Date of Award

2023

Degree Type

Selective Evidence-Based Medicine Review

Degree Name

Master of Science in Health Sciences - Physician Assistant

Department

Physician Assistant Studies

Abstract

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “is mindfulness- based stress reduction (MBSR) more effective than standard care in reducing anxiety in breast cancer survivors with a diagnosis of Stage 0 – III breast cancer?”

STUDY DESIGN: Review of three randomized control trials (RCT).

DATA SOURCES: All three RCTs were published in English and taken from peer-reviewed journals using PubMed. The articles were published between 2012-2021.

OUTCOMES MEASURED: The outcome measured included reduction in anxiety using the State-Trait Anxiety Inventory and POMS total mood disturbance (and its subscale of anxiety).

RESULTS: In the 2014 RCT led by Lengacher et al, there was no significant difference between MBSR and usual care, indicated by a p-value of 0.17. The 2021 RCT study led by Lengacher et al. showed a reduction in anxiety in the MBSR group compared to the UC group, indicated by a p-value of 0.01 and a mean change from baseline of 3.8. The RCT led by Hoffman et al. showed a statistically significant difference between the MBSR and UC groups. There was a mean change adjusted at baseline of 2.93 and a 95% confidence interval of -4.67 to -1.20. CONCLUSION: This systemic review had inconclusive results and could not determine if MBSR is more effective than standard care in reducing anxiety in breast cancer survivors.

Share

COinS