous studies have demonstrated that simultaneous recordings from vibrissal-responsive sensory regions of the cerebellum and neocortex illustrated a high degree of cross correlation. We also observed that the cross correlation changes after stimulating the facial motor nerve to induce “artificial whisking” in anesthetized rats. Thus a further study using a different analysis is necessary to better our understanding of how cerebellar cortical activity is regulated by neocortical input. This is essential to gaining insight into cerebellar function and involvement in neurological diseases. In this study, we used coherence analysis to investigate the relationship between the activities from these two regions in frequency domain. The results from 5 pairs of recordings showed an average 0.8 coherence magnitude at 100 Hz frequency. This relatively high level of coherence may suggest that significant signaling events are transmitted between the neocortex and the cerebellum. In order to further investigate the nature of this correlating signal between these two areas, we will analyze the stimulated signals induced by “artificial whisking” and see if those results show a similar coherence at 100 Hz.